Dessimoz Lab

FastOMA is out now in Nature Methods 🎉: nature.com/articles/s4159… A new orthology inference algorithm that scales linearly and is highly accurate. FastOMA can process all >2000 eukaryotic UniProt ref proteomes <24 hours 🚀. Try it out at github.com/DessimozLab/fa…

From @SinaMajidian, @DessimozLab and colleagues, FastOMA achieves fast and accurate orthology inference, with linear scalability. nature.com/articles/s4159…

OMAnnotator: a novel approach to building an annotated consensus genome sequence doi.org/10.1101/2024.1… Automatic identification and annotation of MYB gene family members in plants doi.org/10.1101/2021.1…

In this exciting new preprint, Warwick Vesztrocy et al use Bgee to show that "the most diverged orthologues display the greatest change in gene expression, thus suggesting that they have a greater functional divergence" biorxiv.org/content/10.110…

Exploring gene duplications! Our study reveals how duplicated genes diverge in function using structural and expression analysis across 36 species. Check out our paper: biorxiv.org/content/10.110… Thanks to @the_alexwv, @Gloveface, Paul Thomas, @cdessimoz #Genomics #Evolution

Session 24: OMA/OMArk is starting now! To join in the session, jump over to our discord at: discord.gg/gF73fCF4 Or you can join in on the YouTube stream at: @thebiodiversitygenomicsacademy" target="_blank" rel="nofollow noopener">youtube.com/@thebiodiversi… @SinaMajidian @OMABrowser

Learn more in this blog post by Charles Bernard, first author of the work: lab.dessimoz.org/blog/2024/08/3… And link to the preprint of course: biorxiv.org/content/10.110…

EdgeHOG is now available on GitHub github.com/DessimozLab/ed…. Whether you’re working with a small clade or a large phylogeny, you can now perform ancestral gene order inference with ease. Try it out and let us know how it goes. #OpenScience #GitHub

For evolutionary biologists interested in tracing genomes back to their ancient ancestors, we’ve developed EdgeHOG—a tool that reconstructs ancestral gene orders at an unprecedented scale and speed. #Genomics #EvolutionaryBiology #EdgeHOG Thread!

Many interesting discussions at the #ISMB2024 poster sessions. Thanks to everyone who stopped by our poster and to #ISCB and @DessimozLab for the opportunity!

With a nice photo of lab alumnus @leomrtns !

nature.com/articles/s4155… Have a look at the article I reposted by @BallouxFrancois, @cedriccstan and @LucyvanDorp if you're interested in viruses and their evolutionary signature when jump hosts. I had the pleasure of writing a news and views piece about this work with @cdessimoz

Quality assessment of gene repertoire annotations with OMArk go.nature.com/4bH5OaF

📢 Glad to share our piece 'AI and the democratization of knowledge' @ScientificData. Data is the new oil—ripe for reuse. But what does it take to reuse? it's about making data interpretable by all, including AI, the ultimate non-specialist! #OpenScience nature.com/articles/s4159…

📢CALL FOR ABSTRACTS📢 🌟Abstract submission is now open for the Quest for Orthologs meeting #QFO8 which will be held at the University of Quebec in Montreal, Canada on July 17-18! More info at event.fourwaves.com/qfo8 Deadline: April 26.

How to evaluate the quality of a genome annotation? Introducing #OMArk, a groundbreaking tool by SIB’s @Why_Nevers & @Dessimozlab and part of the SIB Resource #SwissOrthology, now featured in @NatureBiotech: nature.com/articles/s4158…

Our OMArk paper is finally out at @NatureBiotech! I am excited to share the final results of our work with @Gloveface @cdessimoz @VictorRossier @DessimozLab. OMArk is a one-stop shop for eukaryotic genome annotation assessment. Link : nature.com/articles/s4158… (🧵)