Zbynek Kozmik

Happy to share that our article "Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head" has just been published in Nature Communications rdcu.be/dWVEN We show #neuralcrest-like and prechordal plate-like cells in amphioxus!

@JanMasekLab ...and the last member, Lucka, generated animal images for the summary Fig.7...

@KozmikLab Big congratulations to the whole research family :D!

1/n Based on single-cell transcriptomics, signaling pathway manipulations, and cis-regulatory analysis we propose that some key innovations in vertebrate head development, such as the prechordal plate (PrCP) and neural crest (NC), can be traced back within the chordate lineage.

@PavelTomancak rdcu.be/dWVEN I was stupid enough to think it would get linked to the original tweet. Too late to ressurect it.

@KozmikLab Link Zbyňek, you forgot the link to the paper 😂 Congratulations

7/n If you want to listen to AI-generated podcast that explains our paper in plain English: notebooklm.google.com/notebook/5a2bf… Just a comment on what AI got wrong: we have not shown actual NC-like cell migration (but we are working on it…)

6/n Congratulations to Iryna for designing the study, performing numerous experiments, analyzing the scRNA-seq data, guiding the students involved, and ultimately bringing the entire project to completion!

From Fish to Mammals: Unraveling Brachyury Control in the Notochord by @aburger2009 & @KozmikLab, w/@EKFarley @MaxYunLab @AxelVisel @m_osterwalder @LiciaSelleri @FishEvoDevoGeno & teams is now out in nature.com/articles/s4146… Wonderful collaboration. Happy to be part of it!

Congrats to a former PhD student of @KozmikLab and alumnus of @imgprague Peter Fabian for receiving the prestigious #ERCStG. Well deserved! You are such a great person. Smart recruitment by @MUNI_Science and great boost for Czech DevBio community. Go Peto, go... @Fabian_Lab

Extraordinary claims require extraordinary evidence. In our new @Nature paper, Darrin Schultz @conchoecia used the position of genes on chromosomes to show that ctenophores (comb jellies) not sponges are the sister-group to all other animals. nature.com/articles/s4158…

For 100s of years, sponges were assumed to have split first. In 2008 a transcriptome-based study led by @caseywdunn suggested ctenophores were sister to other Metazoa. The debate has bounced back and forth, ever since, even with more genomes sequenced.

If you don't get it, you don't get it Download our (updated) massive database of POSTDOC fellowships. We list 373 fellowships w/ description, $ amount, deadline, and eligibility criteria (e.g. citizenship). HERE: research.jhu.edu/rdt/funding-op…

I am so proud! Big congratulations to a former PhD student of @KozmikLab and alumnus of @imgprague Peter Fabian.

Seeing humans through an evolutionary lens science.org/doi/10.1126/sc…

Hooray, it’s #FluorescenceFriday! And we are admiring the beautiful work of Cassie Kemmler, @chrmosimann @aburger2009 @blockintheback @kwantourage & colleagues. They share their next-generation plasmids for transgenesis in zebrafish and more! @Dev_journal: journals.biologists.com/dev/article/15…

Happy to share our TOGA manuscript, now out in Science. Project started 6 years ago, we and others already used TOGA in numerous projects. TOGA integrates gene annotation and orthology inference, and scales to hundreds of genomes. science.org/doi/10.1126/sc…