
Anoop Mehendale
1K posts

Anoop Mehendale
@aprateem
health tech, data and enterprise AI entrepreneur with exits; healthcare exec experience across payer, provider, pharma



the next massive consumer ai opportunity is making personal agents feel as intuitive as an iphone. this is deeply important because this is the new software layer for everyday life. most ppl do not want to configure workflows, manage prompts, route models, or think about agents at all. they want software that just works & the winning products will hide almost all of the complexity with taste incl. context, memory, & orchestration. e.g. there’ll be baseline personal agents that come alive out of the box which are already understanding your context, patterns, relationships, preferences, apps, devices, routines, etc. then there’ll be ephemeral agents that spawn dynamically from intent, ambient capture, conversation, location, screenshots, email, calendar, camera roll, whatever. this is the software that assembles itself around the moment just like weather updates based on your location but way more in depth. today even the most state of the art agent products feel like giving normal people shell access to a distributed system. apple won by turning computers from something you operated into something you experienced. personal agents require the same transition. whoever solves this becomes the ambient operating system for human life. small category btw.






Building apps has never been easier. With Sites, Codex can turn your work, ideas, and plans into an interactive website or app your team can explore, use, and share with a URL. Rolling out to Business and Enterprise plans, before expanding more broadly.



15/ 6. When possible, meet your prospective customers in person. Even if it’s not scalable. You’ll greatly increase the likelihood the deal closes by building a relationship with the buyer.


1/ How to succeed with founder led sales: Last week, @garrytan was nice enough to invite me to his home to speak with the current YC batch. The most common topic was founders figuring out how to close the first set of customers in time for demo day.


The next evolution of Hermes Agent is here! Introducing Hermes Desktop: everything you love about Hermes, now native on your machine. First demoed in Jensen's GTC keynote, it's now in public preview.



"We have everyone do work trials so people know what they’re getting into on both sides. We like candidates to do real work for 1 or several days, often over a weekend. When they see the office full on a weekend, they quickly learn that we’re not joking around." @nico_laqua What are your single biggest lessons on how to test the quality of candidates pre-hiring @awxjack @ryanjdaniels @ivanburazin @rronak_


Imagine replacing 90% of your employees with a team of geniuses who have no idea how your company operates. Total chaos. Nothing works. That’s what AI feels like today. The missing piece is extracting all the domain knowledge from people’s heads and providing that as structured context to the models.


@ryancarson You can define a multi-factor scoring system across various “soft” dimensions (e.g., an “elegance” score between 0 and 1,000) that gets rolled into a single weighted overall score and suddenly make just about any problem have a numerical loss factor that you can optimize over.



