Kapahi Lab

New publication from @KapahiLab! Link here shorturl.at/MyEfV We used computational modeling on data collected during my PhD in >150 #Drosophila strains to find traits that predict lifespan and healthspan across different genotypes in response to dietary restriction. (1/3)

Really nice write-up in @Forbes by @WmHaseltine about our recent @NatureComms article. I'm excited about the potential of this work and where it will go next! forbes.com/sites/williamh…

A study in @NatureComms identifies a mechanism that contributes to how dietary restriction promotes healthy brain aging. go.nature.com/3UjCa5k

We had a fun lab outing and team building day. Making it out of the Escape room and Chinatown visit was fun with this great group of talented and fun peeps.

A study in @NatureComms identifies a mechanism that contributes to how dietary restriction promotes healthy brain aging. go.nature.com/3RXsQRu

I'm deeply saddened to share that we have lost a remarkable friend, a wonderful mentor and esteemed colleague, Judith Campisi. Judith's impact on those around her was profound and lasting. Her legacy will continue to inspire us all. Rest in peace, Judy. You will be greatly missed

Scientists found a gene called OXR1 controls brain aging when diet is restricted. Works like a traffic cop for proteins and fats, keeping things in order. Without it, age-related mishaps may increase. #ScienceNews pubmed.ncbi.nlm.nih.gov/38212606/?utm_…

Join the Kapahi Lab at the Buck Institute as a Research Associate! Unlock the secrets of the hallmarks of aging! Job Link: app.jobvite.com/j?cj=oLVYqfwO&… #sciencejobs #researchjobs @kapahi_pankaj

Join the Kapahi Lab at the Buck Institute as a Research Associate! Unlock the secrets of the hallmarks of aging! Job Link: app.jobvite.com/j?cj=oLVYqfwO&… #sciencejobs #researchjobs @kapahi_pankaj

OXR1 maintains the retromer to delay brain aging under dietary restriction 👉XR1 plays a conserved role in preserving retromer function and is critical for neuronal health and longevity. @_KAWilson_, @kapahi_pankaj nature.com/articles/s4146… @NatureComms

Scientists identify how #dietaryRestriction slows #brain aging and increases lifespan @NatureComms doi.org/gtc9b6 medicalxpress.com/news/2024-01-s…

Congrats @kapahi_pankaj & @ellerby_lisa labs! Study posted in @NatureComms ➡️how #dietaryrestriction slows brain aging and increases lifespan. Mechanism, involving OXR1, provides potential targets to slow aging and age-related #neurodegenerativediseases buckinstitute.org/news/buck-scie…

The newest work from our lab is published today in @NatureComms! We find that dietary restriction drives OXR1 expression to protect the brain with age, with potential benefits in age-related diseases! See the thread here for more details.

@_KAWilson_ presents his postdoctoral work from @KapahiLab and Ellerby lab at #BAAM2023! Kenny's work on a gene that preserves the brain with age was accepted today for publication @NatureComms!

Buck professor @kapahi_pankaj chairs the second session of the day at #BAAM2023 on aging and rejuvenation.

About to get underway at the Bay Area Aging Meeting @Stanford! The Buck is proud to be a co-organizer of this semi-annual symposium! #BAAM2023

I enjoyed doing this podcast on various topics in aging from calorie restriction to glycation

Our tiny lab worms reveal big insights! My new @eLife study shows Advanced Glycation End-products (AGEs) in processed foods caused worms to overeat. Check out! doi.org/10.7554/eLife.… @KapahiLab @BuckInstitute @ellie_elegans @theElegantWorm @AM_OMRF @americanaging @ScienceNews

The isothiocyanate sulforaphane inhibits mTOR in an NRF2-independent manner pubmed.ncbi.nlm.nih.gov/31409554/

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies link.springer.com/article/10.100…