Tornero Lab

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Ernesto Arias-Palomo@EAriasPalomo·15 Kas

📢 El servicio de microscopía electrónica del @CIB_CSIC está buscando personas interesadas en solicitar un contrato #PTA2024. 📅 Fecha límite envío de expresiones de interés: 20/11/2024 Más info 👇 aei.gob.es/convocatorias/…

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Tornero Lab@TorneroLab·19 Kas

@NMITaylorLab @UCPH_CPR Congratulations, Nicholas!

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Louise Bang Jespersen@DKAmbNorway

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Nicholas M. I. Taylor Lab@NMITaylorLab·17 Kas

Thanks Louise, such a nice memory and a pleasure to celebrate with the Danish team. Congratulations again to the other prize winners and thanks to all current and past members of @NMITaylorLab and mentors along the way! @UCPH_CPR

Flot, flot uddeling af Anders Jahres medicinske priser 2024, med velfortjent hæder og ære til to unge forskere, Nicolai J. Weber Albrechtsen og Nicolas M.I.Taylor, begge fra Københavns Universitet - Stort Tillykke! 🇩🇰🇳🇴 @nicwin98 @NMITaylorLab @UniOslo_MED @koebenhavns_uni

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Tornero Lab@TorneroLab·16 Eyl

We're hiring! Are you looking for a PhD position in structural biology? We offer a fully-funded 4 year contract to study basic processes connected to transcription. If you're interested in joining us in sunny Madrid, get in touch with us!

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Tornero Lab@TorneroLab·10 Eyl

We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations. Read more at @biorxivpreprint: biorxiv.org/content/10.110…

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Tornero Lab@TorneroLab·12 Eyl

@VanniniLab Thanks for the useful comment! Would be really cool to observe their presence in vivo too

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VanniniLab_HT@VanniniLab·11 Eyl

Really cool! We also suspect there might be more functional partially assembled complexes in cells

We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations. Read more at @biorxivpreprint: biorxiv.org/content/10.110…

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Tornero Lab@TorneroLab·12 Eyl

@vasan06 @biorxivpreprint @asantosaledo @4k4h1g3 Thank you!! :)

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Srinivasan Rengachari@vasan06·11 Eyl

@TorneroLab @biorxivpreprint @asantosaledo @4k4h1g3 Congrats Carlo and team!!

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Tornero Lab@TorneroLab·12 Eyl

@Ella_Maru @biorxivpreprint @asantosaledo @4k4h1g3 Hi! The unique mechanism provides a strong signal for lesion repair that protects against undesired mutations in rRNA. The atomic details provided by our cryo-EM structures at several stages of the mechanism open avenues for therapeutic interventions. Hope that helps!

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Ella Marushchenko@Ella_Maru·11 Eyl

@TorneroLab @biorxivpreprint @asantosaledo @4k4h1g3 Does the unique stalling mechanism suggest potential vulnerabilities in rDNA stability that could be exploited therapeutically?

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Tornero Lab@TorneroLab·12 Eyl

@IsraelF96135088 Thank you, Isra!

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Israel Fernandez@IsraelF96135088·11 Eyl

Madrid made! Congrats!

We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations. Read more at @biorxivpreprint: biorxiv.org/content/10.110…

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Tornero Lab@TorneroLab·11 Eyl

Have you ever heard of 11-subunit RNA polymerase I? We describe a structure lacking A12 in addition to A49/A34.5!

We are happy to share our latest work on RNA polymerase I! We continued our #CryoEM study of its stalling mechanism, this time at abasic lesions, and uncovered interesting Pol I configurations. Read more at @biorxivpreprint: biorxiv.org/content/10.110…

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Nicholas M. I. Taylor Lab@NMITaylorLab·5 Ağu

We are delighted to see our review come out in @COSB_CRSB, where we review recent advances in the understanding of ion-driven rotary membrane motors. Read it here:sciencedirect.com/science/articl… @UCPH_CPR (1/5)

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Tornero Lab@TorneroLab·27 May

El pasado jueves estuvo Carlos en el #GoogleCloudSummitMadrid compartiendo nuestros últimos resultados, obtenidos con el apoyo de Alphafold, sobre complejos enzimáticos del parásito de la enfermedad del sueño: pubmed.ncbi.nlm.nih.gov/38593794/

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Llorca lab@LlorcaLab·17 May

Thrilled to share our last work @CellRepPhysSci Revealing the molecular mechanism of an anti-tumoral compound inhibiting our favourite system, RUVBL1/2 (at 2.4 Å resolution)🔥 All-@LlorcaLab work led by @CarmenBePaper and @alopezperrote Link below 👇 doi.org/10.1016/j.xcrp…

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Tornero Lab@TorneroLab·9 Nis

We are very excited to share the structure of the T. brucei MCC and a putative activation mechanism! Out now in structure: cell.com/structure/full…

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CIB Margarita Salas (CSIC)@CIB_CSIC·9 May

Nuestro investigador Carlos Fernández Tornero escribe en @abc_es en relación a las ventajas y limitaciones del nuevo AlphaFold 3. Puedes leerlo aquí 👇

La publicación de #AlphaFold3 nos trae muchas oportunidades en el campo, especialmente para los que trabajamos en interacciones proteína-ácido nucleico. Carlos da unas pinceladas sobre su gran potencial, pero también sus posibles limitaciones, en @abc_es: abc.es/ciencia/carlos…

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Tornero Lab@TorneroLab·9 May

La publicación de #AlphaFold3 nos trae muchas oportunidades en el campo, especialmente para los que trabajamos en interacciones proteína-ácido nucleico. Carlos da unas pinceladas sobre su gran potencial, pero también sus posibles limitaciones, en @abc_es: abc.es/ciencia/carlos…

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Online now! The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function dlvr.it/T5K6XD

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Tornero Lab@TorneroLab·11 Nis

Check it out! We had a wonderful time working on this challenging enzyme:

Structure@Structure_CP

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CIB Margarita Salas (CSIC)@CIB_CSIC

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Tornero Lab@TorneroLab·3 Kas

¡Damos la bienvenida a la nueva directora y vicedirectores! Agradecemos su labor al equipo saliente y tenemos muchas ganas de seguir trabajando de cerca estos años.

Damos la bienvenida a la Dra Pilar S. Testillano como nueva directora del @CIB_CSIC. La acompañarán como parte de su equipo, los vicedirectores Carmen Gil y Antonio Romero.

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