Daniel Zelmanoff

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Daniel Zelmanoff

Daniel Zelmanoff

@dzelmanoff

MD PhD neuroscientist | Visiting Postdoc @Columbia with @bjmarlin | PhD with @OferYizhar @WeizmannScience | Studying oxytocin & early-life social behavior

Israel شامل ہوئے Eylül 2015
53 فالونگ71 فالوورز
پن کیا گیا ٹویٹ
Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
New in @ScienceMagazine! 🎉 Thrilled to share my PhD project, we introduce a new optogenetic approach to study the developing brain - revealing how oxytocin shapes infant behavior. Thanks to my collaborators, @OferYizhar & my family❤️ science.org/doi/10.1126/sc… Here’s the story🧵
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Oded Rechavi
Oded Rechavi@OdedRechavi·
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has on the well-being of myself, my team, and pretty much every scientist I know (maybe you’ve noticed from my stupid jokes… :) I was exhausted of dealing with the huge delays, reviewers that can be abusive, and how arbitrary it all is. Unfortunately, the most important factors are often WHO your reviewers are and who YOU are... It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers. It can be a real difference maker if many of you join us (thousands have tried it already, but today we release a NEW and much stronger version ;) Let’s harness qed to put the power back in the scientists’ hands, to do, to read & to publish science on our own terms. I’m dying for you to TRY IT, and it’s very simple - just drop a paper (the link to the website is in the replies👇) - it’s completely secure, private, and free, and you get results fast. Please show your support, SHARE, tell your friends, and let’s be the revolution 🫵!
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Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
@iamayybee @ScienceMagazine @OferYizhar Hi Abdul! There is actually no “receiver” on the animal in our experiments. Our LEDs were designed for home-cage recording and installed above the cage, so the pups didn’t carry any hardware.
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Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
@ScienceMagazine @OferYizhar Together, these findings reveal oxytocin’s crucial role in shaping early-life bonding, and our new tool opens opportunities to explore the developing brain 🧠 This was a long journey and a true team effort!❤️ Huge thanks also to Shari Ross for her beautiful drawings!
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Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
@ScienceMagazine @OferYizhar We found that oxytocin neurons became more active during separation, and this activity was tightly linked to pups’ calls. Blocking or silencing oxytocin changed calling - not only during separation but also at reunion with the mother.
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Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
@ScienceMagazine @OferYizhar Oxytocin is famous for shaping adult bonding. But in early life, its role was unclear. We noticed oxytocin receptors strongly expressed in infancy, in both humans and mice - yet their function was unknown. We asked: how oxytocin influences pups’ cries during separation & reunion?
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Stephen Zhang
Stephen Zhang@StephenXZhang·
I am thrilled to share the published version of our study on how neuropeptide signals regulate feeding in the hypothalamus! We imaged endogenous peptide signals in subcellular compartments during behavior. Below is an updated summary: rdcu.be/dZlI3
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Megan Kirchgessner, PhD
Megan Kirchgessner, PhD@meg_kirch·
How does the auditory cortex first start responding to sounds and change over time? Come to my #SfN24 poster tomorrow (Wed) morning G1 to check out my postdoc work with @Froemkelab on longitudinal 2P imaging of mouse auditory cortex from hearing onset (P12) into adulthood!
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nature
nature@Nature·
A method that renders skin temporarily see-through could offer researchers a non-invasive way to look inside the bodies of live mice go.nature.com/3XxLC5Z
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Tallie Z Baram
Tallie Z Baram@z_baram·
Surprised & honored by the Research Award of the International Society for Developmental Psychobiology. Joining amazing prior awardees, totally powered by the fearless, innovative work of Baramlab members, present and past🙏
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Tali Kimchi Lab
Tali Kimchi Lab@Lab_Tali_Kimchi·
Our new @natureneuro paper is out! We employed circuit manipulations in transgenic WILD MICE, revealing a sexually dimorphic role of oxytocin neurons in social conflict. An admired team effort led by @ItsikSofer with our programmer Silvia Chuartzman nature.com/articles/s4159…
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Daniel Zelmanoff
Daniel Zelmanoff@dzelmanoff·
I'm so proud to share my Ph.D. work from @OferYizhar's lab, now on bioRxiv. We developed a new approach for transcranial optogenetic silencing in untethered and freely-behaving pups, exploring the role of oxytocin in early-life social behavior >> biorxiv.org/content/10.110…
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