@jillfeldman4 Same thing with palliative care, which is supposed to be offered to Stage IV cancer patients but rarely is. Very frustrating.
English
AnneL
33 posts
We have to stop describing and start actionizing!
But... how do we FIX it?!
Dr. Amy C. Moore@acmoorephd
Only 36% of patients with #NSCLC in the US get appropriate personalized care. I was on a call earlier this week where we acknowleged that this disgraceful statistic is even worse in other parts of the world. How do work to ensure equitable access to optimal care for all?
English
@CANsurvive So good that you are feeling more at peace and enjoying hat dances with your best guy!
English
@CANsurvive This is beyond difficult in so many ways. Wishing you peace of mind and a soothed soul.
English
@Martha__Carlson @the_rightdose @JaniceTNBCmets @itsnot_pink @swaggsheila1 @CANsurvive @maryam_lustberg Thank you Stacey! Waiting to hear back from them.
English
Thanks for letting @the_rightdose know Stacey! Tagging @JaniceTNBCmets @itsnot_pink @swaggsheila1 @CANsurvive @maryam_lustberg #TheRightDose #cancer
Stacey Tinianov (she/her) MPH, BCPA@coffeemommy
FYI - @Martha__Carlson, thinking you and Anne should connect with @JasonSicklick & @Dr_R_Kurzrock about the @the_rightdose initiative (if you haven't already). She is singing the Right Dose song on stage at #PMWC23
English
@dradityabardia @OncoAlert Dr. Bardia, congratulations on playing such a key role on this drug's success!
English
FDA approves elacestrant, oral SERD, for ESR1-mutated ER+ metastatic breast cancer, based on phase 3 EMERALD clinical trial. Last endocrine therapy approved was ~ 20 years ago. #bcsm @OncoAlert Link to article and label: accessdata.fda.gov/drugsatfda_doc… ascopubs.org/doi/pdf/10.120…
English
@CANsurvive Flori, of course you're upset and scared. Anyone would be. But they are able to perform endoscopic surgeries that would have been unheard of even a decade ago. Sending love.
English
@CANsurvive This must be so frustrating and uncomfortable. A weird thought: might you ask your Dr. if you can dissolve the tablets in a little water and drink it?
English
@CANsurvive So sorry this happened and relieved it's behind you. Perhaps soft foods for a day or so just to recover. Sending hugs!
English
English
Congratulations to @maryam_lustberg! Dr. Lustberg was named to the third annual @cancerhealthmag 25 list, celebrating individuals who do extraordinary work to improve the lives of people with #cancer. #bcsm bit.ly/3mOu4zk @SmilowCancer @YaleMed @YNHH
English
@al_in_sweden @LGM_Biostats @davidcnorrismd @ErikaHamilton9 @drsarahsam If the lower dose is well-tolerated and effective, why titrate up?
English
@LGM_Biostats @davidcnorrismd @ErikaHamilton9 @drsarahsam @AnnePCDI Hi Liz…nice to make your acquaintance. I agree, as pharma/regulator, we should aim to determine the right starting dose, and then how/when to titrate up. Generally starting high just generates more severe toxicities that could have avoiding with a “smart” titration algorithm.
English
📣 dose reductions do not impact outcome with ribociclib in MONALEESA2 📣
📌2/3 patients on the study actually had dose reductions
🎯83% of pts feel better after reduction
#ASCO22 #bcsm #ASCO22 @drsarahsam
Chicago, IL 🇺🇸 English
@itsnot_pink There's a subconscious tendency to perceive "newer is better."
It ain't necessarily so.
English
Re: TROPICS-02
It would be very different is saci was much easier to tolerate than chemo. But that’s not the case. If ADCs are smart bombs, this one is “very bomb & little smart”.
With that in mind, the difference of only 1.5 months in PFS is even less meaningful.
#ASCO22
English
@stage4kelly @hoperugo @UCSFOrthosurg Hoping all goes well for your husband, and that the surgeries make him stronger and enable him to feel better!
English
So bummed I’m missing #ASCO22 but incredibly grateful to Dr @hoperugo for facilitating getting my husband to @UCSFOrthosurg - he was admitted straight from clinic today and will be having the 1st of a series of surgeries tomorrow. Good juju welcome!
English
@davidcnorrismd @al_in_sweden @jillfeldman4 @NicoleKuderer @LGM_Biostats @FDAOncology We need data about the efficacy of lower doses compared to the RSD. It's perfectly logical for a pt to ask,"If I take a lower dose, I'll probably feel better, but what about my survival?"
English
@coffeemommy @jillfeldman4 @maryam_lustberg @crisbergerot Stacey, congratulations to you and the team!
English
@jillfeldman4 @maryam_lustberg ❤️ This team was amazing. As you know "validation of feelings" is my heartsong w/ regard to 1st step in psychosocial support. I didn't attempt to petition for "being seen, heard & held" but they likely would have allowed it (& I feel like it comes across just fine) @crisbergerot
English
So happy to see this important topic on fear of recurrence or progression addressed.
Early recognition, validation of feelings and some ways to support patients and their families - must read!
Thank you @coffeemommy @maryam_lustberg & all who contributed!
ascopubs.org/doi/full/10.12…
English
@al_in_sweden Interesting concept indeed. Wondering what criteria you would envision being used by the titration algorithm?
English
@AnnePCDI I would go even further. Imagine in the FDA had a webpage with a recommended dose titration algorithm (starting dose, and when to titrate up/down). Better still where patients, with their consent, could even upload their dose ‘trajectory’ and outcomes, to share/learn with others.
English
Watching #ProjectOptimus online. Will we hear anyone say that we need different dose regimens for different patients? Everyone says "we have heterogeneous patients & heterogeneous outcomes", but no one seems to want to explain the consequence of that...we need to dose titrate!!
English
@al_in_sweden A range of doses is something I've always hoped for! Just Imagine if the package insert depicted a range of doses from which the best dose for a particular pt could be selected...
English
@AnnePCDI Hi Anne…great to know someone read my comments at the meeting! Yes, no need to titrate up if drug working well. However having a very wide range to titrate over will allow each patient to find their dose. E.g. currently low/high might be 10/20mg. I am talking about,say, 1-50mg..
English