Rossjohn lab

In collaboration with labs @PN0rmski @KatherineKedz @AndrewB34372462 @syctong and co-authors, paper published @MonashUni: An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania: Cell cell.com/cell/fulltext/…

🚨🧬An in vivo cell therapy engineering platform of transformative potential. Congratulations to @j_eyquem and team on a breathtaking (and groundbreaking) body of work. @parkerici @UCSF nature.com/articles/s4158…

NHMRC Investigator Grants out today. A devastating day for many. I have already received messages from some of the best researchers I know who have missed out. The senior levels had a cutoff of 5.93 (females), 6.2 (males) - according to my sources. The impact will be wide spread. The damage being done at the moment to the sector is totally unacceptable. We need to do a lot more to support our research community.

#StarsOfScience – Professor Jane Visvader's groundbreaking discoveries at @WEHI_research have fundamentally changed how we understand breast development and cancer.

Congrats to PhD student, Liam Rashleigh, whose 1st authored paper on gd T cell receptor recognition was published today @Structure_CP cell.com/structure/full… #GDTcellclub @MonashUni @RossjohnLab

Early bird registration pricing for CD1-MR1 2025 ends this Friday, 6th June! Get on it 👉👉 cd1mr1.com

Congrats to Hien, 1st author of this study that arose from her hard work during her PhD.

In collaboration with Moody lab, latest paper from @RossjohnLab describing the structure of a lipopeptide bound to a MHC-I like molecule found in chickens - hopefully this study will not ruffle too many feathers.

Your immune system gradually loses it top team players when we get older 👱➡️👵 Our study in @eBioMedicine investigates how long our good immune cells stay around – a 🧵⬇️ go.unimelb.edu.au/4sep @CvandeSandt @KatherineKedz @TheDohertyInst #Influenza #AgingResearch

Our latest paper demonstrating the potential of “our” DOT cells against colorectal cancer has just been published in @NatureCancer: rdcu.be/ehYwG Many congrats to the whole team, especially @RafaelBlancoDom! :)

Recent paper from lab describing a peptide-independent MHC-restricted T cell receptor nature.com/articles/s4146… in collaboration with La Gruta lab @MonashUni @Monash_FMNHS @RossjohnLab @NatureComms

In collaboration with @NicoleLaGruta1 and colleagues, latest paper from @Jamie_Rossjohn lab describing role of Lck-coreceptor assocation in T cell function. @MonashUni science.org/doi/10.1126/sc…

Researchers in Science #Immunology have identified CD8+ T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. @Jamie_Rossjohn @kedzierskalab scim.ag/4hpSzh1

🚨 Flu breakthrough! 🚨 Researchers at @TheDohertyInst & @MonashUni have discovered immune cells that recognise flu viruses even as they mutate—a further step toward a universal flu vaccine. go.unimelb.edu.au/d7z8 @UniMelbMDHS @TheRMH @oanheei @Jamie_Rossjohn @kedzierskalab @KatherineKedz

Our latest study @SciImmunology identifies the molecular determinants of cross-reactive B35/NP418-restricted CD8+ T cells across IAVs from 1918 H1N1 to 2024 H5N1, and assesses their functionality. @KatherineKedz @RossjohnLab science.org/doi/10.1126/sc…

TCR-peptide-HLA ternary structures define molecular mechanisms of TCR cross-reactivity toward natural influenza variants @SciImmunology science.org/doi/10.1126/sc… @RossjohnLab @Jamie_Rossjohn @kedzierskalab @KatherineKedz

science.org/doi/10.1126/sc… First paper from the @JohnstoneLab for the year and a brilliant collaboration with @TheDohertyInst colleagues Dan Utzschneider and Alex Kallies. Thanks to all @PeterMacRes @PeterMacCC for help and support and great job Dane Newman and Leonie Cluse!

Ziggy enjoying park time #roughcollie

Researchers paid $8.968 billion for their findings to be freely accessible. 🧵1/10

Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs doi.org/10.1084/jem.20… @MonashBDI @nhmrc @WaelAwadMoh @MonashUni @Jamie_Rossjohn @JExpMed