Eva D B Fain, BSN MPH RN CDE, CHES

SHOULD SAY GENETICS. I over wrote the buffer in X again. I have no need to get a blue check. again. I am on linkedIn & facebook... seriously the blue check became meaningless almost 2 weeks after Musk introduced it.

@MichaelMindrum Dr. Hall had reached an endpoint. My view obviously. He could not go forward as his training was in physics, not physiology or human biochemistry. @davidludwigmd is circling around the concept of satiety. This is the key to obesity.

@Paul_Wischmeyer i WONDER WHERE I MIGHT BUY REAL CREATINE? sorry about the caps. I get the FDA & other newsletters to see what my government is doing. They have busted some fake drugs sold in health food stores. Medical grade supplements are needed over the counter?

A SINGLE 20g dose of creatine increases cognitive processing speed by 24.5% within 3.5 hours. A placebo-controlled trial found that creatine rapidly enhanced brain bioenergetics & improved cognitive performance during sleep deprivation, with effects lasting up to nine hours.

A poor diet remains a leading contributor to ischaemic heart disease, according to an analysis published in Nature Medicine. The authors estimate that suboptimal diet was responsible for more than 4 million ischaemic heart disease related deaths. go.nature.com/4m5rfbi

The epidemiology of GLP-1 medicines-suggestive protective associations with reduced rates of respiratory diseases and serious infections require further confirmation jamanetwork.com/journals/jaman…

"Left to its own devices, my mind spends much of its time having conversations with people who aren’t there." ~@ANNELAMOTT

yes! an awesome metaphor for how we live.... or how some of us live. others live online to be snarky at others. my nemesis showed up in my life.... he agreed to stay 10 feet away from me in writing. It will not be pleasant if I call the police on him.

“If you want to make God laugh, tell her your plans.” ~@ANNELAMOTT

“There is ecstasy in paying attention.” ~@ANNELAMOTT

@AnneLamottQuote @ANNELAMOTT i liked a couple with her mom I sat with recently.... however, her hubby started in on Trump's sex life. I had to move to a table by myself... yuck, Trump's sex life.

“Some of the loneliest, most miserable, neurotic, despicable people we know have been the most successful in the world.” ~@ANNELAMOTT

i rather like that line. thank you @annelamottquote

FUN? I still get some weird come-ons in bars/coffee bars/social events. someone looking at me & saying, "wow you are actually pretty"? "you remember everything you read"? yes, dude, I especially like men treating me like I am a FREAK in social settings.

t2d.hugeamp.org to organize all the BIOCHEMICAL information is a massive project. understand the genetic is mind boggling. does the world need EVERYONE using up electricity & creating heat to find answers? do we need to all duplicate same work?

false sense of security with usage of sunscreens? is it lifetime sun exposure? lack of heritable skin pigmentation? FYI Africans with dark pigmentation do get skin cancer open to discuss. Bring your references! pubmed.ncbi.nlm.nih.gov/30205563/

When we discovered irisin in 2012 (Bostrom et al), we described its actions in terms of the browning of the white fat and anti-diabetic effects. Here, in collaboration with the Mathis lab, we re-examine this in mechanistic detail. nature.com/articles/s4225…

considered investigational & undergoing clinical trials..? pbs.org/newshour/healt… SPEEDY APPROVAL.... here it comes... what? the nausea, vomiting, diarrhea, gallstones.... same scenario I get from high fat.

best troll response to @caloriesproper2 we need to offer online rewards... pictures of carrots? THANK YOU FOR SPEAKING UP @MelmontC

seriously @caloriesproper2 although I tend to agree the light spectrum may be important; extinction level event is a bit over the top verbiage. please post research. You probably can but do not. you seem to be intent on picking fights with others.

Friday? I get emails from folks who are collecting research on obesity, diabetes, & connected via LinkedIn with others who post ketogenic metabolism research. I am exhausted from people suggesting I eat high fat. as I cannot tolerate it PERSONALLY.

🐭New Nature Metabolism study (2026) identifies a novel immune-metabolic pathway by which irisin which is an exercise-induced myokine. It reduces obesity and insulin resistance in mice.🐭 🏃 Irisin is released during exercise, cleaved from FNDC5 in muscle 📈 Irisin overexpression in HFD-fed mice: reduced obesity + improved insulin sensitivity 🟢 Irisin increases IL-33 in white adipose tissue 🛡️ IL-33 preserves ST2+ regulatory T cells in adipose tissue 🔬 Adipose regulatory T cells suppress inflammation → metabolic protection Exercise reshapes the immune microenvironment of fat tissue. IL-33/T cell signaling may be a new therapeutic target for obesity-related insulin resistance. This adds a bit more basic science to understanding obesity and metabolic disease as fundamentally an issue of immune dysregulation. 🏁 doi.org/10.1038/s42255…

discuss with @MichaelMindrum yes.... we have to turn all of life upside down to get to the reality of metabolic disease.... this sounds helpful... I have under the radar (obviously not) tasks to complete in the next 2 weeks...