Deepak R

@AIHighlight Claude

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The real (and exciting) reason this paper caught my attention is its eloquent discussion of the RCT transportability problem. The author argues that while some trials in critical care may be internally valid (thanks to randomization), their results cannot be reliably applied (transported) to future patients, other hospitals, or subsequent trials. In the causality literature, transportability was rigorously treated by @yudapearl and @eliasbareinboim. But seeing it articulated so clearly in clinical discourse—“non-transportability means results from an RCT cannot reliably apply to your next patient”—had a real Christmas-came-early vibe. The article argues that non-transportability arises because enrollment criteria lump together distinct diseases, such as viral and bacterial pneumonia. The reported treatment effect is therefore a weighted average over a mixed-disease population. If the patient mix changes across hospitals or populations, the average treatment effect estimated by an RCT changes too. True, randomization guarantees internal balance, but the findings remain unhelpful for real-world critical care. By averaging opposing biological responses, trials can mask how treatment might save a bacterial patient while harming a viral one. Strong words. Takes guts.

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I’ve applied for Schengen Visas multiple times, and got all of them delivered within 6 working days! I’ve cracked a process that works for the salaried class. I have even built a detailed checklist + cover letter template. It helped my colleagues, and I want to help others. 🧵

How we use critical care ultrasonography in the management of cardiogenic shock: a strategic game of chess in intensive care CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evidenc…

8 minutes of Pure Bliss....😍😍😍😍 "_She is Just Outstanding 👌🏾👌🏻_"

Congratulations to Devika on securing first prize poster presentation in World ARDS meet Delhi!It's an achievement & acknowledgement of our collective effort of antivirals and immunomodulation therapy in Adenoviral ARDS @rakshay_shetty @bhat_chandrika @Manu_Delhi87 @DrPavitraV

Join us for an electrifying Cytokine Storm Symposium!Dive into cutting-edge insights with Dr. Randy Cron as he unravels "Personalized Approaches to Treating Secondary CSS." Don’t miss this chance to learn from a global expert! Register now! abhinavaglobalacademy.com/crs-registrati…

Cytokine Storm Symposium Alert! 🔬 Join Dr. Joe Carcillo as he unravels the phenotypes of cytokine storm in sepsis Hyper Inflammatory chaos to immune paralysis! management strategies must adapt!!A must-attend for all ! #CytokineStorm #Sepsis #CriticalCare abhinavaglobalacademy.com/crs-registrati…

Speaker Spotlight! Dr. Shanmuganathan Chandrakasan—immunology expert & Director of Immune Dysregulation at Emory—joins our #CytokineStorm symposium! He'll expose how PIDs can masquerade as cytokine storms 🔥🧬 Don’t miss this eye-opening session! abhinavaglobalacademy.com/crs-registrati…

Get ready for a surge of knowledge! Our #CytokineStorm Symposium features a powerhouse lineup of expert faculty you won’t want to miss. Don’t wait—register now for cutting-edge insights and dynamic discussions! abhinavaglobalacademy.com/crs-registrati…

Dr. A.V. Ramanan just delivered a powerful session on ‘Hyperferritinemia in Sepsis: When to Immunomodulate?’ at the Cytokine Storm Symposium — expert insights into timing, thresholds, and therapeutic windows. A masterclass in managing immune chaos!

Insightful talk by Dr.Brad Lindl in “ Infection specific cytokine storm “ Deep insights into an evolving field ! @PedsICU_tweets @IDSAInfo @UKSepsisTrust @SCCM @PediaLink @FrontPediatrics @PedCritCareMed @Manu_Delhi87

Thrombo-inflammation in sepsis: the crossroads of coagulation and immunity. The debate rages on—anticoagulate or immunomodulate?@bhat_chandrika and @VandanaBharad12 offer superb arguments on both sides ! @ASH_hematology @TheIMIDForum @vasudhanrao @EHA_Hematology

To immunomodulate or not? That was the question. Dr. Shanmughanathan C (For) vs. Dr. Pierre Tissières (Against) went head-to-head on ALF. Sparks flew. Minds opened. #ALF #Immunology #PedsICU @EmoryPedsICU @MayoClinicFLGIH @KingsCollegeLon @ILBS_India @NatRevGastroHep

Dr. Marco Gattorno delivers an insightful talk on “From Autoinflammation to Cytokine Storm: A Spectrum of Immune Dysregulation” at the Cytokine Storm Symposium — shedding light on the evolving landscape of hyperinflammatory responses @bhat_chandrika @mmdesai007 @TheIMIDForum

Mind-blowing session by Prof. Joe Carcillo on cytokine storm & sepsis phenotypes! A masterclass in immune dysregulation with cutting-edge therapeutic insights. If you missed it, you missed a lot @PedsICU_tweets @bhat_chandrika @OpenPicu @Pedicriticon24 @PedCritCareMed @SCCM

Dr. Andrew Boyle challenges conventional thinking on ARDS phenotypes. Is "inflammatory ARDS" a clinical reality or just a construct? A must-watch for anyone in critical care. #ARDS #PedsICU #CriticalCare #PIF @PedsICU_tweets @PediaLink @FrontPediatrics @PedCritCareMed

Dr. Ashish Kumar unravel the high-stakes link between early diagnosis & survival in cytokine storm! A must-watch for anyone dealing with pediatric malignancies. @AshishKumar_md @bhat_chandrika @vasudhanrao #PedsOnc #CytokineStorm #ChildhoodCancer #MedicalEducation

Dr. Shanmughanathan C delivered a powerful session on the often-missed overlap between primary immunodeficiencies and cytokine storm a true eye-opener . What you don’t see can hurt your patient! @EmoryPedsICU @FrontImmunol @APSID_PID @ESPR_ESN @TheIMIDForum

Dr. Jan-Inge Henter shared invaluable insights into the nuanced diagnosis and management of HLH in infants — blending science, experience, and clinical pearls from the pioneer himself. #HLH #PediatricHematology #CytokineStorm #PedsICU #MedEd @HistiocyteSoc