Cold Spring Harbor Laboratory

POV: You're at the Cold Spring Harbor Laboratory Symposium on Quantitative Biology: AI in Biology and your brain is trying to process all the paradigm shifts. The 90th year of #CSHLSYMP26 kicked off Tuesday May 26th with four opening talks by CSHL President Bruce Stillman, Jennifer Doudna @DoudnaJennifer @UCBerkeley, Alex Rives @biohub, Pushmeet Kohli @pushmeet @GoogleDeepMind and Hoifung Poon @hoifungpoon @MSFTResearch CSHL Symposia have helped spark some of the most transformative breakthroughs in modern science. The 1989 Symposium helped set the stage for the Human Genome Project. The 1978 Symposium on Recombinant DNA helped lay the groundwork for CRISPR gene editing. History has a way of starting here. This year, it's all about AI and its applications in biology research as well as clinical medicine.  In all, the Symposium will feature 9 oral sessions with 53 talks and over 200 posters in 3 sessions. Major themes include AI & Regulatory Genomics, AI & Evolution, AI & Cells & Tissues, AI and Clinical Translation & Precision Oncology, Neuro AI, Scientific Agents & Multimodal Models, and AI & Proteins. Scroll through for Day 1 highlights - part 1 What a way to open! #InspiringCuriosity #AIinBiology #CRISPR #PrecisionMedicine #MachineLearning #Biotechnology #InformationTheory #Claude #ScienceMakesLifeBetter

How AI models are providing insight into the tumor microenvironment and cancer therapy. My interview with Elham Azizi at the @CSHL Symposium on AI in Biology youtu.be/PzsUUbiliH0?si…

Brilliant talk by @TonyZador kicking off the #NeuroAI session at @CSHL 90th anniversary symposium

DAY 1- Part 2of2 POV: You're at the Cold Spring Harbor Laboratory Symposium on Quantitative Biology: AI in Biology and your brain is trying to process all the paradigm shifts. The 90th year of #CSHLSYMP26 kicked off Tuesday May 26th with four opening talks by CSHL President Bruce Stillman, Jennifer Doudna @DoudnaJennifer @UCBerkeley, Alex Rives @biohub, Pushmeet Kohli @pushmeet @GoogleDeepMind and Hoifung Poon @hoifungpoon @MSFTResearch CSHL Symposia have helped spark some of the most transformative breakthroughs in modern science. The 1989 Symposium helped set the stage for the Human Genome Project. The 1978 Symposium on Recombinant DNA helped lay the groundwork for CRISPR gene editing. History has a way of starting here. This year, it's all about AI and its applications in biology research as well as clinical medicine. In all, the Symposium will feature 9 oral sessions with 53 talks and over 200 posters in 3 sessions. Major themes include AI & Regulatory Genomics, AI & Evolution, AI & Cells & Tissues, AI and Clinical Translation & Precision Oncology, Neuro AI, Scientific Agents & Multimodal Models, and AI & Proteins. Scroll through for highlights of Day 1 What a way to open! #CSHLSYMP26 #InspiringCuriosity #AIinBiology #CRISPR #PrecisionMedicine #MachineLearning #Biotechnology #InformationTheory #Claude #ScienceMakesLifeBetter

#InspiringCuriosity with former Cynthia R. Stebbins Fellow and current CSHL Professor Adrian Krainer The legacy of the Fellows program began with Krainer in 1986. As the very first Fellow, Krainer is a shining example of the importance of supporting and investing in early career scientists. He explains that CSHL provided him with everything he needed and more to be where he is today. Where is he today? The Krainer lab uses a multidisciplinary approach to better understand the mechanisms of human RNA splicing. Krainer's research was utilized for the development of Spinraza, which became the first approved drug for spinal muscular atrophy (SMA). Spinraza has saved tens of thousands of lives to date and in March 2026, the FDA approved a higher-dose version Spinraza designed to further slow disease progression. Krainer has had an extraordinary impact on both the CSHL community and the broader scientific community. #InspiringInnovation #InspiringDiscovery #SMAAwareness #ScienceMakesLifeBetter

Cool new study from neuroAI specialist @klindt_david. Check out of some of his team's other research in the poster sessions at #cshlsymp26

CSHL Professor Dave Jackson is joining the likes of Isaac Newton, Benjamin Franklin, Charles Darwin, Albert Einstein, and Stephen Hawking as a Fellow of the Royal Society. The Royal Society recognizes, promotes, and supports excellence in science and encourages the use of science for the benefit of humanity.  Bruce Stillman, CSHL President & CEO, congratulates Jackson on this well-deserved election, as his research has progressed humanity's understanding of plant stem cell regeneration. #InspiringDiscovery #RoyalSociety #PlantBiology #ScienceMakesLifeBetter

Excited to join this amazing meeting next weeks @CSHL !

ICYMI: Molecular and therapeutic frontiers in anemia therapy: doi.org/10.1172/JCI203… In this Review, Nilesh Rai, Omar Abdel-Wahab @AbdelWahablab @MSKCancerCenter & Lingbo Zhang @Lingbo_Zhang @CSHL discuss current and novel interventions for #anemia. Figures: Signal transduction–based therapies for anemia (1/4); Genetic strategies for the treatment of anemia (2/4); Molecular mechanisms of spliceosome protein mutation–induced ineffective erythropoiesis (3/4); Targeting of neurotransmitter receptor CHRM4 to regulate early erythroid progenitor differentiation (4/4).

#Cancer cachexia is a wasting condition where patients lose significant amounts of skeletal muscle and fat. #PhF26 awardee Alice Wang @alicew0624 @stonybrooku @CSHL is studying the role of a hormone, apelin, in muscle wasting and regeneration. phrmafoundation.org/grants-fellows…

You’ve heard it takes a village to raise a child, but did you know that applies to some birds and fish, too? You might say it takes a whole band of scrub jays to raise a nestling. So, are our brains built for babysitting?  CSHL neuroscientist Katie Day is trying to answer that question. Have you heard of #DopamineLoops or #DopamineFarming on social media? It turns out mouse moms and surrogates know what that feels like, too! Watch Day break down the connection in our latest Cocktails & Chromosomes video. cshl.edu/videos/brains-… #InspiringCuriosity #neuroscience #ScienceMakesLifeBetter

Thank you @WomensHealthMag for covering this important new study, now the #1 trending story. Fish oil might not be as “brain-safe” as we’ve long assumed. A new study by CSHL Semir Beyaz and Onder Albayram of @MedUnivSC suggests that omega-3 supplements, specifically EPA, could actually interfere with brain repair after mild traumatic brain injuries like concussions. Important context: this is early research, not a clinical verdict—but it adds to growing questions about supplements vs. whole-food sources. Bottom line? Your brain may respond differently to nutrients during injury than in everyday health so you should check with your clinicians before taking supplements. What should you do with this information? Check out the Women's Health article. Link to Women's Health article: womenshealthmag.com/health/a712423…

2026 Summer Camp Enrollment at CSHL's DNA Learning Center is Now Open! Our immersive, five-day science summer camps are available at a DNA Learning Centers located in Long Island, Brooklyn, Westchester, and Wayne, NJ. Students entering grades 6–12 conduct hands-on experiments to explore the mysteries of life, learning real lab skills and building academic confidence—all while having fun and forging lasting friendships. Enroll today. Multi-camp, sibling, and employee discounts and scholarships are available. summercamps.dnalc.org #InspiringDiscovery #SummerCamp #ScienceMakesLifeBetter

Ever wonder how your brain knows to hold onto something? What even is learning? At the molecular level, one key player is a kind of brain receptor called an NMDAR. CSHL Professor Hiro Furukawa (@Lab_FURUKAWA) has dedicated his career to breaking down the structures of these important brain receptors. Now, Furukawa, postdoc Ruben Steigerwald, and colleagues have shown for the first time how NMDARs tell apart calcium and magnesium. Would you believe it involves dehydration?   The team's research offers new insight into the key molecular features of learning and memory. Additionally, it could have big implications for brain health and disease.  Special thanks to CureGRIN for helping to support this important work. Professor Furukawa is proud to be a part of the group’s Scientific Advisory Board.   Read more about this study at the link in bio cshl.edu/dehydrations-r… #InspiringCuriosity #RareDisease #GRIDisorders #BrainHealth #ScienceMakesLifeBetter @NatureNeuro

We're excited to share that Assistant Professor Helen Hou and her lab have been selected as one of the seven inaugural project partners of the International Brain Laboratory (IBL). cshl.edu/helen-hou-part… #InspiringDiscovery #ScienceMakesLifeBetter

Could singing mice hold clues to how human speech evolved? Thanks to @nytimes & Annie Roth for the great article spotlighting this new study & CSHL's Arkarup Banerjee and @TonyZador. nytimes.com/2026/05/06/sci…

CSHL’s Saket Navlakha (@navlakha_lab) and former grad student Cici Zheng (@CiCiZheng3) discovered a naturally occurring Voronoi diagram in Chinese money plant leaves. Their work could help explain how plants solve complex problems in nature and may one day help make sense of the math underlying life itself. Read more here: cshl.edu/natures-algori… #InspiringDiscovery #ScienceMakesLifeBetter @NSF, @NSERC_CRSNG, @NatureComms, @SimonsFdn

Congratulations to the CSHL Class of 2026! 🔬 Ranked #1 in NY, #6 nationally by @usnews. Meet these future science leaders! #InspiringCuriosity #Graduation #ScienceMakesLifeBetter cshl.edu/meet-the-schoo…