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Interested in how DNA HYPO-methylation records cell histories? Check out our new pre-print! Big congrats to first author @TJSScott and co-authors @hansen_tylerj @EvonneMcArthur biorxiv.org/content/10.110…
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The Hodges Lab
96 posts
The Hodges Lab
@Hodges_Lab
Research group in Biochemistry and Human Genetics at @VanderbiltU - Our research strives to understand how epigenetic features shape human genomes 🧬🧫🔬
Nashville, TN Beigetreten Ağustos 2019
225 Folgt406 Follower
The Hodges Lab retweetet
Excited to be part of this exciting initiative in systems biology, data science, and AI:
news.vanderbilt.edu/2025/01/16/new…
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The Hodges Lab retweetet
Achievement Unlocked! @huihuian521, our 1st PhD student’s 1st 1st-author paper! Out now in @MolecularCell 🧵
We identify the 1st m6Am Reader and uncover a novel and unexpected mechanistic role for this abundant yet enigmatic mRNA modification. (1)
cell.com/molecular-cell…
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A very interesting study, very-well presented in today’s webinar!
The Hodges Lab@Hodges_Lab
In this new preprint, we do a deep dive into the temporal relationship between DNA #methylation, #chromatin and #enhancers. Amazing work by first author @GuerinLindsey and thanks to our collaborators @IhrieLab, @KenLauLab, & biomodal. biorxiv.org/content/10.110…
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The Hodges Lab retweetet
The Center for Computational Systems Biology at Vanderbilt is conducting a search for junior faculty (s) in the field of computational biology. It is a great opportunity for young investigators to tap into relatively large human data resources here.
nature.com/naturecareers/…
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The Hodges Lab retweetet
First preprint from the lab 🚨
How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process?
biorxiv.org/content/10.110…
(1)
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@Ella_Maru @GuerinLindsey @IhrieLab @KenLauLab Great question! We may need higher resolution of 5-hmC timing to know the answer for sure (not to mention a more direct measure of enhancer activity) but it's certainly possible.
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@Hodges_Lab @GuerinLindsey @IhrieLab @KenLauLab Could early 5-hmC predict enhancer activation windows, particularly in lineage-specific contexts?
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In this new preprint, we do a deep dive into the temporal relationship between DNA #methylation, #chromatin and #enhancers. Amazing work by first author @GuerinLindsey and thanks to our collaborators @IhrieLab, @KenLauLab, & biomodal. biorxiv.org/content/10.110…
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@Hodges_Lab @GuerinLindsey @IhrieLab @KenLauLab Sounds very interesting, congratulations all and look forward to a read!
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@Hodges_Lab @GuerinLindsey @IhrieLab @KenLauLab Congrats Emily and team! This looks amazing! Can't wait to read it. 🥳
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The Hodges Lab retweetet
The version for *posterity* is out @NAR_Open! Congrats to lead authors @AnaMonteagudo4 & @jrichardalbert, our friend/collaborator @DaanNoordermeer & engineer extraordinaire Margherita Scarpa! Findings largely intact, but short 🧵 on changes since preprint academic.oup.com/nar/advance-ar…
Maxim Greenberg@maxvcg
🚨New Preprint🚨 In this study, we set out to determine how the de novo DNA methylation program impacts the 3D cis regulatory landscape. Comments welcome! Here's a thread detailing our study's key findings (1/12) biorxiv.org/content/10.110…
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Congratulations Dr. @TJSScott on your successful defense and stellar presentation of your recently published work on DNAme patterns as cell histories rdcu.be/do1Ij
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The Hodges Lab retweetet
Don't forget - Tim Scott from the @Hodges_Lab will be defending his thesis tomorrow (Wednesday, Nov. 15th)! 1:00 PM in 214LH!
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The Hodges Lab retweetet
Hi all, we just dropped version 2.31.1 of bedtools, which addresses some compilation issues encountered with GCC 13. Many thanks to @jomarnz for the key patch and for the many users who reported this issue!
github.com/arq5x/bedtools…
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Nashville friends - what are your favorite restaurants and must see spots?
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The Hodges Lab retweetet
CONGRATULATIONS 🎉 to all our graduates who walked at yesterday’s #VU2023 ceremonies, and to all those who graduated but didn’t walk! 🍾🎉
📸: @hansen_tylerj, @Hodges_Lab, @Poke_PhD, @Topo_Lab, @Kevin_Childress, @CassandraAwgu, Megan Aumann
#vandygram
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The Hodges Lab retweetet
This week's special edition of the Frontiers Seminar Series will feature our very own @alexmblee and @hansen_tylerj, both recipients of prestigious departmental awards! Join us Friday at noon in LH 214, light refreshments will be provided beforehand.
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The Hodges Lab retweetet
Only 4 days left to submit an abstract for a short talk consideration at our SDB Enhancer symposium on July 20 in Chicago. We have an exciting lineup of invited speakers: @LCochella ,@EKFarley ,@Hodges_Lab , Yana Kamberov, @MustafaMir16 and Alex Nord #2023SDBEnh @aburger2009
Society for Developmental Biology@SocDevBio
The Satellite Symposium Outside of Exomes: Enhancers in Development and Congenital Disorders at #2023SDB in Chicago is accepting abstracts for short talk consideration (separate of the main meeting). Abstract deadline: April 10, 11:59 PM ET. #2023SDBEnh kvonlab.org/sdbenhancer
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