Dr Ravindhi Murphy retweetet
Strong @ChelwestFT team representation at #ESMO25 this year
Congratulations to Claire, Chloe & Kyle for their first ESMO posters
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Dr Ravindhi Murphy
728 posts
Dr Ravindhi Murphy
@ravindhi
Lower GI medical oncologist and medical adviser at Centre for Drug Discovery, Cancer Research UK.
London, England Beigetreten Eylül 2015
759 Folgt474 Follower
Dr Ravindhi Murphy retweetet
This is probably the most important publication we have published for trainees and senior oncologists alike. This provides answers to almost every question you have about surrogate endpoints in oncology. This is a must-read for anyone with an interest in cancer trials. FREE!
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Our brilliant @ChelwestFT ADOC team were delighted to be recognised by the @RMPartnersNHS rapid diagnostic clinic celebration day. The first clinic of its kind to be developed for investigating patients with vague symptoms to diagnose cancer. Earlier diagnosis improves outcomes!
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Dr Ravindhi Murphy retweetet
Metastatic colorectal cancer. Third line and beyond. How to treat and what's the evidence. Nice review in @NatRevClinOncol
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Dr Ravindhi Murphy retweetet
Attention #BCSP centres! We have created an SOP for the use of aspirin in #LynchSyndrome patients attending for #colonoscopy … please send me a message if you would like a copy - thanks! @stmarksbcsc @LynchSyndromeUK @StMarksGenomics @BowelsOfStMarks @NHSEngland
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@DrLesleyDawson2 @marklewismd @JCO_ASCO I’m doing a teaching session on adjuvant chemo for colon cancer for our resident doctors - “Trolley problem” is a great analogy!
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Every time I grapple with the "trolley problem" of adjuvant chemo in colon cancer, I return to this manuscript (written in 2016 in @JCO_ASCO & thus preceding many ctDNA-informed approaches but also foretelling the top-heavy risk/benefit of oxaliplatin)
ascopubs.org/doi/10.1200/JC…
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Dr Ravindhi Murphy retweetet
We have 2 trials of bispecific antibodies in lung cancer open and running @ChelwestFT
In fact, recruited the first patients in Europe to both of these
🦸
soria@jsoriamd
Bispecific antibodies (bsAbs) allow therapeutic applications that cannot be achieved using conventional antibodies. There are 14 bsAbs approved: 11 for cancer & 3 for non-oncology indications. This review summarizes this very active field, including bsAb signaling pathway modulators, tumor-targeted receptor agonists, ADC, bispecific T cell, natural killer cell & checkpoint inhibitors.nature.com/articles/s4157…
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Dr Ravindhi Murphy retweetet
Liver transplantation + CTx vs CTx in unresectable CRC liver metastases
🔎TransMet randomised trial
@TheLancet
doi.org/10.1016/S0140-…
👉5-yr OS: 56.6 vs 12.6%
👉Recurrence after LTx: 72%
🧐Impressive study, impressive results
❗️LTx valid option in highly selected pts
@myESMO @EASLedu @ILCAnews #livertwitter
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Great to share our data & generate discussion around management of malignant bowel obstruction @myESMO . Data collected from the @WestMidHospital @ChelwestFT AOS team highlighting need for MDT involvement and national guidelines to improve patient care and experience #ESMO2024
Tom Newsom-Davis@tnewsomdavis
Malignant bowel obstruction: from outstanding @WestMidHospital AOS team ❗️24% died during admission ❗️74% had no further SACT ❗️Only 50% referred to palliative care 👉 Need MDT discussion for every case 👉 Need national guidelines for best management #ESMO2024
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@Leeshcons @samwarb @peterc1982mfc @oasis I haven’t received my confirmation but to be fair I only did it 20 mins ago and I guess a lot of people will be doing it this morning! Here we go again…
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@tnewsomdavis These are hilarious! I hope they do this at ESMO also
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So this is genius: make your own ribbons
And the fluorescent yellow ones clearly the best
Always fun to tease the conference ribbon exhibitionists
#WCLC24
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@DrEmmaHolliday @MDAndersonNews This is a great thread - very fun way of thinking about the way treatment is evolving!
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I was tasked with teaching @MDAndersonNews residents & med students about #rectalcancer.
The field has changed a lot since I started in 2012. You could say… there have been many “eras” of hot topics in the field of RT for rectal cancer!
(I had too much fun with this…)
GIF
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Great to join @Cancer52org at the #bigcancer52conversation today, talking about the DETERMINE clinical trial which is open for patients of all ages with rare cancer across the ECMC network @CR_UK @ECMC_UK
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Dr Ravindhi Murphy retweetet
With the rising incidence of #colorectal #cancer (particularly in younger adults) this really is a ‘tidal wave’ of a response curve - can’t wait for the phase 3 RCT!
@kevinjmonahan @bowelcanceruk @bhmullish @PaulKMiddleton @ravindhi
Myriam Chalabi@MyriamChalabi
Ecstatic and proud to share the NICHE-2 results, now published in @NEJM. Out of 111 pts, 95% had an MPR , and 68% a pCR after only 4 weeks of #neoadjuvant #immunotherapy. Grateful to the pts and colleagues who made this possible. @HaanenJohn nej.md/3Ku4X0H
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I am beyond proud to have got a GOYIA by @ConquerCancerFd to support our research on HIV-associated HCC. This would have never been possible without the support of my team and my inspiring PI @DJPinato at @imperialcollege ! Looking forward to generating new data for our patients!
Conquer Cancer, the ASCO Foundation@ConquerCancerFd
Congratulations to this year's class of Conquer Cancer Grant and Award recipients! We can't wait to celebrate with you at #ASCO24! Full list of recipients: brnw.ch/21wKdIf
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Joe's story themulberrycentre.enthuse.com/pf/joe-nunan After emergency surgery and 18 cycles of chemotherapy, Joe is running to raise money for @MulberryCentre on his chemo break. What an incredible person living with bowel cancer and such a worthy cause to support. Please consider donating!
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Strong @BTOGORG presence on fun run
Joined by wonderful palliative care colleague Ruth Caulkin
Excellent effort by all 👏
And it didn’t rain!
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Nice to see some of our @ChelwestFT ADOC data being shared at #BTOG24. Our RDC has a brilliant team of GPs, nurses and consultants to improve faster diagnosis of cancer in patients with complex and vague symptoms
Tom Newsom-Davis@tnewsomdavis
Proud to see @ChelwestFT Rapid Diagnostic Clinic data presented at #BTOG24 👉 Lung is commonest cancer diagnosed 👉 RDC presentation associated with older age, complex symptoms & raised inflammatory markers 👉 RDCs import patent in presentation of lung cancer #LCSM #BTOG24
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Dr Ravindhi Murphy retweetet
A smokefree future could mean tens of thousands fewer cancer deaths each year in the UK.
Read more about why today's tobacco Age of Sale legislation is important, including thoughts from our Executive Director @IanWalker_CRUK 👇 bit.ly/44h9eOl
#SmokefreeUK
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Delighted to head to Westminster today to support @Cancer52org manifesto for rare cancers. We are passionate about supporting patients with rare cancers and improving outcomes. We hope many of them will be involved with the DETERMINE trial running across the UK @ECMC_UK @CR_UK
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