Shorter Lab Members

Happy holidays from the Shorter lab!

Early View💡 "A dual-functional BODIPY-based molecular rotor probe reveals different viscosity of protein aggregates in live cells" by He Huang, Yu Liu & Xin Zhang et al. @kfzhangxin @dicp_cas @Wiley_Chemistry #BODIPY #viscosity #protein #aggregate Check👉doi.org/10.1002/agt2.3…

Multi‐Step Molecular Mechanism of Amyloid‐Like Aggregation of Nucleic Acid‐Binding Domain of TDP‐43 onlinelibrary.wiley.com/doi/10.1002/pr…

Human J-Domain Protein DnaJB6 Protects Yeast from [PSI+] Prion Toxicity mdpi.com/2014680

Roles of RNA-binding proteins in neurological disorders, COVID-19, and cancer dlvr.it/Sfb0y7

Multivalency ensures persistence of a +TIP body at specialized microtubule ends: nature.com/articles/s4155…

Mechanisms of DNA opening revealed in AAA+ transcription complex structures: science.org/doi/10.1126/sc…

A fond *fare*well to Dr.@CharlotteFare! We are excited to see what you do next @HopkinsMedicine 👩‍🔬✨

@HAntonicka you can download the submitted version with an Elsevier account

@ShorterLabGroup this paper is under review....so not accessible for viewing?

FUNDC1 Promotes Mitochondrial Translocation of TDP-43 and Modulates TDP-43 Induced Neurotoxicity papers.ssrn.com/sol3/papers.cf…

Kyla McMullen, the only Black American woman who has earned a PhD in computer science and engineering from U-M, has launched Modern Figures, a podcast that elevates the voices of Black women in computing. myumi.ch/P1Jjd | #UMichDEI

I am excited to share I have formally joined Genentech as Senior principal scientist and group lead of #singlecell and #spatialproteomics. We have several positions opening now. Dear friends, please help to spread the messages. careers.gene.com/us/en/search-r…

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation go.nature.com/3Wx1OBe This new review covers insights into the pathophysiology of ALS, advances in disease modelling, the current landscape of clinical trials and more

Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression academic.oup.com/brain/advance-…

(1/1) Proudly present our recent work on small molecule partitioning into Biomolecular condensates. biorxiv.org/content/10.110…

Attn: #HBCU #MSI faculty and trainees! Join us on January 12, 2023, for a hybrid presentation of how to bring cryoEM to your lab/institution, start a new collaboration or send your samples to one of the national cryoEM centers. @BlackinBiophys

Attn: Undergrads! Interested in biomed research? @PennMedicine offers an immersive summer research program #PennSUIP & a fantastic post-bacc program #PennPrep! 🔬🧬 To learn more, join us 1/12/23 (12-1p ET) or 1/16/23 (6-7p ET): tinyurl.com/SuipPrep #phdchat @IDEAL_research

Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus-ends: nature.com/articles/s4155…

Very pleased that our paper "Mechanistic insights into monomer level prevention of amyloid aggregation" is online now. sciencedirect.com/science/articl…