Nicole Pek (she/her) รีทวีตแล้ว
Online Now! Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia dlvr.it/TQ0H2z #stemcells
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Nicole Pek (she/her)
692 posts
Nicole Pek (she/her)
@two_cells
PhD Candidate @cincychildrens @UcincyMedicine •@AHAScience Fellow •Albert J. Ryan Fellow •@NUSingapore Young Fellow •Founder @npbiomeds (Views = my own)
Cincinnati, OH เข้าร่วม Ağustos 2020
705 กำลังติดตาม338 ผู้ติดตาม
Join me next week in @vascularbiology's InFocus Session, where I'll be giving a short presentation on my thesis project 'Distinct Functional Consequences of FOXF1 Mutations in Capillary Development'. Registration is free: shorturl.at/T12dx
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Nicole Pek (she/her) รีทวีตแล้ว
Drs. @SimonMiao6, Nicole Pek (@two_cells), and Drs. Minzhe Guo and @MingxiaGu's labs co-differentiated mesoderm and endoderm in the same spheroid to vascularize lung and intestinal #organoids!
@CellCellPress article: bit.ly/3H1ar4V
Discussion: bit.ly/44YrzjU
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Thrilled to share that I’ve been selected as one of 19 recipients for the 2025 @GenScript Life Science Research Grant (First Award Cycle). This grant will support our efforts to validate the utility of LNP-mRNA in treating vascular diseases.
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Nicole Pek (she/her) รีทวีตแล้ว
@MingxiaGu @CellCellPress @CuSTOM_CCHMC @UCLAstemcell Read more at our Research Horizons science blog: scienceblog.cincinnatichildrens.org/first-lung-org…
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Nicole Pek (she/her) รีทวีตแล้ว
Excited to share our recent work on organoid vascularization, now out in @CellCellPress! Grateful to all our amazing collaborators who made this possible! @CuSTOM_CCHMC @UCLAstemcell
Darrell Kotton@Kottond
Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! "Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids" cell.com/cell/fulltext/…
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By employing developmental principles, we were able to overcome long-standing challenges in the field - 1) inadequate vascularization of gut organoids, 2) ECs and mesenchyme void of organ-features. A major milestone in vascular biology organoid research!
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Our Cell paper is now online!! 💡We share a mesoderm-endoderm co-differentiation strategy to achieve organ-specific #endothelial & #mesenchymal cells in vascularized #lung and intestinal #organoids. 🔗sciencedirect.com/science/articl…
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Nicole Pek (she/her) รีทวีตแล้ว
Excited to share our latest study showing that restoring the balance between NTRK2 isoforms offers a promising therapeutic approach to promote pulmonary vascular regeneration! biorxiv.org/content/10.110…
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Nicole Pek (she/her) รีทวีตแล้ว
Your lungs make blood too. UCSF scientists just discovered lung stem cells that produce blood, just like bone marrow. This could change how we treat blood and immune disorders. tiny.ucsf.edu/Pwa7qn
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Nicole Pek (she/her) รีทวีตแล้ว
Our new metabolic method to generate highly-pure hepatocyte-like cells is out in @biorxivpreprint where we study the effect of biosafety-level-4 viruses using these purified hepatocyte-like cells.
biorxiv.org/content/10.110….
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Thankful for the partnership with @miltenyibiotec , whose cutting-edge products are vital to my research. Their solutions are key to my work on stem cell-derived vessel organoids for modeling disease and development, making a huge impact on my progress. shorturl.at/0zs2v
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Nicole Pek (she/her) รีทวีตแล้ว
@WindDustStars Women are naturally less interested in these fields and that’s why they are less active in STEM? That’s total bs. For one, maybe look up the misogyny women in STEM experience - from daily interactions all the way up to the Nobel! education.nationalgeographic.org/resource/women…
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Curious about how our brain distinguishes 'doorbells' from 'eggs' or know when words are gibberish? Don't miss my latest blog article where I dissect a recent study that uncovered how our brain processes semantic information at a single-cell level - shorturl.at/Re6rh
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Nicole Pek (she/her) รีทวีตแล้ว
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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Amazing to see Dr. @TakebeLab and team's study on 'butt-breating' receive such an incredible accolade and recognition. If you'll like to learn more about anal breathing, I wrote a an article on my blog a couple months back on this - shorturl.at/LS0h9 Please check it out!
Cincinnati Children’s Research@CincyResearch
Can people really breathe through their butts? Mammals can. So people probably can, too. Congrats to @TakebeLab @CuSTOMOrganoids @CincyChildrens One of 10 winners of a 2024 #IgNobel Prize! Read more: scienceblog.cincinnatichildrens.org/ig-nobel-prize… Watch the ceremony: improbable.com/ig/archive/202…
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A massive milestone for @npbiomeds!! We are constantly looking for new projects - if you are looking for biomedical experts for your writing/ editing/ research needs, please reach out! If you know anyone who might benefit from such services, point them in my direction! 🙏🏻
npbiomeds@npbiomeds
As summer winds down, we're thrilled to announce that we’ve secured four major contracts in the past few months—two in biopharma and two in education. We’re still open to new opportunities, so don’t hesitate to reach out!
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Nicole Pek (she/her) รีทวีตแล้ว
Now published in the Sept. 5 issue of @CellCellPress: A holistic view of the vascular endothelium as a systemically disseminated organ. Go to cell.com/cell/fulltext/… if you want to learn more about the beauty and importance of endothelial cells in health and disease.
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Nicole Pek (she/her) รีทวีตแล้ว
Astonishing breakthrough in #organoid engineering, as reported in @Nature by T Recaldin,M Harter,L Steinacher,B Gjeta, and colleagues: intestinal epithelial organoids incorporating tissue-resident immune cells. @IHB_Research @Roche go.roche.com/4a5t1
Gray Camp@GrayCampLab
Exciting new inroads into human biology and therapy development: Human intestinal organoids with an autologous tissue-resident immune compartment! #Gjorevski #Cabon #IHB @Nature @IHB_Research #MOESM4" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…
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