Christiane Wrann, PhD, DVM

In mice, regular workouts spur neurogenesis, as well as transcriptomic changes across cell types. Exercise also corrected some signatures of AD. @MassGeneralNews ow.ly/kBcQ50WfP0K

Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing @WrannLab, @MGBResearchNews, @NR_Tucker, @UpstateResearch nature.com/articles/s4159…

RESEARCH UPDATE 🔬: Exciting new research findings reveal that exercise induces beneficial changes in various brain cell types and may result in a reversal of some Alzheimer's-related brain changes. The study, driven by #ALZFunded researcher Christiane D. Wrann, DVM, Ph.D. (@WrannLab), enhances our understanding of disease-related brain changes and underscores the potential of lifestyle interventions to mitigate disease progression. We look forward to hearing more about the impact of lifestyle interventions on brain health through the results of our U.S. POINTER study, which will report findings at #AAIC25 this summer. #AlzResearch

In a new study, researchers from @WrannLab at @MassGeneralNews and colleagues discovered how exercise can protect the brain at the cellular level from #Alzheimers disease. The study was published in @NatureNeuro. Read more: massgeneralbrigham.org/en/about/newsr… nature.com/articles/s4159…

Our latest study is out in Nature Neuroscience! 🧠💪We dissected protective exercise responses in the dentate gyrus in Alzheimer's disease at single-cell resolution. Proud of the team's hard work and collaboration! 🔗 doi.org/10.1038/s41593… @mghcvrc @NR_Tucker @MGBResearchNews @mghNeuroSci @UpstateResearch @NatureNeuro #Neuroscience #BrainHealth #ExerciseScience #Alzheimers #AcademicTwitter