Dan Sutton

Everyone is talking about the ethanol fuel mandate being lifted. It is a zero sum game. E15 may be cheaper, but you get less miles per gallon, so you need to fill up your tank more often.

Effectively all growth in corn production over the last 20 years is for ethanol. ~20 million acres of conservation land, grassland, and soybean rotation was turned into corn monoculture that effectively strip mines the topsoil. Meanwhile it’s the most fertilizer dependent crop with only a 40% uptake rate. So ~1.7 million tons of nitrogen runoff flows into the Mississippi basin annually while also polluting their own water supplies. This runoff ends up expanding the Gulf deadzone, which is also where 40% of domestic seafood comes from. It’s hard to find a worse way to create fuel, with a wicked level of waste and downstream consequences.

My post about Bryan Johnson's 27mg 5-MeO-DMT livestream went viral last week. I pointed out that 27mg is massive relative to clinical research and that the broader facilitation landscape has a safety problem. I stand by that. But I've since learned something that added critical nuance to the picture. The Enfold Institute just published the protocol behind how that session was actually delivered. It's called the Leckie Protocol, and it's far more sophisticated than I realized. It's a dual-route method that combines intramuscular injection with vaporized inhalation in sequence. The IM dose goes first, followed immediately by the vaporized dose. Vaporization hits in seconds but metabolizes fast, while IM takes 3 to 5 minutes to onset and sustains for 30 to 45 minutes. By layering both, you get the full somatic release and ego dissolution from the vapor while the IM extends the session into a sustained therapeutic window that neither route can produce on its own. The dosing is also more precise than a single number suggests. The vaporized component typically ranges from 10 to 18mg freebase, and the IM component from 6 to 9mg freebase equivalent. These aren't guesses. They're calibrated individually based on a low-dose introductory session the day before, where facilitators observe each person's baseline sensitivity in real time. Body mass alone is not a reliable predictor with this molecule, meaning direct observation matters. This changes the picture for me: what looked like a reckless dose on a livestream was actually a carefully sequenced administration built on 650+ sessions of clinical observation. I could have done more homework before posting. My core point still holds. Most people sitting with 5-MeO facilitators don't have access to anything close to this level of rigor, and that gap is exactly the problem. But credit where it's due. The protocol itself is serious work. What standards should the field adopt to close that gap?

‘Dune is about religious fundamentalism and the danger of charismatic lead-“ Actually it’s about the importance supply chain diversification