Chao Wu 伍超

this is actually insane > be tech guy in australia > adopt cancer riddled rescue dog, months to live > not_going_to_give_you_up.mp4 > pay $3,000 to sequence her tumor DNA > feed it to ChatGPT and AlphaFold > zero background in biology > identify mutated proteins, match them to drug targets > design a custom mRNA cancer vaccine from scratch > genomics professor is “gobsmacked” that some puppy lover did this on his own > need ethics approval to administer it > red tape takes longer than designing the vaccine > 3 months, finally approved > drive 10 hours to get rosie her first injection > tumor halves > coat gets glossy again > dog is alive and happy > professor: “if we can do this for a dog, why aren’t we rolling this out to humans?” one man with a chatbot, and $3,000 just outperformed the entire pharmaceutical discovery pipeline. we are going to cure so many diseases. I dont think people realize how good things are going to get

We built a browser with GPT-5.2 in Cursor. It ran uninterrupted for one week. It's 3M+ lines of code across thousands of files. The rendering engine is from-scratch in Rust with HTML parsing, CSS cascade, layout, text shaping, paint, and a custom JS VM. It *kind of* works! It still has issues and is of course very far from Webkit/Chromium parity, but we were astonished that simple websites render quickly and largely correctly.

Trump announces an "unprecedented four-day athletic event" with "one young man and one young woman from each state and territory"

BREAKING: Databricks is raising over $4 billion in Series L funding at a $134 billion valuation.

One of my favorite lessons I’ve learnt from working with smart people: Action produces information. If you’re unsure of what to do, just do anything, even if it’s the wrong thing. This will give you information about what you should actually be doing. Sounds simple on the surface - the hard part is making it part of your every day working process.

Prediction markets are betting on Gemini 3 release next week $goog

UCSD’s “Math 2” course teaches grade-school math (grades 1–8) to freshmen. From page 49 of the university’s own report: • 25% of students got 7 + 2 = ___ + 6 wrong • 61% of students, a large majority, couldn’t round 374,518 to the nearest hundred • 37% of students couldn't subtract fractions UCSD is ranked as the nation's 5th best public university. Universities are cooked.

OMG tinted looks so much better I am switching to Tinted

Ok this tweet about upcoming changes to ChatGPT blew up on the erotica point much more than I thought it was going to! It was meant to be just one example of us allowing more user freedom for adults. Here is an effort to better communicate it: As we have said earlier, we are making a decision to prioritize safety over privacy and freedom for teenagers. And we are not loosening any policies related to mental health. This is a new and powerful technology, and we believe minors need significant protection. We also care very much about the principle of treating adult users like adults. As AI becomes more important in people's lives, allowing a lot of freedom for people to use AI in the ways that they want is an important part of our mission. It doesn't apply across the board of course: for example, we will still not allow things that cause harm to others, and we will treat users who are having mental health crises very different from users who are not. Without being paternalistic we will attempt to help users achieve their long-term goals. But we are not the elected moral police of the world. In the same way that society differentiates other appropriate boundaries (R-rated movies, for example) we want to do a similar thing here.