Eduardo Marban, MD, PhD

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Eduardo Marban, MD, PhD

Eduardo Marban, MD, PhD

@MarbanLab

Dr. Eduardo Marban | Executive Director, Smidt Heart Institute @SmidtHeart @CedarsSinai Views are my own, not institutional policy!

Cedars-Sinai Medical Center Beigetreten Mayıs 2021
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
TY2 is our second #ncRNA #drug in clinical development based on the #CREDO discovery paradigm— this one is amazingly potent and effective in clearing #interstitial #debris! Work supported by @CIRMnews
JCI insight@JCI_insight

This Research Letter offers a creative approach to #sepsis based on a naturally occurring efferocytosis-enhancing RNA doi.org/10.1172/jci.in… Small noncoding RNA TY2 enhances efferocytosis and improves outcomes in a mouse model of sepsis by @AleCiulloPhD, @Marbanlab, @TheIbrahimlab & team @CedarsSinai. The image shows exposure to TY2 increases E. coli clearance by bone-marrow derived macrophages as indicated by fluorophore as a reporter of efferocytosis (green).

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Casey Davis
Casey Davis@CaseyHealthC·
@MarbanLab @joshuagoco @TheIbrahimLab I worry this TREX1 breakthrough is another we'll lose to funding chaos. Happy travels Josh. The UAE offers the stability and investment this sector desperately needs.
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
Today’s lab meeting featured @joshuagoco testing of #TREX1-enhancing #exomer TY1 on chronic #MI in mice. TY1 given 3 weeks post-MI improved function and volumes despite the chronicity of injury— does mitochondrial DNA scavenging underlie MoA? Happy travels Josh! @TheIbrahimLab
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Ahmed Ibrahim
Ahmed Ibrahim@TheIbrahimLab·
Wanted to post this article from Cedars-Sinai (penned by Kristin Reynolds) remembering my dear friend, Kiel Allen Peck and the lasting contributions he made to translational medicine and the lucky people who knew him.
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Ahmed Ibrahim
Ahmed Ibrahim@TheIbrahimLab·
Today at the @CedarsSinai @RareDiseases day, @MarbanLab and @rrogerslab elegantly outline the drug discovery potential of mining therapeutic extracellular vesicles for novel RNAs. What would later be called the "CREDO" paradigm has been @MarbanLab's vision for nearly two decades and what a privilege to see it materialize! Here's to emergent mechanisms, novel drugs, and renewed hope for rare disease patients.
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
@moorejh Congratulations Jason! I wager it’ll become a citation classic in due course. 👍👏
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
We were delighted to host Jennifer Davis of @UW at our @SmidtHeart Research Seminar. 🙏 The complex interactions between #cardiomyocytes and #fibroblasts shape myocardial function and structure; Jen’s work is at the forefront of deciphering the nature of the interactions. 👏👍
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
We discovered that cardiac cell therapy product #deramiocel ameliorates #Duchenne cardiomyopathy and, to our surprise, skeletal muscle function. Our patent, just awarded, has been validated by 4 clinical trials, including HOPE-3, in patients with advanced #DMD. @MarkAmin2019
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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
@SmidtHeart @DrAliAzizzadeh
CADECIGDL@cadecigdl

#SoloEnCADECI una conferencia liderada por expertos en la materia: Dr. Donald T. Baril, de la División de Cirugía Vascular de CEDARS Sinai Medical Center. / Dr. José A. Merino Rajme, experto Nacional en TAVR. 📍𝐇𝐎𝐘 𝟏𝟑 𝐅𝐄𝐁. 𝟏𝟔:𝟏𝟎 𝐇𝐑𝐒./ 𝐌𝐚𝐢𝐧 𝐀𝐫𝐞𝐧𝐚 La excelencia empieza antes de cruzar la válvula. #TAVI #CardiologíaIntervencionista #AccesoVascular #heartteam #cardiologia @dr.merinorajme @CedarsSinaiMed

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Eduardo Marban, MD, PhD
Eduardo Marban, MD, PhD@MarbanLab·
Devastated to learn of the untimely death of Kiel Peck, who did his 2022 PhD @CedarsSinai with @TheIbrahimLab and me. Kiel was a kind, gentle soul, supremely competent, universally loved. All of us who were fortunate to know him are devastated at the loss.
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@HopkinsMedicine @hopkinsheart @SmidtHeart @TheIbrahimLab @CIRMnews @AleCiulloPhD @kara_tsi @anhhnguyennn9