Simon Jones

Obesity Reprogrammes Adipose Extracellular Vesicles to Induce Muscle Atrophy via miR‐150‐5p‐Mediated Transcriptional Silencing Journal of Cachexia, Sarcopenia and Muscle. #Sarcopenia #obesity #ageing @BirminghamBRC @UoBinfectionsch onlinelibrary.wiley.com/doi/10.1002/jc…

My review on the preclinical and clinical evidence for the efficacy of GLP-1 and GIP Receptor Agonists in Chronic Inflammatory Disorders: Mechanisms and Therapeutic Horizons sciepublish.com/article/pii/832

Josh Price presenting our work on obese adipose EVs inducing muscle atrophy at the Society on Sarcopenia, Cachexia & Wasting Disorders #scwdnews Rome 2025. #extracellularvesicles #ev #muscle @unibirmingham @BirminghamBRC

Obesity reprogramming of adipose extracellular vesicle cargo induces human muscle atrophy. Our latest research preprint now published. @BirminghamBRC @UoBinfectionsch biorxiv.org/content/10.648…

@owenjonesjourno @paulmasonnews Owen. You lost the plot attacking Paul Mason as being vile. You are becoming irrelevant with your irrational outbursts and blocking of anyone who disagrees with your tweets.

Here's an example of what a vile, dishonest hack @paulmasonnews is. In my video, I said Israel's genocide had opened people's eyes to the evil our rulers and media outlets are capable of. And this would encourage people to fight all injustice, not just in Palestine.

Our BRC funded PhD student Bradley Welsh presents his research into PRPS mediated nucleotide synthesis and its role in building muscle mass. Sarcopenia and MultimorbidityBRC @BirminghamBRC

Daisy Wilson provides and an update on clinical interventions to reduce signatures of biological ageing in older people. Sarcopenia and Multimorbidity BRC. @BirminghamBRC @InflamAge_UoB

Sally Fenton presents on behalf of our BRC funded PhD student Florentia Kitas on intervention strategies to reduce sedentary behaviour in RA patients. Sarcopenia and Multimorbidity BRC. @BirminghamBRC

Sofia Ahola presents her research on stress responses and metabolic changes upon mitochondrial dysfunction and its relevance to #sarcopenia and multimorbidity. #ferroptosis @BirminghamBRC

Amanda Sardeli shows how physical activity modulates immune function in older people. More impactful patient centric research at our Sarcopenia and Multimorbidity BRC away day. @BirminghamBRC @InflamAge_UoB @amandasardeli @Duggal_UoB

Dilan Dibare, consultant kidney transplant surgeon, investigating frailty and prehabilitation intervention strategies for CKD patients. Sarcopenia and Multimorbidity BRC @BirminghamBRC

Niharika Duggal shows how features of immune ageing are present at the earliest stages of RA. Sarcopenia and Multimorbidity BRC @BirminghamBRC @InflamAge_UoB

Paula Rudzinska, BRC funded student for Sarcopenia and Multimorbidity theme, explains how targeting mitochondrial dysfunction can rejuventate older stem cells. @BirminghamBRC @InflamAge_UoB

Ana Crastin, BRC funded PhD student with Rowan Hardy for Sarcopenia and Multimorbidity provides an update on her research into glucocorticoids, macrophage activity and sarcopenia @BirminghamBRC

Michael MacLeod kicking off the talks at our Sarcopenia and Multimorbidity BRC away day @BirminghamBRC @InflamAge_UoB

@SaulStaniforth @owenjonesjourno carry on criticising starmer and labour at every opportunity and you are opening the door to a facist reform government. Try and be more constructive otherwise you are enabling facists

Keir Starmer is asked how digitial IDs will cut down on people working illegally. He can't say.

From fat to flame: How adipose tissue stokes the fires of osteoarthritis - Osteoarthritis and Cartilage @BirminghamBRC @InflamAge_UoB oarsijournal.com/article/S1063-…

onlinelibrary.wiley.com/doi/10.1111/ob… Delighted that @MRC_AIM_DTP student Michael MacLeod's review on #adipose #ExtracellularVesicles in skeletal #muscle is now published in Obesity Reviews. @BirminghamBRC @InflamAge_UoB

Dr Michael Sagmeister has been nominated Deputy Theme Lead for our #Sarcopenia & #Multimorbidity research theme. Michael specialises in renal medicine at @unibirmingham & @uhbtrust and will work alongside Prof @UoB_JonesLab - congratulations! 👏

@psalmotoxin @OACJournal Great work

Our paper showing that sphingomyelin 34:1 (⬆️ in🧍osteoarthritis synovial fluid) sensitises🐁sensory neurons in vitro & causes pain behaviours + knee-innervating neuronal hyperexcitability in 🐁 in vivo is now out in @OACJournal sciencedirect.com/science/articl… Tweetorial 👇 #neuroscience