Valery Krizhanovsky

@IdoWolf1 Ido, this a specifc drug for a specific, and rare, mutation. It is not relevant to other p53 mutations, which are, of cause, a major problem in cancer. This is a great breackthrough, but from here to millions is unfortunately a long way to go.

כולם עסוקים במהפכה באיראן תהיה או לא תהיה וכמה אולי ימותו. אבל לפני שבוע היתה מהפכה אמיתית, מוכחת, יוצאת דופן, שעוד תציל מיליונים. אבל מהפכה אופטימית קצת פחות מעניינת. מקפיץ שוב את הציוץ. זה באמת הרבה יותר חשוב לאנושות.

@AgingBiology 12 years ago - Cell fusion induces senescence through polyploidy, DNA damage Cell fusion induced by ERVWE1 or measles virus causes cellular senescence - PubMed share.google/P0zeAbEBCYTD8J… Cell fusion induced senescence - PubMed share.google/Ag0MLjqkcJgOGD…

Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer? aging-us.com/article/206355…

@NirBarzilaiMD Congrats Nir!!!

I am honored to have been elected to the Association of American Physicians (AAP) — one of the highest honors in academic medicine. AAP membership is limited to 70 physician-scientists per year and recognizes outstanding contributions to biomedical research. 🎉 What this means for the field of Geroscience is that it is finally being accepted by the more established fields of medicine. I consider this good progress! I would like to express sincere thanks to all who have taken part in my journey — sharing ideas, encouragement, laughter, and fun.

@IdoWolf1 לא בטוח בכלל שזה לא ארטיפקט

מדובר רק בתאים במעבדה, לא ראיתי שחזרו על התוצאות, לא הייתי מסיק מכך כלום על בני אדם עדיין. פשוט מעניין.

מאמר לא חדש אבל מרתק. מוזיקת מטאל גורמת לתאי סרטן קיבה לשגשג, אבל מוזיקה קלאסית- לא. איזו מוזיקה לדעתכם.ם הכי מסוכנת? link.springer.com/article/10.100…

@ToiberDebbie Beautiful work. Congrats Debbie!

SIRT6 decline throws Off Mood, Sleep, and Cognition. rdcu.be/eTvJj Tryptophan byproducts build proteins, NAD+, and neurotransmitters (serotonin and melatonin). Yet, in aging and neurological disease, this balance is lost, leading to impaired mood, learning, and sleep.

🚨 New today in @ScienceMagazine !!🚨 We’re publishing the results of the largest AI persuasion experiments to date: 76k participants, 19  LLMs, 707 political issues We examine “levers” of AI persuasion: model scale, post-training, prompting, personalization, & more… 🧵:

How to identify persistent senescent cell with increased resistance to apoptosis? Check our latest preprint with spotlight on cell surface v-type ATPase ATP6V1B2.. @NatalyFreizus @KrizhanovskyLab @UriAlonWeizmann biorxiv.org/content/10.110…

A few weeks ago, I heard the Philharmonic perform in New York, and outside there was a demonstration. It was after the ceasefire, and the people there weren’t protesting Gaza. The signs we saw weren’t about Gaza at all. They were about Israel - about the existence of Israel. The charade is over. It’s now completely clear that to protest the Philharmonic in Paris by lighting torches, at a moment when Hamas and Israel have already agreed to a ceasefire, is not about stopping the bloodshed. It has nothing to do with humanitarian concerns. It is about hatred. It is about inciting the destruction of Israel. It is about trying to delegitimize anything connected to Israel. What we are seeing is one of the most ambitious and radical projects of our time: an effort to indict Israel in a way that makes its very existence impossible, and any violence against it - against its citizens or its institutions - morally acceptable and even justified across intellectual and political life. This is a project to incite a new war. x.com/visegrad24/sta…

"It's just a temporary space until your lab is renovated", Weizmann Institute version. Rebuilding better, and doing so fast. (Photo and tagline: Ziv Shulman)

@CherfilsJulien @HanLi_Pasteur @FedericoPietr12 @MarieMichallet @BertolottoLab It was a pleasure to attend the defence and the workshop. Thanks for stellar organization and for the hospitality

Of course, a brilliant defense needs an outstanding jury! 💥 Huge thanks to all committee members for the terrific discussion and thoughtful questions🙏 Many thanks to @KrizhanovskyLab @HanLi_Pasteur @FedericoPietr12 #Oliver Bischof @MarieMichallet @BertolottoLab

Hard to believe it’s already been a week since Iryna’s brilliant PhD defense! 🌟 Her presentation left a lasting impression! congratulations Dr. Moskalevska on an outstanding achievement! 👏 #PhDDefense #ProudPI

WIS rocks!!!

It would be a pleasure to participate. @CherfilsJulien Thank you for the invitation

@MaxYunLab @rulandsgroup @prof_horvath @schumacherbj @dariovalenzano_ @Sofia_fe_gon @FdAdF66 Happy birthday Max!!!

What a birthday treat #ARDD2025! Thank you my dear friends @rulandsgroup @prof_horvath @schumacherbj @dariovalenzano_ @Sofia_fe_gon @FdAdF66 Vera Gorbunova, Andrei Seluanov, Peter Mullen, William Tu ❤️

@Dr_Singularity We suggested this idea 10 years ago and showed that Bcl2 family inhibitors eliminate senescent cells in the skin. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL | Nature Communications share.google/RYdUQ0vKkqNV9Y…

Breakthrough Drug Reverses Aging in Skin, Speeds Up Healing. ABT-263, a senolytic drug, accelerates wound healing in aging skin by clearing senescent cells, triggering beneficial inflammation, and enhancing gene activity.

@NatureAging @JuliaMMagdalena Thank you Hanna @NatureAging for organizing this exciting focused issue. It was a pleasure to work on it.

🎉Immune aging focus 🎉 @JuliaMMagdalena and @KrizhanovskyLab explore immune surveillance of senescent cells, including mechanisms of clearance, evasion and paracrine senescence, as well as therapeutic strategies nature.com/articles/s4358… rdcu.be/eARAC

Thank you for featuring our review

How we’re rebuilding the Weizmann Institute — and our hopes for a better future nature.com/articles/d4158…

It took me more than 10 days before I could enter Ullman and climb to the burnt lab. Heartbreaking. Thankful to @WeizmannScience for helping us get up on our feet and look forward.

@IgorUlitsky @WeizmannScience Very good point 😀

If you want an unforgettable experience, I recommend @WeizmannScience