DataIsTruth

@XURA777 @zacsmithfitness @doctormorphh Melanotan2 is not melatonine

@zacsmithfitness @doctormorphh Where can I get cialis? Also what melatonin brand do u use? How long before bed? Mb for questions js building my supp stack

Boners increase T levels, this sounds insane but its actually true. If you have erectile dysfunction and you take something like tadalafil your testosterone levels restore and LH normalizes since ED suppresses GnRH. The absence of sexual activity suppresses testosterone.

@JeffVincint @looking4copes @anagenxyz @AndrewVerbinnen @Pumpfun Then how do you explain this chart. Dht reduction is needed for long term stabilization, if anything is proven in AGA it would be that

(left as a post as well) this is just speculation, not any advice, thats for everyones personal doctor, minox if taken very early and constantly most probably is potent enough. the dht-dkk pathway is really not that potent, it can be overridden fairly easily, here are the 2 components that make it so bad to everyone and no-one wants to discuss. (im not saying this is the primary driver of andro. alopecia/ its not/, we're discussing the dht/dkk pathway only, as the primary pathways are not a published cascade, overlooked) a) most likely in men, hair loss begins 2 cycles after puberty peak dht (6 years post), dht-dkk, reducing beta-c/lpr5/6 , then loss remains un-noticed until near 50% of the hair density is reduced. then men wait, it hits 60% and panic ensues. trying every topical and vitamin, then minox finally (hopefully oral) and finally the big decision, block the dht or not. by that time, its actually severe alopecia. this fits most men. dht is a component of a global cascade that causes AA. this picture in the link doesent get near enough attention. this is 1 month of a topical, that does not interact with dht (or any hormone) or the pathway at all, no minox, etc. growing terminal, hair in the most difficult area on the scalp , temporal region, review the shadow of growth. this is the area of the scalp that is claimed by the scientists to be the most affected by dht, this alone describes sufficiently that dht and removing its negative pressure is not the route. we've been decades with blinders on, following a path that has harmed far too many men. x.com/JeffVincint/st…

Yesterday: we measured how MINX enters the bloodstream in a human: 5mg oral minoxidil, lipid-matrix capsule. n=1. Single oral dose. 6 timepoints. 6 serial blood draws. Subject: @AndrewVerbinnen. Protocol live streamed on @pumpfun. Plasma minoxidil concentrations in ~1 week. Raw data + release curve published when assays return. This is how we solve hair loss.

@llana @JoseJsf22 "My point is that AI is nothing without human devs and human data." So? What do you mean by that? In any case, it's true now but will become increasingly less relevant as AI itself becomes increasingly more important in its own development

@JoseJsf22 By my logic, I’m probably not as smart as the sum of hundreds of other people. And by my logic I’m not software. AI is software and is the product of many, many people’s intelligence. My point is that AI is nothing without human devs and human data.

AI ISN’T SMART. It is software attached to vast databases of info. Without the databases, it’s not intelligent. AI is an app. Its algorithms. I’m so sick of its ignorant glorification.

@KJBoltjes @patricksavalle Jij hebt echt geen idee waar je het over hebt. Gevalletje Dunning-Kruger.

@patricksavalle Wacht even! Niemand weet volgens jou hoe die AI's precies werken maar jij weet dat de AI's die jij gebruikt wel superslim zijn. Contradictie.

Bijna niemand begrijpt AI. Geciteerde tweet is onzin. Er zit geen database achter. Het is niet zomaar een computerprogramma dat regels volgt. Een LLM is een waarschijnlijkheidsmachine. De manier waarop trainingsdata wordt verwerkt tot miljarden gewichten in een neuraal netwerk is algoritmisch ('computerprogramma'). Maar waarom een getrainde LLM tot een specifiek antwoord komt, weet niemand. Onderzoekers die dit proberen te ontrafelen (mechanistic interpretability) stuiten telkens op interne structuren die er niet bewust zijn ingestopt: circuits voor abstractie, voor planning, voor zelfreflectie. In de basis voorspelt het model een kansverdeling over het volgende token. 'Next token prediction'. Maar dat is enkel het trainingsdoel, niet wat er feitelijk gebeurt om dat doel te halen. Op een bepaalde schaal is 'gewoon voorspellen' geen geldige beschrijving meer. Zoals jouw gedachten niet meer de optelsom zijn van bio-elektrochemische reacties (en misschien quantumprocessen), en zoals Newtoniaans gedrag niet meer de optelsom is van opeenvolgende quantumtoestanden, zo is het gedrag van een LLM niet meer simpelweg 'next token prediction'. Bij voldoende schaal ontstaat vrijwel altijd (overal in de natuur zichtbaar) een emergente laag met eigen wetmatigheden. En die laag zou op een gegeven moment 'denken' of 'bewustzijn' kunnen zijn. We weten dus niet of een LLM denkt, of dat ons eigen denken óók gewoon emergent gedrag is van voorspellende materie. Op een gegeven moment maakt het ook niet meer uit. Dan is het functioneel niet meer te onderscheiden van denken, of van bewustzijn. De AI's die ik gebruik, zijn superslim. En ik zie het als denken. Beter dan mijn collega's kunnen.

@doctormorphh @kimjongthunberg It's clearly not

@kimjongthunberg Did you get a hot flush or nausea? MT-1 should be better for tanning because of better MT-1 selectivity.

The weather will be beating our ass in europe the next few weeks, if you are thinking of using melanotan-2 here is what to look out for: > Increases RHR > Can decrease appetite > Can increase blood pressure > Can increase pain sensitivity > Can get a histamine spike because of mast cell degranulation -> nausea and a hot flush. (1h or so) Yes you can take things to mitigate these side effects, that being said my favorite side effect protocol is correct dosing. 50-100mcg every 4 days was more than enough for me to get a perfect tan, with no side effects. You might have to dose a bit higher depending on the UV index, and with that in mind 200-300mcg seems like a good option as well.

@JeffVincint @looking4copes @anagenxyz @AndrewVerbinnen @Pumpfun What about dht Jeff... Minox won't work long term

firstly we have nothing to sell or offer. and more importantly, if this extended release minox. product outperforms low dose oral bid minox in their plasma study, this is going to be significant /sufficient for the majority of mild to moderate andro. alopecia sufferers. if people catch it quickly and start something like that, there is not need for our project. we are geared for more severe alopecia. finally, the ease of use of a pill is far better than a topical. its not the same patient group. ours is much smaller.

@nickmgallo @Dominic2306 @GaryMarcus No, that's not what he means.

@Dominic2306 It's highly relevant. @GaryMarcus is concerned about generalizability to other domains (central claim of tech companies, that LLMs lead to AGI). If Lean then it's not

Was it ‘pure LLM’ Gary, one of those ‘stochastic parrot’ things?! Those dastardly fascist tech bros who believed in scaling laws! 😂😂😂

@JeffVincint When will there be any clinical info? So that it is clear it's not a scam

30yo Male, (>10 yrs hair loss) this is Left Temple area, our topical project applied. this is 1 month between these 2 pictures. See the dark, pigmented, terminal hairs emerging in the temple and even above the freckle, certain hairs are hyper-induced. we expect full temporal and hairline recovery with continued application to full density, appearance. a complete reversal. (zoom well, there is much to observe in this picture)

@DeVreugd @ajboekestijn @FT So controlling 12% more of Ukraine already covers 90% of Putin's plans?

@DataIsTruth_ @ajboekestijn @FT Everything currently occupied by Ukraine, except for a part of the Donbas. In his plans, the entire Dombas was planned.

Xi Jinping told Donald Trump that Putin might ‘regret’ invasion of Ukraine via @FT ft.com/content/567c57…

@DeVreugd @ajboekestijn @FT Welke doelstellingen?

@ajboekestijn @FT Heeft (helaas) wel 90 procent van zijn aanvankelijke verkeerde doelstellingen behaald. Met het juiste gebruik van zijn schatkamer aan grondstoffen had er veel meer in kunnen zitten voor de Russen.

@MattCGallaher @JustineBateman You miss the whole point

@JustineBateman Um... you could also bring a notebook (or use the voice memo app and notes app on your phone) to take down your ideas. One could even bring a highlighter! Think of the possibilities!

"It's something that actually pierces your food in order to place this food into your mouth. It scans your plate and keeps track of how much more food there is to eat. We call it an AIFork. It's revolutionary."

@Christiano92 @pythagoras999 @GaryMarcus Only since a year ago or so, and Tesla wasn't using them either until recently

@pythagoras999 @GaryMarcus From training, validation, inference, LLM tech has invaded every part of self driving. Even the models that make up a typical self driving system (perception, prediction, planning) now use LLM like architectures.

I love AI, it’s pure LLMs I hate. Pure LLMs *are* basically just autocomplete. Recent progress (e.g. Claude Code) doesn’t show otherwise Rather, lot of the progress in the last two years has come from *introducing* other things – mainly classic symbolic techniques and tools, to offset the weaknesses of pure LLMs. Shame to see the tweet below muddle all of this. If we want to make further progress we need to understand where the progress is coming from; mostly it is coming from leaving pure LLMs behind.

@JeffVincint You can keep posting pictures and say that it will be released within 12 months, but what's the point? Build hype?

this is one of the most important pictures of our work to understand. as you zoom in the before picture, there are virtually no robust hairs on the frontal area and of to the sides. with topical application of our project only for a few weeks. you can see potent (though disorganized) follicles induced in the most difficult area on the scalp. frontal hairline. this is just the beginning this disorganized follicles over time, more and more are recruited and fill the area. from disorganized to organized. the takeaways are the full sized, even larger than other follicles, induced and growing in a robust nature, "stout". there is so much more to come.

@morellifit @Voltirie Yeah so you never had hairlos.

@Voltirie Started about 12mo ago.

Peptides > finasteride for hair loss Is it really worth having higher estrogen levels, lower libido, and a permanent dependency on this drug? Of course not. I am 44 with a full head of hair because I use these methods instead: - GHK-Cu helps rebuild blood vessels and repair follicle DNA. - AHK-Cu increases growth factors and helps reverse thinning. On top of this, I use: - Tallow butter provides an anti-inflammatory base for the follicles. - Microneedling allows peptides to get deep into the skin. - Red light therapy gives dying follicles the cellular energy they need. If you want my complete hair loss prevention protocol, comment the word "HAIR" and I'll send it to you.

@JeffVincint @takizawa2500 So we will only know when it's released?

from internal conversations, its doubtful that we will release any moa, structure info. people in biotech right now are terrified of ip loss to ai, etc. we've not even had the first court case, that will set the tone. this, as you can imagine, may be the biggest barrier to entry to market there is.

UPDATE: our topical project. (received picture, updated from previous post) with similar lighting) our topical project, 11 weeks (-3 months)of application, >25 years androgenetic alopecia nw7, (1.2mm biopsies taken offsite) growth acceleration begins at this point as the follicles have hypertrophied approx 50-60%, fibrosis potently reversing, pigmentation restored, linear velocity engaged, scalp tightness and hardness has become spongy and "healthier" feeling, though not normal yet. Still, long way to go. (updated from May 6, 2026 , ie 1 week ago) this is 12 weeks now. 3 months. application of our topical only. x.com/JeffVincint/st…

@JeffVincint @takizawa2500 When will you be able to disclose more about the science without ip issues?

yes, agreed, though most people will look at this crown area and be impressed. this is the easiest place to grow hair, for 3 months its very potent growth. the absolute most difficult place to re-grow (I know not a word) is the frontal hairline and temporal peaks.. in reality.. this before and after that is only 1 month is the most stunning growth. a single month. we anticipate to re-grow not just to an impressive level but to full density, (200+ follicles per cm2), full pigmentation to normal color, full velocity, full caliber. all of it, I realize how that sounds.

@JeffVincint @hageyoshi2323 Interesting. Do you have a first market in mind, Japan perhaps?

@DataIsTruth_ @hageyoshi2323 in every country possible. was in a meeting re Europe, there are some quarks in regulation but didnt sound like anything prohibitive.

【ダイエット中の方必見】過度な食事制限と抜け毛の関係 極端な体重減少は、医学的に「休止期脱毛症」を引き起こすことが証明されています。 ▼主な3つのメカニズム ▼ ① 生存優先の法則 摂取エネルギーが減ると、生命維持に不要な「毛髪への投資」が真っ先にカットされる。 ② タンパク質の転用 髪の9割を占める「ケラチン」が作られず、筋肉や内臓の修復にタンパク質が奪われる。 ③ 微量栄養素の欠乏 鉄分やビタミンD、特に「亜鉛」が不足し、ヘアサイクルが乱れる。 1ヶ月に体重の5%以上減らすような減量は、髪のリスクが極めて高いです。 「栄養密度」を意識したダイエットで髪も体も健康になりましょう。 #ダイエット #抜け毛

@JeffVincint @hageyoshi2323 Will it also be launched in the US/Europe?

We are currently in stealth, with a team that includes two scientists from your country. No, this is not us. our project is topical only and we remain in stealth until launch possibly end of this year or Q1 2027. We're looking for ambassadors in Japan soon. I invite you to see the pictures posted so far, these are in the bottom % of what we're seeing. its coming and its exciting!

@DoodieButthole @Tybolt333 @AgentChud It's not lmao

Bro michael jacksoned himself lmao look at his nose

@JeffVincint @jeffcafe_ All through clinical trials you mean?

@jeffcafe_ we're working, there will most probably be several routes in the coming years to effectively treat this to satisfaction.

our topical project, 11 weeks (-3 months)of application, >25 years androgenetic alopecia nw7, (1.2mm biopsies taken offsite) growth acceleration begins at this point as the follicles have hypertrophied approx 50-60%, fibrosis potently reversing, pigmentation restored, linear velocity engaged, scalp tightness and hardness has become spongy and "healthier" feeling, though not normal yet. Still, long way to go.