Charlotte Brierley
375 posts
@CKBrierley
Academic Clinical Lecturer in Haematology @MRC_WIMM, @OUHospitals, Oxford. Previously @PapaemmanuilLab, NYC. Interested in all things myeloid and BMT.
Terrific Ernest Beutler honorific lecture session #ASH25 by @mpdrc and Radek Skoda on discovery of JAK mutations and development of JAK inhibitors. Generous to collaborators in the #MPNsm community and key role of patients, very classy. And the room was such lurid green ala #Wicked that I was waiting for someone to start soaring around on a broom and singing “Defying Gravity”! 🧙 🤪
Huge congratulations to Amir Fathi for delivering one of the most impactful plenary presentations @ASH_hematology in AML in past decade. The PARADIGM study may lead to a Paradigm shift- Aza/Ven > intensive chemo in newly Dx high-risk AML. 👏👏👏
🚨🚨Paper out! 🚨🚨 Delighted to share our work, now published in @NatureGenet 🧬! shorturl.at/94s5S We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n 🧵👇
