TransQST project

After ~6 years of fruitful partnership, we are proud to announce the launch of a booklet with TransQST results: “Advances in Quantitative Systems Toxicology – The premise of TransQST”. Check it out on our website👇 transqst.org/results/ @IHIEurope #drugsafety #drugdiscovery

Our latest paper describing species differences in hepatic stress response pathway capacities is now out @ToxSci. Funded by @transqst @The_MRC. We're now exploring the broader scope, mechanistic basis and implications of these differences - more to come! doi.org/10.1093/toxsci…

Seasons greetings from TransQST and happy holidays to all!

The BioModels - Model of the Year Competition 2023 is now open! We encourage all modellers to submit their models and enter the competition. Check it out here: ebi.ac.uk/about/news/upd…

We are happy to announce that a new TransQST article has been published in Archives of Toxicology: pubmed.ncbi.nlm.nih.gov/36203040/

TransQST symposium was hold today as part of the #ICT2022 congress. Congratulations to all the team for their excellent presentations! #Toxicology #drugdevelopment

In the new edition of our 'Meet the team' section, we interview our colleagues from UNIVIE. They share with us their vision of the project and of the main challenges and achievements during these past five years: transqst.org/news/interview…

Our colleagues from University of Leiden has published a new article in the Plos Computational Biology journal. You can now check this paper here: journals.plos.org/ploscompbiol/a…

You can now read the interview to our colleagues from SYNAPSE taking care of project management and dissemination activities in TransQST. Find the interview here: transqst.org/news/interview…

We are happy to share a recent paper from our UKHD colleagues published at the journal Expert Systems with Applications. You may find it here: doi.org/10.1016/j.eswa… @saezlab @attila_gbr

"At Eli-Lilly, our main focus in TransQST has been on the development of haemodynamic and cardiac models, and we have also been involved in developing new models for liver injury processes", explains Derek Leishman. You can read the entire interview here: transqst.org/news/interview…

Our colleagues from UM work to establish the biological impact of exposures to potentially toxic compounds and to develop safe therapeutic strategies for genetic and non-genetic diseases. We had the opportunity to interview them, find it published here: transqst.org/?p=1671&previe…

A new interview just came out from the oven! This time Sylvain Fouliard, Stéphanie Billiald and Nicolas Sajot from IRIS share with us their experience of working in the TransQST project. You can read it here: transqst.org/news/interview…

Another project milestone accomplished! Article showcasing work from the TransQST Heart workpackage has been published in Frontiers in Pharmacology. You can read it here: frontiersin.org/articles/10.33… #drugsafety #drugdiscovery

"TransQST has a realistic and undogmatic approach which allowed researchers to adapt to surprising realities revealed by unexpected experimental data" explain IFADO, our colleagues especialised in liver physiology. You can read their entire interview here: transqst.org/news/interview…

TransQST partner UOXF: "TransQST has allowed us to understand the challenges in safety pharmacology and toxicology, and how modelling and simulation methods can contribute to the field". Check out the whole interview here: transqst.org/news/interview…

Thank you for attending the #9thTransQSTGAM! A special thanks to all the consortium and SAB members and our regulatory colleagues for their excellent presentations! @IHIEurope #insilico #drugsafety #drugdiscovery

All set to continue with the #9thTransQSTGAM The session of this afternoon will shed light on upcoming IHI calls and future projects to continue with the legacy of TransQST. @IHIEurope #insilico #drugsafety #drugdiscovery

The Day 2 of the #9thTransQSTGAM has just started! The first sessions will be focused on regulatory credibility for models and sustainability of project tools. @IHIEurope #insilico #drugsafety #drugdiscovery

We will soon close Day 1 of #9thTransQSTGAM. Thank you all the consortium members for your excellent presentations and joining the fruitful discussions! @IHIEurope #insilico #drugsafety #drugdiscovery