Tim van de Hoef

This study shows that coronary microvascular dysfunction, identified only by an impaired coronary flow reserve, was associated with increased rates of MACE and target vessel failure over a 5-year follow-up. #EAPCI ow.ly/L5mm50JwNe0

@DrOzanDemir @JACCJournals @PCRonline @mmamas1973 @ColletCarlos @JGrapsa @JEscaned @habib_samady @MauroEchavPinto @WijnsWilliam @SVRaoMD @ncurzen Great effort Ozan, and congratulations on the publication! Still looking for robust data on diagnostic or prognostic value of sole microvascular resistance measurements in chronic coronary syndromes and ANOCA, and this may be part of the reason why….

Comparison of Flow Study (Doppler vs Thermo) ➡️CFR-thermo overestimates CFR-Doppler (modest correlation) ➡️Commonly used CFR-thermo threshold 2.0 has poor diagnostic accuracy ➡️Optimal CFR threshold 2.5 (thermo OR Doppler) 🔗jacc.org/doi/10.1016/j.… @JACCJournals #EuroPCR2022

Summary of late-breaking clinical trials and science at #TCT2021. @crfheart @TCTMD #ACCFIT #AHAFIT #ACCIC #ACCEarlyCareer

An analysis of the TWILIGHT-HBR substudy by @ANazmiCalik @elif_ilkay9 published at @PCRonline bit.ly/3GYita0 @shci_sec @CardioRed1 @IIS_IdISSC @CaoDavide @Drroxmehran

@venkmurthy @drandrewsharp Under review for some time already, we hope to get this published soon. Much more come from this great collaboration.

@drandrewsharp Fascinating. Is a paper available?

Coronary Physiology Strikes Back?! ILIAS Registry shows that FFR guidance may be strengthened by the addition of coronary flow measurements in stable IHD. RCT needed here to change practice. #TCT2021

iFR and FFR with similar outcome at 5-years! No difference in any subgroup or components of the composite outcome. “iFR is quicker, easier, cheaper and with no discomfort for the patient. iFR lowers the threshold for performing physiology!” @DLBHATTMD @TCTConference

@DrOzanDemir @venkmurthy @UKheartresearch @JEscaned @hect2701 @TCTConference @PCRonline @TCTMD @Guusdewaard @ncurzen @mmamas1973 @RicardoPetraco @MauroEchavPinto @h_evald Thanks for the support @DrOzanDemir! We hope to get this published soon.

@venkmurthy @UKheartresearch @JEscaned @hect2701 @TCTConference @PCRonline @TCTMD @drTPH @Guusdewaard @ncurzen @mmamas1973 @RicardoPetraco This is #TCT2021 abstract by @MauroEchavPinto @JEscaned @h_evald @drTPH et al Abstract PDF attached

Important messages - 1. Functional CMD has same poor prognosis as structural CMD. 2. High MR alone does not carry poor prognosis - it should not be used to diagnose CMD in isolation. For diagnosis - 1. Measure CFR 2. Then endotype by MR as may have therapeutic implications.

Event rates 1/2 w/ #iFR deferral vs #FFR per @jerd10 in LAD & #ACS

Wow, this chap appears to have read the #ORBITA paper, the appendix and the refs, as well as the abstract, other tweets and TCTMD! Kudos. twitter.com/anilmakam/stat…

ORBITA trial: PCI significantly reduced ischemia but no improvement in exercise time compared to placebo procedure #TCTDenver

Dr. Al-Lamee explains ORBITA: rand, sham-cntrl trial of PCI in pts w/CAD watch full interview here tv.clinicaltrialresults.org/play.php?submi… #TCTDenver

Dr. Al - Lamee discusses results of ORBITA Trial in this mornings press conference #TCTCDenver

#ORBITA #tctdenver

A substantial percentage of US journal editors received personal payments from industry and these payments were often large, finds #BMJResearch bmj.com/content/359/bm…

#orbita giant Rasha...

@ZaherFanari @ajaykirtane @crfheart @GreggWStone @MartyMleon @Drroxmehran @CMichaelGibson @ZaherFanari @ajaykirtane First things first, ORBITA to be presented tomorrow! #TCT2017

Can't be right that 8 fold difference between operators for #radialfirst approach in STEMI. Not right for patients interventions.onlinejacc.org/content/early/…

The call for the 2018 Einthoven dissertation prizes is open. Deadline 5-1-2018. Check our website heart-institute.nl for details.

Here’s a clearer picture. Deferring lesions in the LAD using FFR is associated with a doubling in clinical events compared to iFR #TCTDenver