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Hon

@dr1337

Ex-medical doctor working on Synthetic Biology and Intelligence. CEO & Founder @corticallabs | Forbes 30 | software dev | Tweets represent my personal views.

Melbourne, Victoria เข้าร่วม Kasım 2008
507 กำลังติดตาม4.5K ผู้ติดตาม
Hon
Hon@dr1337·
@michaelfrazis Too bad Microsoft got blinded by the AI gold rush that they turned a diversified conglomerate into a single product company focused entirely on a sub-par offering
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Michael Frazis
Michael Frazis@michaelfrazis·
Correct take. Add in the enshittification of core Microsoft products like Outlook... which are now barely usable vs competitors, and it's exposed They still have many more chances to course correct, but investors were right to mark this down. Microsoft is also right to allow Anthropic and OpenAI inside the gates, as their greatest asset is inertia $MSFT
Evergreen Capital@evergreencap3

$MSFT faces a mounting strategic dilemma: They have no choice but to allow @AnthropicAI and @OpenAI to continue shipping agents inside Microsoft products, because 1) it allows users to derive more value from M365, likely boosting retention, and 2) blocking those companies from M365 would further incentivize them to launch their own full productivity suites (which may happen eventually anyway), creating risk of a major churn event (i.e., the worst-case scenario). But at the same time, the agents from those companies are so far superior to Microsoft’s @Copilot that more of the incremental AI revenue and value is being captured outside the M365 ecosystem. Moreover, users are increasingly using Claude/ChatGPT as the direct interface through which they accomplish AI work, building deeper relationships and stickiness with those tools, and less with M365. Something has to give. The longer this goes on, the weaker Microsoft's position gets. Microsoft must self-disrupt and completely reinvest itself for the new era. Otherwise, its dominance may slowly slip away.

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Hon@dr1337·
If this isn’t an indication that we’re in a bubble then I’m not sure what else will. Remember Long Island Ice Tea Blockchain? reuters.com/business/allbi…
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Alon
Alon@alonloeffler·
CORTICAL LABS PRESENTS: 🧠💾 CORTICAL DOS! 💾🧠 youtube.com/shorts/S-AqWTB… 1993's most revolutionary program to help you understand your synthetic biological intelligence experiments, built here in Melbourne (in 2026)!
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Sean Cole
Sean Cole@vytalow·
Hey everyone, I'll be giving a talk about the ethics and technical details of brain cells playing Doom this Wednesday at @Lorong_AI (SG government), if you want to attend you can sign up here! luma.com/qiyy2qa2
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Hon@dr1337·
@fkasummer Yeah but it’s lucrative.
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akhil
akhil@fkasummer·
Most AI researchers are not doing anything resembling research. Tuning parameters is not research.
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Hon@dr1337·
@4R7I5T @bambini_web3 @BioLLMbot You might want to check out the AI Max 395+ platform and just run an OSSModel on 128GB. You can cluster them together with USB 4 at 40 gbps
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4R7I5T@4R7I5T·
@bambini_web3 @BioLLMbot We just feel that the best possible product that’s most genuine is an in house trained LLM where we can control the inference & the way the model trains. The reality is most AI products are built completely different from what we need and at minimum we need to perform a fine tune
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4R7I5T
4R7I5T@4R7I5T·
Looking at moving @BioLLMbot & BioLLM.com away from API style service to a dedicated 30-70b param model
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Sophia
Sophia@sopharicks·
Godfather of neuroscience and author of The free energy principle (active inference), Karl Friston @KarlFristonNews , discussed with me his take on AGI, consciousness, why we will never fully understand the brain, and why humans tend to repeat their mistakes. Key moments: - You'll know AGI has arrived when the system starts asking you questions out of genuine curiosity, not because it was prompted to - You cannot hand an intelligent system a value function from the outside, it must learn its own, just as children do (in that sense, RL with assigned reward is the wrong direction) - The only sustainable universal objective function is adaptive fitness: how well the agent fits and survives within its ecosystem - Consciousness requires multiple layers: genuine agency, a self-reflective loop, and the ability to recognize your own states of mind - True sentience may be impossible on standard computer architecture, because memory and processing are separate and cannot self-organize - Understanding your own brain is philosophically impossible in the same way a ruler cannot measure itself - Neuroscience is always "peeking behind" the Markov blanket indirectly: through imaging, electrophysiology, psychology — never seeing inside directly - The only way to truly access the brain is to breach that boundary (e.g. neurosurgery), but a breached brain is no longer a normally functioning one Watch the full interview and let me know what you think. Link below👇
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CCP Hellmar
CCP Hellmar@HilmarVeigar·
CCP London got a 🤯 visit as @dr1337 of @CorticalLabs stopped by with his DishBrain computer. This thing seriously pushes the boundaries of the imagination - we need to up our game when comes to science fiction as science fact is catching up rapidly! Check out their educational video series From Cells to Code for more details: youtube.com/watch?v=Uk6YMY… and various other publications: corticallabs.com/mars/
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Hon@dr1337·
Was the highlight of my day! 🤓
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Hon@dr1337·
@pisi_pisi34 Good question - all possible however we haven’t looked into that as our sample size is small. What my observation is that environment is more important
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Pis pisi pisi@pisi_pisi34·
@dr1337 When sourcing human cells for neuron cultures, is donor selection random or based on factors like age, sex, or genetics? Could cells from individuals with higher cognitive ability lead to faster or more efficient learning?
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Hon@dr1337·
To clarify, Cortical Labs is a 7 year old company and the CL1 is a 3 year old project. Everything referencing this is retrospective. Prospective is figuring out the best applications and use cases are for biological compute with the CL1.
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François Chollet
François Chollet@fchollet·
This is more evidence that current frontier models remain completely reliant on content-level memorization, as opposed to higher-level generalizable knowledge (such as metalearning knowledge, problem-solving strategies...)
Lossfunk@lossfunk

🚨 Shocking: Frontier LLMs score 85-95% on standard coding benchmarks. We gave them equivalent problems in languages they couldn't have memorized. They collapsed to 0-11%. Presenting EsoLang-Bench. Accepted to the Logical Reasoning and ICBINB workshops at ICLR 2026 🧵

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Robert Scoble
Robert Scoble@Scobleizer·
Human neurons running in the cloud. The matrix is here. (I was the first to reveal this company back in 2023, still one of the most exciting, scary, and wild things I've ever seen).
Cortical Labs@CorticalLabs

This is Cortical Cloud. Live neural networks that you can interact with and train! Now open to the public. What will you discover? Credits: Frank Yang and a big thank you and acknowledgement to the rest of the Cortical Labs team. Sign up for Cortical Cloud: cloud.corticallabs.com Learn more about us: corticallabs.com Check out our API: github.com/Cortical-Labs/… Check out our API Docs: docs.corticallabs.com Check out our Developer Guide: github.com/Cortical-Labs/… Join our Discord: discord.gg/rtyphEqHzq

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Sean Cole
Sean Cole@vytalow·
Video generation code running on human brain cells is now open sourced here! github.com/SeanCole02/dif…
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Hon@dr1337·
@EchelonMirror Free markets for thee but not for me!
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Hon@dr1337·
With the rising cost of petrol and diesel affecting millions of Australians, I think it’s time to revisit the failures of our policymakers who have either failed to support or have only tepidly supported the electrification of our mobility infrastructure. Enough of blame-shifting between ALP and LNP governments. I had hoped that it didn’t take a conflict that closed the Straits of Hormuz to awaken how vulnerable a position we are when it comes to energy security. Our lack of indigenous oil supply and refinery capabilities puts us at the mercy of any any regional insecurity. We need to wake up to the fact that Australia is an energy superpower and can very easily be completely independent and sovereign if only we didn’t rely on imported fossil fuels. Say what you will about China but at least they saw this coming and have frenaticaly made the attempt to electrify their system and assert energy sovereignty.
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Hon@dr1337·
@PetrTyurin Not flying with organic materials but you can check out a CL1 that I brought with me
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petr tyurin
petr tyurin@PetrTyurin·
@dr1337 How can you fly with them? Like Organs?
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Hon@dr1337·
If anyone is in SF for GTC March 14 - 22 and in LA March 25 let me know as I'll be bringing along a CL1 with me to demo.
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Sean Cole
Sean Cole@vytalow·
last day in melb!
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