Biocatalysis Lab

Happy to announce that our 2nd publication in @ACSCatalysis on "Biocatalytic Access to Chiral Benzazepines" is online now. Grateful to @serbonline & @cbmrofficial for funding. Credit goes to @AnshulR39996389 @TanayaManna and others for this great work. pubs.acs.org/doi/10.1021/ac…

Happy Women’s Day to all the hardworking and passionate women who have been part of the #BiocatalysisLab @HusainLab over the past decade. 🌸🔬 Your dedication, talent, and contributions have been invaluable to our journey and success.

Glycogen synthesis is crucial for energy utilisation in humans, as glycogen is the excess glucose stored in the liver and muscles for future use. Glycogen levels can vary significantly from person to person, influenced by metabolic rates, physical activity and dietary habits. People diagnosed with Glycogen Storage Disorders have 100-200 times higher glycogen reserves. Excess glycogen triggers multiple adverse and toxic reactions, leading to myopathy, muscle wastage, liver and heart failure, serious cognitive impairment and neurodegenerative risks. We report patented purine molecule scaffold as an orally active alternative to enzyme injections, potentially transforming treatment for Pompe disease and other GSD variants. Stay tuned.. @IITKanpur happiesthealth.com/articles/muscl…

Delighted to share that our work on "Biocatalytic Asymmetric Synthesis of Diversely Substituted Dihydro‐1,4‐2H‐Benzoxazines and Benzothiazines" got published in Chemistry – An Asian Journal aces.onlinelibrary.wiley.com/doi/10.1002/as… congratulations to all the authors @HusainLab

The 13th Scientific Advisory Committee Meeting of CBMR was held on 9 February. Faculties presented their research progress in biomedical research and received comments and suggestions from the members, with a focus on patient care. @myogiadityanath @BrijeshpathakUp @ChiefSecyUP

𝗔𝗡𝗥𝗙 | 𝗨𝗽𝗰𝗼𝗺𝗶𝗻𝗴 𝗖𝗮𝗹𝗹𝘀 𝗮𝗻𝗱 𝗞𝗲𝘆 𝗧𝗶𝗺𝗲𝗹𝗶𝗻𝗲𝘀 #ANRFIndia invites the research community to take note of the upcoming calls and key timelines & begin preparing accordingly.

.@IITKMedSchool is back with instructional R&D videos on Maternal Health &Innovation: Advances in Research and Technology. This curated series of expert video lectures explores digital screening tools and bioengineered platforms to translational research bridges that connect laboratory insights with clinical care. This is result of a collaborative efforts with Women’s Collective Forum, a non-government organization committed to advancing gender equality, equity, and addressing critical challenges in public health, education, and economic empowerment. Lecture 1 in the new series: Placenta-on-chip: A step towards better maternal health by Prof Abhijit Majumder @abhijit_MLab from @iitbombay. youtu.be/1llwq99XJYE?si… via @YouTube @IITKanpur @Director_IITK @AwasthiAwanishK

Prof Alasdair McDowall AM – the recipient of Dubochet Nobel Medal 2017 – delivered a brilliant special evening lecture in FORCE-IICS 2025 on his journey toward discovery of rapid cooling of water to create vitrified glass-like state, while working with Prof Jacques Dubochet (Nobel Prize in Chemistry 2017) at the European Molecular Biology Laboratory. His pioneering efforts afforded an invaluable tool to preserve biological samples in a hydrated state for high-resolution cryo-electron microscopy. An inspiring lecture touching on interdisciplinary science and service to the society.

Vibrant participation in Indo-German Workshop 2025 at Goethe University Frankfurt. Amazing lectures in chemical biology, light mediated systems, advanced materials, organic synthesis, and computational approaches. Exciting meeting with excellent ideas germinating for collaborative bilateral projects. @softpolaron @TaniyaChkrabort @DivyaKumar182

Tradition of fun continues - Indo-German Workshop 2025 participants took a leisure trip to the Taunus, with drizzle and fog adding to the adventure and picturesque scenery. The Taunus Hills Nature Park is just outside Frankfurt and the second largest nature park in the Hessian region. It covers ~1,350 sq km area and provides perfect conditions for native flora and fauna, exciting hiking, climbing, cycling trails and canoe adventures. en.m.wikipedia.org/wiki/Taunus

We have a project JRF position in our lab sponsored by ANRF. Interested candidates with background in chemical sciences are encouraged to apply. For more on the work visit husainlab.net @HusainLab last date is September 15, 2025.

@LabMukherjee @J_A_C_S @iiscbangalore @RaySayanray @SyngeneIntl @serbonline Congratulations to the team!

Just out in @J_A_C_S now from @iiscbangalore: Enantioselective Total Synthesis of [5]-Ladderanoic Acid pubs.acs.org/doi/10.1021/ja… Congratulations @RaySayanray, Deepak, and Prava. Thank you, Pradip and Subrata, for a fruitful collaboration. Thank you @SyngeneIntl & @serbonline

Delighted to share our recent work on "Stereodivergent Synthesis of Diversely Substituted Dibenzoxazepines Using Imine Reductases" just got published in Organic Letters. Congratulations to Piyal, Sandipan, @manishaBairwa68 & @jhilikm64761696 @HusainLab pubs.acs.org/doi/10.1021/ac…

Go beyond the lab with Prof. Sandeep Verma - acclaimed scientist, academic leader, and educator at IIT Kanpur. In this candid interview, he talks about his journey in science, the joy of teaching, and what inspires him beyond research. A closer look at the person behind the accolades. youtu.be/aH0SC5Ua6lg #IITKFaculty #BeingCandid #Science #AcademicLife #leadership #teteatete #IITKanpur #iitk

Some thoughts on how to deepen German ties with smart Indians. Do take a look at what Germany has to offer in education, science, research, and engineering jobs!

#Biosynthesis of the Central Tricyclic Skeleton of Trichothecene Mycotoxins by Jinmin Gao, Dong Liu, Carolyn Nguyen, Susan P. McCormick, Robert H. Proctor, Shenggan Luo, Yike Zou (@yike_zou), and Yang Hai @yanghaiBioChem in @J_A_C_S pubs.acs.org/doi/10.1021/ja…

Delighted that it is accepted now. Congratulations to @TanayaManna, Piyal & @aniqah7866 of @HusainLab Biocatalytic Stereodivergent Synthesis of Substituted Tetrahydro‐Benzo‐(Oxa, Thia, & Di)‐azepines - Chemistry – A European Journal - Wiley Online Library …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…

I am so glad to share that Manisha Bairwa @manishaBairwa68 and Ajeet Shukla @ajeet_shukla75 from @HusainLab got the best posters prize at 34th CRSI Symposium @ChemResSocIndia held at @iiserbhopal. Thankful to @serbonline and @cbmrofficial for financial support to #biocatalysis

@Hari_Chakrapani @ChemicalScience @SimranGupta2312 @IISERPune @IndiaDST @ANRFIndia Congratulations to the team for the wonderful work!

Pleased to share our first manuscript in 2025 published in @ChemicalScience pubs.rsc.org/en/content/art…. Congratulations @SimranGupta2312 and Pratiksha! @IISERPune @IndiaDST @ANRFIndia for funding.

@pincersabuj @ACSCatalysis @madarsha098 @ChirantanMitra4 @n1Srabani @IITKanpur @serbonline @ANRFIndia @IndiaDST Congratulations to the team

Please have a look at our recently developed strategy in @ACSCatalysis to synthesize vastly useful alkenyl ketones and nitriles. Congratulations @madarsha098 @Manoj @ChirantanMitra4 @n1Srabani. Thank you @IITKanpur @serbonline @ANRFIndia @IndiaDST pubs.acs.org/doi/10.1021/ac…

Final version has appeared today in @ScienceMagazine :science.org/doi/epdf/10.11…