Stahelin Lab

Candidates have been disclosed for the upcoming election for the American Society for Biochemistry and Molecular Biology. If you are an ASBMB member, don't forget to vote! #vote #asbmb #JLR #jbc asbmb.org/asbmb-today/pe…

New publication! It was a wonderful collaboration with the lab of Juan Del Valle at Notre Dame. This would not be possible without his team and their peptide design. A constrained peptide that binds the Ebola virus matrix protein #ebola #VP40 #peptide pubs.rsc.org/en/Content/Art…

I was very happy our work was chosen to the cover this month. Especially for former postdoc Souad Amiar and collaborator Andrea Marzi Cover - Journal of Lipid Research jlr.org/article/S0022-…

@RommieAmaro @SteveBrohawn @VothGroup Thank you!

@Stahelin_Lab @SteveBrohawn @VothGroup This looks very cool!

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly New preprint in collaboration with the @SteveBrohawn @VothGroup Excellent team effort demonstrating a ceramide-1-phosphate interaction in M! #membrane biorxiv.org/content/10.110…

Check out our new preprint! biorxiv.org/content/10.110… We found sphingolipid binding to SARS-CoV-2 M protein controls its conformation to coordinate viral assembly+release. Great collaboration with @VothGroup + @Stahelin_Lab co-led by @KimDolan_UCB, Mandira Dutta, + @souadamiar.

Very pleased to announce a new review in Virology put together by Ph.D. student Rokaia Sultana. This article details the strenghts and limitations of virus-like particle systems for SARS-CoV-2 #virus #sarscov2 #lipid #virology sciencedirect.com/science/articl…

@kfishbain ahh. the ole below the belt

Fines from Bears-Commanders… - Darrell Taylor received two $11,817 fines for unnecessary roughness. - Washington OT Sam Cosmi fined $11,817 for unnecessary roughness. If you watch Andrew Billings on this field goal, you’ll see why

Fatty acids and membrane order matter for assembly and budding of the Ebola virus matrix protein VP40! New work from the lab. Big thanks to Andrea Marzi! #ebola #lipidtime #membrane #VP40 #plasma_membrane jlr.org/article/S0022-…

New collaborative work examining electrostatic interactions between the Ebola virus matrix protein VP40 and the plasma membrane at key arginine substitutions! pubs.acs.org/doi/10.1021/ac… #ebola #lipidtime #VP40 #membrane #filovirus

The N (nucleoprotein) interacts with anionic lipids including phosphoinositides and phosphatidylserine. New work from the lab and collaboration with the lab of Greg Voth. #lipidtime #sars2 #membrane jbc.org/article/S0021-…

@mgupta0302 Thank you!

Great work by my lab mates on their new manuscript! They reveal insights on therapeutically blocking entry of Ebola viral particles #Ebola #virus #ATPase #therapeutic

Collaboration with Dr. Elsje Pienaar's computational lab yields a better understanding of the Ebola virus nucleoprotein's role in virus budding. #Ebola #nucleoprotein #VP40 nature.com/articles/s4200…

Collaboration with Dr. V. Jo Davisson's lab! New studies demonstrating potency and stability of diphyllin-derived Vacuolar-ATPase inhibitors #Virus #pH #fig7" target="_blank" rel="nofollow noopener">sciencedirect.com/science/articl…

Abstracts Due 5/26!🌟 Explore the latest in #Phospholipid Biology at #LSHSRC! Join Antonella De Matteis @Tigem_Telethon and @VolkerHaucke in July for "Phospholipids in Aging and Disease." Topics: lipid signaling, treatments for diabetes, cancer, & more. bit.ly/3xQj5yp

Learn more about how the Ebola virus matrix protein (VP40) dimer is stabilized! A wonderful collaboration with the Wiest and Chapagain labs integrating computational work with in vitro and cellular studies. #ebola #vp40 #lipidtime #Virus onlinelibrary.wiley.com/doi/full/10.10…

Happy this manuscript is published, especially for Ph.D. student Bali Motsa. Demonstrates how +1 or -1 in charge (and more) can alter lipid binding, assembly, and budding of the Ebola virus matrix protein VP40. #secsectitle0130" target="_blank" rel="nofollow noopener">jbc.org/article/S0021-… #ebola #lipidtime #electrostatics #VP40

@GaneshSAnand1 @anandlabpsu very nice article!

Pleased to share our group’s review of virus breathing and dynamics! Thank you ⁦⁦@anandlabpsu⁩ nam10.safelinks.protection.outlook.com/?url=https%3A%…

New work from our collaboration with the lab of Dr. Elsje Pienaar at Purdue. A computational model of the Ebola virus matrix protein nucleation-elongation process! #ebola #lipidtime journals.asm.org/doi/10.1128/sp…

New work from the lab with integrated collaborative studies with Prem Chapagain's lab on the role of phosphatidic acid in assembly and budding of the Ebola virus. @AsbmbLrd #lipidtime #ebola #VP40 sciencedirect.com/science/articl…