Hai-Bin Ruan 阮海斌
510 posts

Hai-Bin Ruan 阮海斌
@RuanLab
The Ruan Lab at U of MN is driven to understand Metabolic Physiology.
Minneapolis, MN Sumali Şubat 2019
401 Sinusundan361 Mga Tagasunod

Read more about the research here michiganmedicine.org/health-lab/glu…
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Congrats to @UMPhysiology PhD Student Kathryn Buscher and collaborators in the @yatrikshahlab for her first author paper in @scisignal showing that glucose and downstream GlcNAC maintains STAT3 activation and contributes to colorectal cancer tumor growth.

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#Throwback
COMMENT | @DrKristaVarady, LS Chow
Optimizing the design of time-restricted eating human trials
nature.com/articles/s4225…
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Online now: Fasting impairs humoral immunological memory by β-hydroxybutyrate-mediated depletion of plasma cells dlvr.it/TR6mcs
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🎉 🎉 Exciting new work from the Jameson and Hamilton Hart labs! Published in Nature Immunology, this study shows IL-4–STAT6 delays CD8+ T cell bystander activation by modulating IL-18 sensing, a key insight into memory T cell responses.
Read more: nature.com/articles/s4159…
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Colonic macrophage heterogeneity revealed by CD11c and CD163 mucosalimmunology.org/article/S1933-…

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@DecMcCole @NIH @AmDiabetesAssn @American_Heart @umnmedschool @UMN_IBP Thank you Declan! Look forward to seeing you again in Minneapolis in April.
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@RuanLab @NIH @AmDiabetesAssn @American_Heart @umnmedschool @UMN_IBP Congratulations Hai-Bin and Happy New Year! It was a pleasure meeting you and your group at @UMN_IBP last year.
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The @RuanLab turns 10 years today. Extremely privileged to work alongside talented and dedicated trainees and lab staff. Very grateful to my mentors, colleagues and collaborators, and of course the support from @NIH, @AmDiabetesAssn @American_Heart @umnmedschool @UMN_IBP etc.

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We are accepting applications for fall 2026 for the PhD graduate program in Physiology. Come and join an amazing group of students and faculty! z.umn.edu/ibpgradprog

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Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @Cell_Metabolism @RockefellerUniv cell.com/cell-metabolis…
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The latest from our lab in the cover of @CircRes: Macrophage-derived CCL24 exacerbates fibrosis and impairs cardiac function via CCR3. Work led by Preethy Parthiban in collaboration with Jop van Berlo's lab.
Open access:
ahajournals.org/doi/full/10.11…

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Please join us for tomorrow's IBP seminar series as we welcome Dr. McCole @DecMcCole. “Regulation of Intestinal Epithelial-Macrophage Barrier Properties by the Inflammatory Bowel Disease Risk Gene, PTPN2”

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In the latest issue! Quantifying the varying harvest of fermentation products from the human gut microbiota dlvr.it/TNC9FN
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1/11 In @ScienceMagazine: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated. science.org/doi/10.1126/sc…
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We are proud to be a founding contributor to lipidinteractome.org, a repository developed by @TheTafesseLab & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: arxiv.org/abs/2507.23101 #lipidtime
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The Verkerke lab is hiring at all levels. We apply metabolic and bioenergetic techniques to investigate how pathways are rewired in pathophysiology. Experience in bioenergetics,cancer metabolism, metabolomics, molecular biology is a bonus. Email averkerk@umn.edu to apply!
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Online now: Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity dlvr.it/TM3NYq
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The wait is over, it’s back! 🧪
Granulocyte Meeting 2025 | 15–18 Sept | Shanghai.
Big science. Big names. Big City. Don’t miss it.
🔗 g-meeting.org
#Gmeeting2025 #Granulocytes #ThePowerOfMany

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Understanding the predictors of metabolic dysfunction-associated steatotic liver disease—
Peter Crawford @ketonemics & team @umnmedschool suggest ketogenesis serves a protective role in MASLD-MASH progression via processes other than fat oxidation.
jci.org/articles/view/…

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We’re thrilled to welcome Dr. Carla Rothlin(@carlarothlin) as our new Director of the Center for Immunology and Dr. Sourav Ghosh as CFI Program director, Immunology of Tissue Resolution, Repair, & Regeneration at UMN! Both join us from Yale and officially start in August 2025.

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