Hana Antonicka

910 posts

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Hana Antonicka

Hana Antonicka

@HAntonicka

Senior researcher in the Department of Human Genetics at McGill University in Montreal. Interested in mitochondrial biology.

Montreal/Notre-Dame-de-Grâce Katılım Ekim 2018
531 Takip Edilen973 Takipçiler
Vamsi Mootha
Vamsi Mootha@VamsiMootha·
Excited to share our new paper led by Josh Meisel w/ Gary Ruvkun. Worm suppressor genetics + biochemistry reveal that balance of frataxin and FDX2 levels is key for Fe–S cluster synthesis. Lowering FDX2 alleviates frataxin deficiency in multiple models. rdcu.be/eT5Kz
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Paulina Wanrooij
Paulina Wanrooij@PaulinaWanrooij·
Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. academic.oup.com/nar/article-ab…
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Hana Antonicka
Hana Antonicka@HAntonicka·
A great collaboration between clinical and research teams to describe mutations in FASTKD5 in patients with Leigh syndrome. Thank you all!
AJHG@AJHGNews

📣New from @HAntonicka et al! 📄Bi-allelic mutations in FASTKD5 are associated with cytochrome c oxidase deficiency and early- to late-onset Leigh syndrome cell.com/ajhg/abstract/…

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Scot Leary
Scot Leary@MitoCopper·
K1 often gets air time but this weekend K2 qualified for diving nationals! We are so proud of you Maren!! You were so close so many times at earlier meets it would have been easy to be defeated. But your determination never wavered! ❤️💪👊
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Scot Leary
Scot Leary@MitoCopper·
Taking advantage of lots of downtime at Team Sask Spring training to explore Vero Beach with @Keegan7Leary ❤️⚾️
Scot Leary tweet mediaScot Leary tweet mediaScot Leary tweet media
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Mito@GU
Mito@GU@Mito_at_GU·
New paper out from the Falkenberg and Gustafsson labs. Thanks to Pretzel for a successful collaboration. nature.com/articles/s4158…
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Martin Picard
Martin Picard@MitoPsychoBio·
The brain is full of mitochondria! But how many, and where? Different types of mitochondria specialize for energy transformation and other functions In MitoBrainMap v1.0 we provide the first maps of mitochondrial content and OxPhos capacity across the human brain
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Hana Antonicka
Hana Antonicka@HAntonicka·
@MitoPsychoBio Nice work Martin! This was all done at the level of gene expression, are you planning to look at protein levels in the individual tissues, as they not always s follow the mRNA levels?
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Martin Picard
Martin Picard@MitoPsychoBio·
All mitochondria in your body comes from the same "mother" population in the egg/oocyte, later differentiating into distinct mitochondrial phenotypes or "mitotypes" (like cell types) In the end, we are made of dozens of different specialized mitotypes New preprint where @AnnaMonzel quantifies how different mitochondrial populations are in different organs and tissues, and within the same cell type exposed to different challenges over several months biorxiv.org/content/10.110…
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