@AlexanderKalian Weather is pretty complex and AI models solved that (don’t need precise physics models anymore).
Sure AI will be an approximation, but it will eventually become accurate enough to be extremely useful.
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Alex Simpson
897 posts
Alex Simpson
@AlexSimpson_96
Building startups with @yongjiean. prev: AI research at Tsinghua University.
London, England 参加日 Ekim 2016
817 フォロー中993 フォロワー
Every time I tell AI utopianists that biology is too complex for AI to "solve", they cite the success of AlphaFold.
No, AlphaFold did not "solve" protein folding. It gets broad structures correct ~70-88% of the time (depending on evaluation), enabling useful but flawed statistical guesses.
True "solving" would require ~99.9%+ accuracy, practically zero meaningful edge cases, and high confidence across fine details like side chains and conformations.
Even then, this is just one narrow slice of the complexities of proteomics.
The persistent gap between the "AlphaFold solved protein folding" claim and reality is a perfect example of AI overhype in biology.
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@0xSero I get computer use to dump stuff into 5.4Pro if it’s needed, wait for result, then continue in codex once it’s done.
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@rahikazzz @ajlamesa There are some niche places in Shanghai with tap water, but it is a valid criticism that it’s rare. My expensive apartment in Shanghai never had it, but even the poorest parts of UK have it.
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@ajlamesa The tap water in my building is perfectly drinkable, dipshit.
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You can’t even drink the tap water in Shanghai.
Jostein Hauge@haugejostein
I agree. Shanghai is the most developed megacity I’ve seen — more so than New York, Tokyo, or London. I might have to reconsider if I visit Shenzhen or Hangzhou.
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@rand_longevity Human trials and regulation are a huge bottleneck. If we solve that (AI simulated testing, artificial organs for testing etc), then sure, it could be a few years. But if not, it will be 10+ years.
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@l_mejiaC It’s been v useful for me. Probably depends on the use case.
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Unpopular POV computer use in codex is SOTA and still not really useful. It keeps making mistakes with clicks, a lot. I mean it is the best, but not really useful in my use case. I hope this is fixed once spud and super app arrives next thursday (this is an especulation).
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@gdb Probably had the most productive day of my life so far. Computer use is magic.
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@meadwaj I built an app. After years of earning 0, it is finally profitable. I’ve started hiring TikTok creators to grow more. Each video earns $10 revenue, so I can pay them at most $9 per video. With this rule I need to pay $1000+ per video. Clearly I’ll have to hire abroad instead.
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Of course they do. It's a good idea.
Politics UK@PolitlcsUK
🚨 NEW: 65% of Brits support the Green Party's policy of capping CEO pay at ten times the pay of the lowest paid employee
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@pacer142 @aswren I built an app. After years of earning 0, I finally make good profit. I hire TikTok creators to grow faster. Each video adds $10 in revenue, so I pay them $9. With this law, I must pay them $1000+ per video. Clearly, I will have to stop TikTok marketing (or hire outside Uk).
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@aswren If you speak about people who might be your minimum wage employees as "losers", I'd say that alone speaks volumes about your attitude to others.
1:10 may not be practical, but I'd struggle to say 1:20 wasn't. Footballer salaries for instance are obscene.
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@piri_io_ I built an app, worked 7days/week for years and now it makes good money. I hire TikTok creators. I earn $10/video, so I pay the creators $9. That leaves $1 for me, making it worth the effort of hiring/training them. With new law, I must pay $1000+ per video. So, I won’t hire.
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@Himmura @patrickbetdavid China has been capitalist since 邓小平. The last time they were truly communist was under Mao, and they had extreme famine.
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@patrickbetdavid Da fk man. Russia and China are doing pretty well. That aside there’s a difference betw communism and democratic socialism..stop pretending it’s the same…that’s lying. Or educate yourself if ure really that ignorant.
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Communism has a 100% track record of failure.
It loses its best people.
NY City better brace for impact.
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@LaurieGreen36 With 1 billion AGI scientists working on it, it’s plausible it can be solved in a few years. Just need to find some solution to human trials bottleneck (digital simulated biology, artificial organs for testing, sth like this).
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A lot of people say they begin to no longer recognise themselves in their 40's. When will we cure this?
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@sp4rkl3jumpr0p3 It’s important to be paid proportional the value you produce. A brain surgeon that trains for years and does super stressful work needs more pay than a cleaner who works 1 day/week, otherwise they would choose to be a cleaner too. If the fair value is 100x salary, so be it.
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Outrage at a CEO only getting £120k a year and not outrage at the cleaner only getting £12k a year is why the country is in such a mess
IC@isaac1k__
didn’t even read the rest, 10:1 pay ratio is the dumbest thing i’ve ever heard in my entire life. you could be a CEO, a cooperate lawyer, a top level surgeon, but you can’t earn over 120k because the part time cleaner earns 12k.
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@TraceyRyniec @btide72 @AJManaseer Tbf I agree with that. It’s been tried many times and never worked, but it was in his campaign so he should at least try it again one more time. It’s what the voters wanted, so it’s his job to do that, regardless of history/evidence.
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@btide72 @AJManaseer We'll see. Doomers got to doom. At least he's trying to fulfill his campaign promises.
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“May the most affordable grocery store win” he says, after we learn that his store will not pay rent or property taxes. Well what sort of prices could a corporate store offer with two of their biggest cost inputs slashed to $0?
I look forward to observing how this train wreck progresses. My hunch is that it will become A) shoplifted ruthlessly, B) staffed by socialists who will go on strike annually for above market pay and “better working conditions”, and C) still lose money despite not paying rent or property taxes.
Novara Media@novaramedia
New York City mayor Zohran Mamdani has announced the location of the city’s first publicly owned supermarket, marking a step towards delivering on his pledge to bring down the cost of food. The city will spend $30m (£22.3m) on the store, which is due to open next year at a marketplace in East Harlem, Mamdani announced on Sunday during an address to mark his first 100 days in office. He wants to open five of the stores - one for each of the city’s boroughs - before the end of his first term in 2029. They will operate without paying rent or taxes and pass those savings onto shoppers. During his address, Mamdani rebutted neoliberal arguments about the effectiveness of publicly owned businesses. "Some will insist that city-owned businesses do not work, that government cannot keep up with corporations," he said. "My answer to them is simple: I look forward to the competition. May the most affordable grocery store win." Mamdani has been quick to deliver on several of his major campaign pledges – many of them aimed at bringing down the cost of living – since taking office on 1 January. He announced the introduction of a free childcare scheme, intervened on behalf of tenants living in poor conditions and secured millions of dollars of restitution for workers. Former presidential candidate Bernie Sanders made a surprise appearance at Mamdani’s address. "I know that the mayor has been criticised and some say this is a radical idea," he told the crowd. "I'll tell you what is a radical idea: Giving tax breaks to billionaires. Throwing people off health care. That's radical. What's radical is starting a terrible war. That's radical. But providing affordable food to working families? That's not radical, it's exactly the right thing to do."
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@BallouxFrancois It’s clearly on a completely different tier to actually safe cities like Singapore. It’s mostly fine during day (except for phone theft), but it could be a lot better. We should have higher standards.
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I live in London, and I'm well travelled. London is one of the safest places I've ever been to. It is a beautiful, diverse and vibrant city and there's no 'no go' zone, absolutely none. Every bit of London, be it posh or poor, is remarkably safe by international standards.
LBC@LBC
'Sadiq Khan is worried people can see what's really going on.' Reform UK’s London mayoral candidate @policylaila discusses the Met Police's dismissal of a rape case as she outlines her concerns about rising crime issues in the capital.
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@PositivFuturist @iamstilicho Mass migration could be existential though. Within 4 years we could completely lose democratic voting power to freshly imported migrants. At that point the country is unrecoverable.
Bad economics can always be fixed though.
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@iamstilicho You don't know that for sure..
I think at the actual levers of power and with the media to appease they wouldn't be much different
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Since I have my TikTok slideshow automation set up, I decided to take a look at apps that could be successfully marketed using only slideshows.
By “successfully,” I mean my criteria was for the apps to be no older than 1–1.5 years and not have less than $5k (or 5k downloads) on Sensor Tower.
So I spent a couple of days browsing TikTok manually and also using my TikTok research agent, and honestly, I got a bit disappointed.
There are TikTok accounts with viral posts (millions of views) and even the app name in the description, but Sensor Tower still shows less than $5k for them. I didn’t take older apps into account because I was specifically looking for new projects that recently went viral and became profitable.
The only niche I’m 100% confident about is study apps. I might need to look at it from a different angle though and there might be some other areas that work for slideshows
If I don’t find anything convincing, then I’ll probably have to step into the AI UGC content world, which is another learning curve but could be the right choice, who knows 🙂
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@MicrosoftvApple @English_Jew @haugejostein Indian culture is important. Pakistani culture is important. Japanese culture is important. British culture is important. Culture adds richness to life, and we should try to preserve it, not erase it.
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@English_Jew @haugejostein I didn't answer my own question because people who migrate to Britain do it for opportunities. I don't think the same will apply between India and Pakistan
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Says someone whose nation literally looted trillions from India during colonial rule.
Severus@SeverusChud
There's something really tragic about watching old footage of England and realising your entire civilisation has been stolen from you.
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The strongest case against me is that I've built an identity around not dying so completely that I can no longer evaluate evidence that dying might be acceptable. If survival is the only framework, I have no way to test whether survival is worth it.
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