Check out our review article describing recent updates in LAG3 biology and therapeutics in @TrendsinPharma with @jwang133 and @Curie_Bio colleagues: authors.elsevier.com/c/1lFgxbg0kscyR
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CochranLab
203 posts
Proud to have our work with @CarolynBertozzi
and Ron Levy on tumor-targeted cancer therapeutics featured in the @StanfordOTL annual report tinyurl.com/pawxhfhx; now being developed at TwoStep Therapeutics, led by lab alum Caitlyn Miller @CaitlynBioE
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Congrats to lab alum Bob Chen and the @OmniAbTech team on winning "Best in Show" at @PEGSboston for their innovative and impactful xPloration B cell/ Ab screening platform.
PEGS Summit@PEGSboston
🏆 Congratulations to @OmniAbTech , Inc. — winner of the Best of Show Award at #PEGSummit 2025! Their xPloration® Partner Access Program captured attendee votes by a landslide for its innovation and impact. Thanks to all who participated, and congrats again to the OmniAb team!
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@PEGSboston @OmniAbTech Congrats to lab alum Bob Chen and the OmniAb team for their Best in Show award at PEGSummit for the xPloration® B cell protein/Ab engineering screening cell platform!
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🏆 Congratulations to @OmniAbTech , Inc. — winner of the Best of Show Award at #PEGSummit 2025!
Their xPloration® Partner Access Program captured attendee votes by a landslide for its innovation and impact.
Thanks to all who participated, and congrats again to the OmniAb team!
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Excited to see our lab's B cell screening technology, spearheaded by Cochran alum and xCella Biosciences co-founder Bob Chen, rolled out as a now commercial instrument from antibody discovery company @OmniAbTech.
OmniAb@OmniAbTech
OmniAb Showcases Innovative High-Throughput Single B-cell Screening xPloration® Platform at the 21st Annual PEGS Boston Summit investors.omniab.com/investors/news…
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Congratulations to Professor Jennifer Cochran @CochranLab who was recently elected to the National Academy of Engineering @theNAEng for protein discovery and development, biotechnology entrepreneurship, and leadership in academic bioengineering!
news.stanford.edu/stories/2025/0…
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I'm excited to share our work "Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function" that's now out in PNAS! 1/3
Link to paper: pnas.org/doi/10.1073/pn…
Link to press release: news.stanford.edu/2024/03/11/pro…
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#JI_TopRead from @CaitlynBioE @CochranLab @CarolynBertozzi @StanfordHealth | #TLR9 agonist, PIP-CpG, enhances the CD8 #Tcell response to spontaneous tumors | #ReadTheJI #immunology #AuthorChoice #FreetoRead #TumorImmunology
👉 ow.ly/FTbV50P6FNv
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In the physiologically relevant MMTV-PyMT GEMM model, @CaitlynBioE @BarfiIdit @CarolynBertozzi demonstrated that systemic delivery of a tumor integrin-targeted TLR9 agonist (PIP-CpG) led to sustained elimination [...] bit.ly/3Cu9QTC
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Thrilled to announce that our new PIP-CpG paper is now live @J_Immunol . PIP-CpG is a tumor-targeting immunotherapy that is in preclinical development & we are hoping to advance it to the clinic in the coming years. doi.org/10.4049/jimmun… .
A 🧵👇(1/13)
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Congrats to joint @StanfordBioE PhD student @hollander_mj, @CarolynBertozzi and team for this exciting collaborative work!
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Wonderful insights and leadership from @Stanford @StanfordMed @CochranLab @KarlDeisseroth @drcwestphal
#Longwoodhealthcareleaders
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Congratulations to faculty fellows @alaurenoconnell, @CyertMartha & Jennifer Cochran @CochranLab for winning the 2022 @StanfordMedOFDD Faculty Women’s Forum Awards!
Learn more: stanford.io/3zt8wQz
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Immensely enjoyed the reviewing experience and spending the day-and-a-half on @Stanford campus with this special group of people @kumarlabucb @Widya__Mulya @chubaoyolu @TejalADesai and Darelene Soloman of @Agilent. Thank you @StanfordBioE @CochranLab for the hospitality!
Kumar Lab, UC Berkeley@kumarlabucb
Honored to serve on the External Review Committee for @StanfordBioE last week! Inspiring dept, brilliantly led by @CochranLab. Plus the views are pretty nice... Joined by @Widya__Mulya, @chubaoyolu, and @raviradhak, along w @TejalADesai and Darlene Solomon (not shown). 🌲
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Join #PEGS22 Plenary Keynote Jennifer Cochran, PhD, today at 4:10pm to discuss challenges and opportunities in developing non-antibody protein therapeutics. pegsummit.com/plenary-keynote
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TLR9 (CpG) agonist was chemically conjugated to polyspecific integrin-binding peptide (PIP) that is capable to localise various types of solid tumours as explained by Caitlyn Miller from @CochranLab at @Stanford #PEGS22 @PEGSboston
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Excited to share this collaborative work published in Cell on an exquisite drug-regulated CAR platform. Led by Louai Labanieh, jointly advised Bioengineering PhD student in the lab of @cm35c
Louai Labanieh@LouaiLabanieh
Thrilled to announce that our SNIP paper is live @CellCellPress! SNIP is a high-performance drug-regulated CAR platform that is optimized for the clinic--plans for a trial are already underway @StanfordMed. #CART #Immunotherapy #SynBio #Cancer. sciencedirect.com/science/articl… 1/
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Read Jennifer Cochran's recent @CellChemBiol article: Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression @CochranLab #AACR22 hubs.li/Q017Kf5f0
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Thrilled to share our exciting collaborative work with @CarolynBertozzi, Ron Levy, @SCIDirector Steve Artandi featured on the cover of @CellChemBiol, led by the talented @CaitlynBioE and @BarfiIdit.
Caitlyn Miller@CaitlynBioE
Excited to see our research featured on the cover of this month’s issue of @CellChemBiol. Check out our article “Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression” at dlvr.it/SCNw48 @CarolynBertozzi
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@Majzner_Lab @JTheruvath_MD Wonderful to collaborate with you on this beautiful and impactful work!
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Happy to share our lab's first manuscript. In work led by @JTheruvath_MD, we tested a combo of FDA approved anti-GD2 with blockade of CD47, a macrophage checkpoint. Blocking CD47 unleashes patients' macrophages to phagocytose or 'eat' cancer cells. Combo was highly effective! 1/
Saheli Sadanand@SaheliSadanand
📢 New in @NatureMedicine! Great work led by @Majzner_Lab @JTheruvath_MD shows that the combo of anti-GD2 + CD47 blockade ⬆️ anti-tumor activity in 🐭 models of #neuroblastoma, #osteosarcoma & #lungcancer by modulating #macrophage activity #immunotherapy nature.com/articles/s4159…
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