new299

@sichuan_mala Their investor also did a Nazi salute in an interview discussing the company: bitsof.bio/p/nucleus-geno…

I've just written a new post raising a series of concerns about Nucleus Genomics, a company that offers embryo selection services based on polygenic scores for couples undergoing IVF. I was shocked by the degree to which Nucleus's work is obviously plagiarized or simply wrong.

@mehtamanal @CatharineAquino @GenomicsCow @OmicsOmicsBlog @CarlosEAlvare17 @BioMath @ElemBio @MollyminHe @FTC There flowcells won’t work without RFID (or the illumina provided bypass code). Maybe possible to reverse engineer this to create compatible flowcells etc.

@CatharineAquino @GenomicsCow @OmicsOmicsBlog @CarlosEAlvare17 @BioMath @new299 @ElemBio @MollyminHe @FTC Does Illumina use RFID to block their sequencers from operating normally when using non Illumina flowcells? Does it void the warranty on instruments? If the answer to either of those questions is yes, the FTC's right to repair ruling could be meaningful.

Any implications for genomics service providers?🧐 The US government has granted copyright exemption giving restaurants the right to repair broken ice cream machines by others besides the manufacturer.🍦😅 @BioMath, @GenomicsCow, @OmicsOmicsBlog?

@will_whang Looks wonderful! Where do you buy the sensors? I can never find the bare parts!

I can finally, finally able to drive IMX585 VSYNC and HSYNC! After this bring up I can finally start designing my all-in-one camera hat.

@will_whang @Raspberry_Pi Hey Will, weird question. But do you know what markings are present on the IMX283 sensor die? I'm trying to identify a camera module...

Introducing the project: IMX283 1" CMOS for @Raspberry_Pi This should be the largest CMOS that can connect to RPI directly (CSI-2).

Yet another exciting project

@mehtamanal @Lightcast_bio @OmicsOmicsBlog @AlbertVilella @alexgdickinson Wrote about them a while back here: aseq.substack.com/p/lightcast-di…

Yet another well funded droplet based single cell sequencing company. Meet @Lightcast_bio genomeweb.com/advances-singl… $TXG $ILMN @OmicsOmicsBlog @AlbertVilella @new299 @alexgdickinson

@mehtamanal @coregenomics nope! could be worth a look!

Do you know much about them, @coregenomics? @new299

Some more info on the substack: aseq.substack.com/p/pacbios-sens…

Sequel I and IIe chip layouts.

@gaygirlinalep ASeq founded by @new299 - sequencing geeks (about 2/3 anonymous profiles) discussing sequencing tech discord.gg/hR2fbpct

A final reminder of my COI: I am long established consultant for Oxford Nanopore (before the first release) and I am shareholder. No company vets my social media :)

@mikelectricstuf Sounds similar to this: everydaything.substack.com/p/a-mode-scram…

What kind of witchcraft is this? This optical fibre carries a 532nm laser beam to the head of a biotech dna thingy. Half way along there's this vibration motor that jiggles the fibre up & down a bit. What the.....?

I created a new substack with the intent of connecting seed stage startups to early stage investors. Info here: aseq.substack.com/p/connecting-b…

I’ve just discovered that being able to not have me comment on opinion pieces is worth $66.88 Anybody else want to buy me off? I accept Venmo. Rates are negotiable

Put some dye on a MiSeq to see if I can use it as a epi fluorescence microscope. Seems to work ok! aseq.substack.com/p/some-atto-53…

Ultima Unpatterned (not) flowcells. aseq.substack.com/p/ultima-unpat…

@TechnicalVault @OmicsOmicsBlog @mehtamanal @coregenomics @pepetideo @rravi @AlbertVilella @SanDiegOmics @HesaamE @BioMickWatson @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC They are using the IP in this case.

@OmicsOmicsBlog @mehtamanal @new299 @coregenomics @pepetideo @rravi @AlbertVilella @SanDiegOmics @HesaamE @BioMickWatson @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC Biggest difference is whether the patent is essential for the field and there is a reasonable offer to license it. Patents are to promote the progress of the arts not to stall them. Buying up IP that you don't use to trip up your competition... that's prima facie antitrust.

Omniome raises $60 million Series C bringing total funding to $145 million!! What's the play for these short read sequencing companies? With $ILMN patents expiring, won't there be massive price compression for short reads? @SanDiegOmics @coregenomics prnewswire.com/news-releases/…

@mehtamanal @OmicsOmicsBlog @coregenomics @pepetideo @rravi @AlbertVilella @SanDiegOmics @HesaamE @BioMickWatson @TechnicalVault @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC These patents all just seem pretty broad… you could argue in favor of this: gives investors more of an incentive to invest. Or against: gives a company too strong a monopoly.

@mehtamanal @OmicsOmicsBlog @coregenomics @pepetideo @rravi @AlbertVilella @SanDiegOmics @HesaamE @BioMickWatson @TechnicalVault @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC I’m not sure I would solely say it’s about outspending in 10Xs or Illumina’s cases. 2-color patent was enforced against Illumina for example, so not always clearly in their favor..

@mehtamanal @coregenomics @pepetideo @rravi @AlbertVilella @OmicsOmicsBlog @SanDiegOmics @HesaamE @BioMickWatson @TechnicalVault @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC I wonder if the total market size is big enough to get them interested?

@coregenomics @pepetideo @rravi @AlbertVilella @OmicsOmicsBlog @SanDiegOmics @HesaamE @BioMickWatson @TechnicalVault @PerkinElmer @aboutKP @NgsRob @nanopore @ZymoResearch @RadeDrmanac @CompleteGenomic @Varro_Analytics @KerrisdaleCap @CitronResearch @FTC @illumina @slavov_n @linakhanFTC This is exactly why $TXG should be in @linakhanFTC’s crosshairs. They are stifling innovation. $OMIC $NSTG 🙏 @new299 aseq.substack.com/p/singular-spa…

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