Astro Master Grower

JUST IN: Anthropic is now projected to hit a $2,000,000,000,000+ valuation this year.

"A simple way to put this is: How many ideas does one person have in a day, and how many of those things do they actually get to do? Until that proportion is 100%, you know there is a pretty meaningful bottleneck in terms of the drudgery of execution. I don’t think it’s anywhere close to 100%—it’s probably like 5%. You have all sorts of different ideas of things you’d want to do or build or try, and in practice it’s much harder to actually do them. I think of that as one of the big things AI will unlock. You see this especially in software. I have never met an engineering team that thought about their work as, alright, we’re shipping this project this month, and then next month we’re all done, no more software, we’ve built everything we wanted to build. It’s always the opposite—you have 85 projects and you have to pick six because that’s how much bandwidth you have. What we’ll get to see is that so many more people will just get to do all of the things they want to go do. When people say they love building software, what is it that they love? In reality, there’s this 10% of the job which is really just getting to express yourself—thinking about the trade-offs you want to make for every problem, what architectures you want to use, what the specific product is you want to build. And then there’s this other 90%, which is code monkeying and execution. When people say they really love building software, it’s usually the former that they gravitate towards. It’s the same in every field, and we’ll get to a point where you can just do 10 times more of the 10% you actually love."

ok actually insane paper published yesterday a research group in Korea built a gene switch you can control wirelessly using electromagnetic fields they exposed mice to 60 hz EMF (same frequency as your wall outlet) using a pair of large coils that generate a uniform magnetic field around the animal, for cyclic 3-day on / 4-day off pulses they showed this could: - activate OSK to do epigenetic reprogramming in progeroid and aged mice, extending lifespan and reversing aging markers across multiple tissues - conditionally switch on mutant amyloid genes only in aged mouse brains, letting them separate aging effects from amyloid effects to study AD biology in a way previous models couldn't no drugs, no impacts, just a magnetic field from outside the body

Thinking, as with any other hobby, is best done in moderation.

This morning, I asked President Trump if he’s okay with the Iranians charging a toll for all ships that go through the Strait of Hormuz, he told me there may be a Joint US-Iran venture to charge tolls: “We’re thinking of doing it as a joint venture. It’s a way of securing it — also securing it from lots of other people.” “It’s a beautiful thing”

Custom orders of the Tesla Model S & X have come to an end. All that’s left are some in inventory. We will have an official ceremony to mark the ending of an era. I love those cars. This was me at production launch 14 years ago: