Laurence Ion 📍 Viva.city

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Laurence Ion 📍 Viva.city

Laurence Ion 📍 Viva.city

@longevion

Building a new city for people who want limitless health in our lifetime: ⁣ @CityOfViva ⛲️ ⁣ Also co-created @VitaDAO, @JellyfishDAO, Zuzalu, Vitalia

San Francisco, CA انضم Haziran 2011
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Laurence Ion 📍 Viva.city
Laurence Ion 📍 Viva.city@longevion·
Building such a moonshot is hard. Chances should improve with a good co-founder. This is very valuable to me, and I want you to be rewarded if you help spread the word and find the right person.
Viva.City@CityOfViva

Help us find a cofounder for @longevion to build @CityOfViva Our mission: make death optional for most people by 2040 If you introduce the right person → $100K If you spread the word to someone who does → $50K (the whole referral chain gets a piece) Details ⬇️

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Adam Gries
Adam Gries@adamgries·
Let’s stay at peak health without limits! 🧬 Vitalist Bay 2026 is T-30 days away in Berkeley, CA from May 14-17. Thanks to our partners, join this week & get: 🩸 Free @rythmhealth blood panel 🩻 Free @BodySpec DEXA scan Full program @ vitalistbay.com (+ a unique benefit ↓)
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Laurence Ion 📍 Viva.city أُعيد تغريده
Viva.City
Viva.City@CityOfViva·
The Limitless Pill?
Paul Kohlhaas bio/acc@paulkhls

🧵 Over 24 hours, our scientific team and AI scientist infrastructure developed a novel peptide agonist to potentially treat ADHD. Below is our paper for a pre-IND computational feasibility assessment for OX2R-004: an 18-residue peptide agonist designed as a selective OX2R agonist for ADHD. Why this matters? No approved orexin agonists exist anywhere. All marketed orexin drugs are dual OX1R/OX2R antagonists for insomnia. Clinical-stage ones are small molecules for narcolepsy only. We did this with @peptai_ a novel full 8-gate computational pipeline in one shot developed by @BioProtocol community 👇

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Laurence Ion 📍 Viva.city أُعيد تغريده
Brian Armstrong
Brian Armstrong@brian_armstrong·
Aging is arguably the root cause of most major diseases. Our cells lose function as we age, allowing various conditions to manifest, which is why most major diseases correlate with age. Yes, it is more complex than this, but this is a major component. @newlimit is working on treating a root cause of disease (aging) using epigenetic reprogramming.
Brian Armstrong tweet media
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Anthony Duca
Anthony Duca@Anthonyduca·
@brian_armstrong @newlimit TL;DR. Just eat whole foods, exercise, sleep 6-8hrs, meditate and breathwork daily. That is the longevity protocol that you need. The rest of this, it’s optimization on top of that.
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Anis ⚡️🦾
Anis ⚡️🦾@anis_neyo·
introducing Chargebotic, autonomous charging for robots. robots are getting smarter every day. but they all share the same problem: someone still has to charge them. designed for space to charge and save rovers on the Moon, we realized robots on Earth have the same problem. Chargebotic is a simple, universal charging system. it includes a charging pad, a receiver module, and software that manages your robots' charging. this allows your robots to charge themselves anywhere in extreme environments, across entire fleets, and across every robot brand. currently working with our own robot, Spark-E. testing with more robot types coming soon. sign up for early access link in bio.
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Laurence Ion 📍 Viva.city أُعيد تغريده
Bryan Johnson
Bryan Johnson@bryan_johnson·
I think peptides are popular because they give people a feeling of power and control. One feels helpless when they can't sleep, stop scrolling, eat well or exercise consistently. A few injections wrestles back a feeling of control. Evidence shows that injections amplify perceived agency (the ritual potency of administration). This creates a dangerous situation where powerful compounds are being used less for biomarker improvement and more for psychological wellbeing. This is what you want: closed loop. > intervention (peptide) > biological change > measured biomarker > adjustment How most people are using peptides: open-loop. > intervention (peptide) > subjective feeling > more intervention The open-loop compounds over time. Without biomarker feedback, dose escalation is driven by subjective feelings which creates increased risk of doses with no clinical precedent. I am pro peptide and pro experimentation. Some peptides such as GLP-1s and similar are among the most effective in the world. Peptides (without clinical data) are among the most promising therapies available. They also need more clinical work so that we can characterize their effects, both good and bad. Nothing is free in biology.
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Laurence Ion 📍 Viva.city أُعيد تغريده
VitaDAO 💛
VitaDAO 💛@vitadao·
.@LifeRubedo, backed by the VitaDAO community, just reported positive Phase 1 results for RLS-1496 First-ever drug targeting GPX4 to selectively clear senescent "aged" cells, tested in humans After just 4 weeks of topical treatment: • Senescent cells reduced • Psoriasis improved (statistically significant) • Itch reduced in atopic dermatitis (25% of patients vs 0% on placebo) • Collagen production increased in aging skin • Well-tolerated, no serious side effects A second US trial in precancerous skin lesions is underway. Oral formulation in development. biospace.com/press-releases…
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Laurence Ion 📍 Viva.city أُعيد تغريده
Viva.City
Viva.City@CityOfViva·
US government killed a $100m investment in @davidasinclair 's company because they believed a foreign power would gain too much access to age-reversal research !!
John Cumbers@johncumbers

A foreign government attempted to invest over $100 million into one of David Sinclair's age-reversal companies. The US government BLOCKED it. The reason? They classified the technology as too dangerous to fall into foreign hands. Sinclair sits on the board of the company. He confirmed the investment was killed because the US government believed a foreign power would gain too much access to age-reversal research. When asked if it was China, his response: "I won't say more. It's sensitive." But here's what he DID say: Governments around the world are watching this technology closely. Not just for healthcare. The US government has identified what Sinclair calls "so-called super soldier potential" in age-reversal tech. He also said the winner of this race won't just gain economic advantage. There will be "potential for radical change in the pharmaceutical industry, in healthcare" and dramatic social change. Sinclair believes the technology is very powerful and that society should start preparing now. Because as he put it: "It's not an if. It's a when." David Sinclair is at SynBioBeta this year - discussing the science of slowing and reversing aging. Link for tickets below. — @davidasinclair

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Laurence Ion 📍 Viva.city أُعيد تغريده
Viva.City
Viva.City@CityOfViva·
Let's help humans too! Over-regulation is killing millions, and, eventually, billions of people
vittorio@IterIntellectus

ok so the rosie story was even more insane than it looked > be the australian tech guy who made a cancer vaccine for his dog > first try: genetic algorithms to design a new drug from scratch > works in simulation but would take years to test > second try: screen 1 million existing compounds against the mutation > two weeks of computation. find a perfect match > it's patented > patent holder says no to compassionate use > what_did_you_expect.jpg > spend two weeks just being with the dog > 2am idea: what if i just make a vaccine > chatgpt for pipeline, gemini for construct, grok for validation > 300 gigabytes of raw sequencing data to half a page of vaccine construct > university ethics approval would take until mid-2026 > dog doesn't have that long > panik > canine cancer expert connects him to a lab in queensland with existing approval > drive 14 hours to get there > inject > three weeks later the tumors swell. immune system swarming > six weeks later shrinking > two months later legs returning to normal > one mass doesn't respond > sequence it again > different cancer. the vaccine worked. the body grew a new tumor he's now building a company so every dog owner can do this he had the technology the whole time. he spent 18 months fighting for permission to use it

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Laurence Ion 📍 Viva.city
Laurence Ion 📍 Viva.city@longevion·
@CityOfViva The standard way is so much slower than what’s possible. Vaccines usually take 15 years to get to market. What’s possible is a few months (with the same or better safety standards, and continuous long term monitoring!).
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scoopy trooples
scoopy trooples@scupytrooples·
@bryan_johnson who has an ego death spiritual experience and comes to the conclusion that they want to live forever?
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Bryan Johnson
Bryan Johnson@bryan_johnson·
This was the most profound experience of my life. I am stunned beyond comprehension. This molecule is without peer. The 27mg dose opened up what felt like pure consciousness and intelligence. A majestic reveal of existence itself. In all its incomprehensible glory and majesty. It is impossible to explain with words. Whatever you imagine, multiply it by 1,000 and then add infinite width and depth and dimensions. But entrance was not granted without prerequisite. Existence demanded that I submit. That I say yes; without attachment and without condition. Yes to existence; yes to the dissolution of self; yes to release control; yes, to all. My ego registered the ask and panicked. It wanted control. It was desperate for control. It pleaded to escape from the torrent of light and essence that threatened to rip my sanity into chards. The urge to eject was overwhelming. Terror thundered throughout my mind and body. It took everything within me to release. I overcame and was treated with bliss that defies imagination. A euphoria colored with perfect harmony of all things. An orchestra of essence washed over me and swept me up in dance. It was home. The highest aspiration of intelligent life. For some reason, stored and tucked away as the ultimate prize. A single concept emerged in omnipresence: we cannot grok the preciousness of our existence. Yet it is everything we’ve ever wanted and more. The state we long for without knowing it exists. This caused me great pain and heartache. A swell of loyalty and devotion emerged inside me, pledging allegiance to existence. To become a warrior and caretaker of life on earth. To protect at any cost the candle of consciousness that has miraculously emerged in this part of the galaxy. What awaits will wipe all your tears, soothe all your sorrows, and infinitely exceed your wants.
Bryan Johnson@bryan_johnson

twitter.com/i/broadcasts/1…

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Aris
Aris@aris_segueg·
800k people raged on my last video, here's what they missed 1) Say something polarizing 2) Let the internet rage. That's free distribution 3) Show the real product while they're watching Seasons is live, @celine_grooms let's show them
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اكتشف

@adamgries @rythmhealth @BodySpec @brian_armstrong @newlimit @Anthonyduca @anis_neyo @bettslacroix