Aging and Metabolism Research Program

Congrats to #AGE2026 Early Career Scholar Awardee Laura Quijano Sarraga (@OMRF)! Recognized by the #AmericanAgingAssociation, her research focuses on skeletal muscle aging and diaphragm fibrosis, with interests in Alzheimer’s disease and translational neuroscience. #Geroscience

Congratulations!!

Way to go, Mike! @mjbeckstead

The Lab had a great time contributing to this event and giving back to the wider community 👏🏼👏🏼

Don't forget to register for the OK Nathan Shock Center Mentorship Research Showcase! 📍 Where: Zoom 🕙️ When: March 25, 10:00AM (CST) - 1:00P (CST) 🔗 Registration: oklahoma.zoom.us/meeting/regi... For more information, visit oklahomanathanshockcenteronaging.org/mentorship-s... See you there!

For OMRF scientist Dr. Wan Hee Yoon, Rare Disease Day carries more significance than usual. It comes the same week that The American Journal of Human Genetics published his lab team’s discovery of an ultra-rare neurological disease. 🧬 Read more: omrf.org/2026/02/27/rar…

🧬 Registration for the Oklahoma Nathan Shock Center 2026 Geroscience Symposium is now open! Register here: oklahomanathanshockcenteronaging.org/geroscience-sy…

The Aging Gene Discovery (AGeD) Collaborative NSC Pilot Award submissions are due in just over a month! Don't forget to submit your application! 🔗 oklahomanathanshockcenteronaging.org/pilot-grant/

Check out the recent publication in Nature related to the effects of sterilization on lifespan. Our own Michael Stout contributed to this report from an international team lead by Mike Garratt (University of Otago, New Zealand).

🌟 Meet the AGE Board 🌟 Spotlight on Dr. Michael Stout (@OMRF) — exploring how cellular stress and metabolic pathways shape aging and influence healthspan. #AgingResearch #Geroscience #Healthspan #Metabolism #AGEBoard #OMRF

Alzheimer's disease 🧠research from the Rice lab . They have modeled how presynaptic inhibition by the amyloid precursor protein (APP) could be a key mechanism for preventing "runaway synaptic modification." @HeatherRicePhD Read the full findings here: alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Cellular deterioration in the brain begins long before someone with Alzheimer’s shows symptoms. OMRF scientist, Dr. Tommy Lewis, backed by a new National Institutes of Health grant, will explore whether this deterioration can be stopped. 🧠 Read more: omrf.org/2025/11/11/omr…

New paper in the Journal of the American Heart Association @JAHA_AHA. PFKFB2 is essential for the heart's metabolic flexibility, regulating its ability to adapt to fasting and stress, and controlling protein O-GlcNAcylation. Congrats @harold_kylene! ahajournals.org/doi/full/10.11…

Nice job, Ann!

So well deserved! Congrats, Arlan!

Our own @OMRF Investigator @AnnChiaoPhD will discuss cardiac aging today at 418pm in room 210 @AHAScience #aha25

From our own Dr. Benjamin Miller's Edward F. Adolph Distinguished Lecture: Protein and energy metabolism: a state of flux journals.physiology.org/doi/full/10.11…

Why do some people get massive gains from exercise while others see little change? 🤔 The M^3AX Trial is diving into the "Inter-individual Response Heterogeneity" to figure out how to maximize adaptations to exercise, especially as we age. journals.physiology.org/doi/abs/10.115…

The Krebs cycle is essentail for both catabolic and anabolic pathways, as well as regulating gene expression by communicating with the nucleus!

🌟 Shining bright in the world of academia! Congratulations to Kylene Harold, PhD candidate in Biochemistry, on receiving a prestigious independent F31 fellowship. @OUCollegeofMed