Scott Rothbart

Big day for the David lab! 🎉 Our @MolecularCell paper is out today- huge congrats to first authors @IfeAkano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩

@Yael_David__ @KarunaMDPhD @RichardKoche @SimoneSidoli @themazelab @qinggaochem @YangXiao_TPCB @TPCB_NYC @WeillCornellGS @MSKCancerCenter @WeillCornell Wonderful to see this out! Congrats again to Ife, Jake, Yael and team!

Thank you to our awesome collaborators, especially Rochelle & @RothbartLab, @KarunaMDPhD, @RichardKoche, @SimoneSidoli @themazelab & David lab members @qinggaochem, @YangXiao_TPCB & Nick for making this a real dream team 🫶🏻 @TPCB_NYC @WeillCornellGS @MSKCancerCenter @WeillCornell

@PVertino Wonderful news, congratulations!!

Proud to be part of the team…. a great day on Central / Western NY!

A person’s lifetime risk for #cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists published in @NatureCancer. @PospisilikJ @Bi0lilla vai.org/cancer-risk-de…

@FuksLab @CELL Congratulations, Francois! Exciting to see this story out.

Very excited to share our recent paper in @Cell, revealing an elegant mechanism where RNA modification and DNA methylation work together to regulate gene expression and influence differentiation. authors.elsevier.com/a/1kSP3L7PXqS%…

Thrilled to share the results @Cancer_Cell of years of hard work to develop classifiers for all major TCGA cancer subtypes, enabling assessment of differential drug response among cancer subtypes in clinical trials. cell.com/cancer-cell/fu…

We have postdoc positions open to study epigenetic mechanisms contributing to resistance to chemo+immuno in TNBC, and projects related to epigenetic determinants of neurodevelopmental disorders. Feel free to reach out to me here/via email. Please like and repost!

Congratulations to Van Andel Institute’s Dr. Peter Jones, VAI and @HopkinsKimmel's Dr. Stephen Baylin, and @HopkinsMedicine's Dr. Andrew Feinberg, who will receive the Harvey Prize for their groundbreaking work in cancer epigenetics! Read more: vai.org/harvey-prize

This preprint is now published with some key additions guided by an excellent review process @NAR_Open. Also grateful to our collaborators for helping progress this one across the finish line! @suscla1 @qianthefirst @Yael_David__ @zhouwanding and others! academic.oup.com/nar/advance-ar…

Manuscript acceptance (stay tuned) and a new preprint. Pretty good 24hrs for the lab! biorxiv.org/content/10.110…

@Govind_Lab @MolecularCell Thank you, Chhabi! Hope all is going well.

Online Now: DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states dlvr.it/TGZ732

@Yael_David__ @MolecularCell Thanks, Yael! And same to you for your new exosome story.

@RothbartLab @MolecularCell Congratulations Scott!! Elegant work as usual 🤩

@KJArmache @MolecularCell Thanks, KJ!

Congratulations to the authors @RothbartLab, shows the role of UHRF1 in the redistribution of H3K9me3 following DNA hypomethylation, a lingering question in the field and may have implications for the field of aging. cell.com/molecular-cell…

Two new papers from the lab to end the year! Will be posting about them both at the new place in the coming weeks. @rothbartlab.bsky.social Come join us - it’s great! #SciCommBackAgain

@helin_kristian @helink Also made the move. It’s becoming reminiscent of the good ‘old’ days of ScienceTwitter over there. Come join us! @rothbartlab.bsky.social

Time to move. See you all on Bluesky: @helink.bsky.social Let's work on getting our respective institutions and our colleagues to move as well. There is an exponential increase in members on Bluesky!! theguardian.com/media/2024/nov…

@BurtonNick Congratulations!!

If you are interested in a faculty position in the heart of metabolism, at one of strongest and most supportive institutes focused on metabolism, epigenetics, neurodegeneration and more, VAI is recruiting at all levels! vai.wd1.myworkdayjobs.com/en-US/VAICaree…