Springer Pathology

Whole-exome sequencing of adrenal tumors from a MEN1 patient reveals shared mutations between adenoma and carcinoma, suggesting a possible biological link - read it here: link.springer.com/article/10.100…

p63-Positive Diffuse Large B-cell Lymphoma of Oropharynx: A Treacherous Mimic of HPV-Related Squamous Cell Carcinoma—A Report of Three Cases TM Stevens, D Kokh, GP Carames, et al. rdcu.be/e2mlG #HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet

Intraductal Salivary Gland Neoplasms of the Oral Cavity: A Retrospective Case Series with Emphasis on Newly Described Entities H Alshuaibi, S Neduvanchery, SG Fitzpatrick, et. al. rdcu.be/e2mok #HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet

🚨New #EScoP course open for registration! 🪲🦠🔬We are pleased to announce a course for infectious diseases #pathology! Join us in Vienna on 22-24 June 2026! Info for programme, venue, and registration: esp-pathology.org/event/infectio… Secure your slot now!#education #PathTwitter #PathX

🧑‍🏫Meet the #ESPCongress Keynote Speakers! Cecilia Halle is part of the Ministry of Health and Social Affairs! Her talk will be Challenges and Opportunities in Pathology from a Governmental Perspective Learn more at: espcongress.org/keynote-speake… #pathology #advocacy #PathTwitter

🤝If you are attending the #USCAP2026 in San Antonio, be sure to visit the ESP booth #813 in the Exhibition Hall. We would be delighted to meet you there! @TheUSCAP #pathology #PathTwitter #PathX

A study in Virchows Archiv investigates the expression of key glycolytic markers in pancreatic cancer cells and stroma. Findings show significant differences in stroma post-neoadjuvant therapy, impacting FDG-PET response evaluation. bit.ly/4rMC9Up

Findings show that 33.3% of patients with consecutive mucosal melanoma samples exhibited different immunohistochemical results, suggesting potential molecular heterogeneity that could influence prognosis and treatment strategies. bit.ly/4seKocQ

Virchows Archiv reports on a case of T-prolymphocytic leukemia (T-PLL) showcasing three distinct abnormal T-cell subsets identified through flow cytometry. This highlights unexpected intratumoral heterogeneity in a typically uniform neoplasm. bit.ly/4bgTAre

Research published in Virchows Archiv shows that while karyotyping has limited utility in neuroblastoma, next generation sequencing provides crucial insights into genetic alterations, including high tumor mutational burden. bit.ly/4rLPVqr

Virchows Archiv discusses the importance of tailored governance mechanisms for digital pathology transformation. The proposed "Three I Framework" aims to operationalize principles for sustainable change in laboratories. bit.ly/4sSQEqH

Virchows Archiv reports on a study analyzing uncommon KRAS mutations in non-small cell lung cancer (NSCLC). Out of 4661 patients, 378 had KRAS mutations, with 14 showing uncommon variants, highlighting the need for detailed molecular profiling. bit.ly/4lLLiva

A study in Virchows Archiv assessed the Idylla IDH1-2 Mutation Assay Kit against routine methods using archival FFPE tissue and DNA from glioma patients. The analysis included 210 samples, revealing high concordance rates. bit.ly/4cWB6O0

A case study in the Journal of Hematopathology details a rare instance of primary diffuse large B-cell lymphoma (DLBCL) affecting the cauda equina in a 52-year-old woman, highlighting diagnostic challenges and symptom progression. bit.ly/3NnXxBj

The research found that higher densities of CD8+ T cells and CD68+ macrophages in sinonasal carcinoma are linked to a lower risk of recurrence. PDL1 positivity correlated with increased CD8+ infiltration, indicating potential therapeutic targets. bit.ly/4smcq6p

The Head and Neck Consensus Language for Ease of Reproducibility (HN CLEAR) Steering Committee developed parameters for evaluating invasion in carcinoma ex pleomorphic adenoma, aiming to standardize research and clinical practices. bit.ly/4bzML2T

A prospective study in @HeadNeckPathol analyzed 449 patients with oral epithelial dysplasia (OED) to identify predictors of recurrence and malignant transformation. Key findings highlight age, lesion site, and tobacco exposure as significant risk factors. bit.ly/4sUZXqe

Head and Neck Pathology reviews diagnostic challenges in thyroid pathology, highlighting pitfalls in identifying metastasis. Key scenarios include intranodal thyroid inclusions mimicking metastatic papillary thyroid carcinoma in lymph nodes. bit.ly/4dvo0aA

Head and Neck Pathology discusses the evolving landscape of sinonasal squamous cell carcinoma (SNSCC), highlighting new molecular drivers like DEK::AFF2 fusion alongside traditional risk factors such as smoking and HPV. bit.ly/3PKtJiS

This image paper details a 23-year-old woman with monophasic synovial sarcoma of the lower lip, featuring a rare MN1::SSX1 fusion. Initial tests were negative, highlighting diagnostic challenges in rare variants. bit.ly/3PfhOtq