Marc Daniels 🇺🇸
9.1K posts

Marc Daniels 🇺🇸
@mpauldaniels
The best is yet to come. I enjoy American manufacturing (https://t.co/bfqSPuq5q8) and football (https://t.co/Tj1Lhpc8t9). Profile = bookmarks etc.


Everyone's talking about retatrutide for weight loss (28.7%). Almost nobody's talking about what it does to your liver. More than 80% reduction in liver fat. Over 90% normalization rates. In a body composition substudy from the Phase 3 program. 100 million Americans have fatty liver disease. Most don't know it. There's no FDA-approved treatment for it besides "lose weight and hope." Retatrutide's glucagon receptor activation appears to directly target hepatic fat metabolism not just as a side effect of weight loss, but as a primary mechanism. This isn't a weight loss drug that happens to help your liver. It might be a liver drug that happens to cause weight loss. Phase 3 weight loss data drops first half of 2026. Watch this space.



ONE SHINING MOMENT 🙌 #MarchMadness

@pitdesi will take the bet that no SF based company founded after March 2020 until today that raised VC capital will exit above $10b.






There’s been a lot of allegations against Delve. But we haven’t been able to share our side of the story until today due to ongoing cybersecurity and forensics investigations. Maintaining customer trust is central to everything we do. That said, we grew too fast and fell short of our own standard. To our customers, we deeply apologize for the inconveniences caused. We take these allegations seriously and have made changes: a new auditor network, free re-audits and pentests for all customers, enhanced transparency in audit communications, and more. However, we also want to set the record straight on the anonymous attacks. The evidence we have points to a targeted cyberattack from a malicious actor, not a “whistleblower.” We believe the attacker purchased Delve under false pretenses, exfiltrated internal company data, and used it to launch a coordinated smear campaign. The posts rely on a mix of fabricated claims, cherry-picked screenshots, and stolen data taken out of context. See the link in the comments for more details. Delve was built to modernize compliance. We are not going anywhere and are committed to building what's next.


as someone who has kinda spent a little bit of time with MRR graphs...this is terrifying. it's less about pure $-amounts and more about trends/trajectory. the speed at which the growth *changes* is existential and implies that this graph will have a downward slope in < a month







The Codex App is now our most used surface, ahead of the VS Code extension and the CLI. No wonder it inspires a few others 👀 You can install it here openai.com/codex/ + you get up to $500 in credits if you are getting started as a business or enterprise.

















