The Longevity Initiative

🚨 The Human Ageing Genomic Resources Are at Risk For over 20 years, our Human Ageing Genomic Resources (HAGR) have supported ageing and longevity research worldwide (200,000+ users per year, 1,000+ citations, widely used by academic labs and longevity biotech). Due to shifting UK government funding priorities, our infrastructure funding was not renewed in 2024, and these databases are now at risk of going offline. We are raising funds to cover basic server costs and secure their continuity while we pursue long-term funding. If these resources have supported your research, your company, or your thinking, please consider helping sustain them. justgiving.com/page/human-age…

Why even the healthiest people hit a wall at age 70 | Andrew Steele @statto

How could tiny breakthroughs in aging science change U.S. GDP and population growth? What’s the economic value of making 41 the new 40, or 65 the new 60? How many lives could we create or save if we could slow reproductive or brain aging by just 1 year? What would billions of healthier hours be worth to the economy, if we assume no change in the age of retirement? I spent the last two years obsessing over the design, research, and execution of this project. The result is a book upcoming with Harvard University Press, a preprint, and—maybe your favorite part—an interactive simulation tool that lets you input your own timelines and assumptions for specific breakthroughs in aging bio, then see the ROI in terms of US population & GDP growth. From @RickEcon and Jason DeBacker—the economists who co-developed the open-source, macro model that made this project possible—to extensive comments by @tylercowen, @sapinker, Richard Freeman, @NDHendrix, @ebudish, @elidourado, @geochurch, @jasoncrawford as well as interviews with 102 scientists (!) and countless iterations with award-winning designer Giorgia Lupi and the @pentagram team, we built something we hope will be a benchmark for how scientists, economists, designers, philosophers, entrepreneurs and storytellers can come together to paint, fund, and build different flourishing futures for our species. I couldn’t be more excited to share this. It’s the start of an open and evolving project—the labor and product of love, obsession, and unrelenting care. I hope you have fun playing with our simulation tool — and if you do, please share!

@statto dropped a stat we should all keep in mind: $240B spent on cancer research. $7B on aging, which causes most cancer. The math doesn't add up and the private sector can't close this gap (even Altos has limits). We need massive government investment.

We're delighted to have @statto on as our first guest of the year! In this fascinating conversation, he discusses: - Why ageing is the root cause of most modern mortality - Mortality curves, exponential risk, and what tortoises reveal about “negligible senescence” - The economics of longevity: How adding one healthy year of life could be worth $38tn to society - Why ageing research is dramatically underfunded relative to its impact Full episode here: moneymazepodcast.com/podcast/andrew… The Money Maze Podcast is kindly sponsored by @Schroders , @GOLDCOUNCIL, @IFM_Investors , and @LSEGplc #Finance #Investing #Economics #Business #Podcast #Interview #longevity #ageing