Prostate Cell News

Prostate Cell News focuses on recent scientific journal articles covering prostate cell biology, cancer research, and related disease models. If you want to keep up with recent scientific discoveries in this field, then subscribe to receive free email newsletters delivered straight to your inbox. 📥 bit.ly/4kkWMEu

Drs. @AmyEngevik, Mindy (@micromindy), and Kirsten Engevik (@thekengevik) are avid about sharing their cell images and keen contestants of the #StemCellfie contest! 🎨 Learn about their tips and tricks for #immunofluorescence imaging in this @STEMCELLTech interview. bit.ly/47OsEMs

Drs. @scottdehm, Qi Cao, and Rendong Yang led this @NatureComms study investigating the interplay between super-enhancers and lncRNAs through analysis of lncRNA expression in a cohort of metastatic castration-resistant #ProstateCancer patients. 💡 go.nature.com/4lAqoPi

Drs. Bin Liang & Songnian Zou evaluate the therapeutic efficacy and immunomodulatory mechanism of exosome-delivered miR-1290 inhibitor in a #ProstateCancer mouse model. 👣 Follow the link here: go.nature.com/40zSGzY

Scientists with @UMMCMedicine's Drs. John Clark Henegan and Ajay Pratap Singh highlight the critical need for continued innovation in the development of personalized therapies to improve the clinical outcomes for patients with #prostate cancer. 🔗 go.nature.com/4sSwtcp

Researchers investigated physical and molecular interactions between poorly differentiated prostate cancer cells with exocrine or neuroendocrine features, which recapitulated pre-existing human CRPC-like cells, and decellularized prostate ECM. 🆕 bit.ly/4lvgeQ4

Scientists review frequently observed genomic aberrations affecting DNA repair pathways in #ProstateCancer. Patient selection needs improvement to identify the population that will most benefit from PARP inhibitor treatment beyond BRCA1/2 deficiency. 🧬 bit.ly/4uAni27

Chongqing Medical University's Drs. Yang Liao & Chuan Liu report in @SciReports that PRAC1 expression is upregulated in #prostate cancer cells and that PRAC1 knockdown represses the proliferation of prostate cancer cells. 🆕 go.nature.com/4uyATqH

Presented in @SciReports, Dr. Guangcheng Luo's team identified lnc-ALX1-2:10 as a novel lncRNA that promotes aggressive phenotypes in #ProstateCancer, highlighting its potential as a therapeutic target for #Metastatic disease. 🔎 Take a closer look: go.nature.com/4s9cPZQ

KDM5B is highly expressed in enzalutamide-resistant #CRPC. 💊 Scientists identified a mechanism linking metabolism, epigenetics, and a KDM5B/#androgen receptor feedback loop in drug resistance. 🤩 Check it out: bit.ly/4s7c2bR

Researchers from the Gwangju Institute of Science and Technology, including Dr. Steve Cho, establish the cereblon–6-phosphogluconate dehydrogenase axis as a critical metabolic checkpoint in #prostate cancer #metastasis. go.nature.com/4b5AToU

In early prostate cancer, FUS represses #AndrogenReceptor activity and tumor progression, leading to its down-regulation. Read the paper in @oncogenejournal! 📚 go.nature.com/4aII47y

Drs. Sumit Subudhi's team at @UTMDAnderson provides an overview in @jitcancer of the mechanisms of action of T cell engagers, including both CD3-targeted and CD28-targeted agents, and review the clinical development of these agents for #Prostate Cancer. bit.ly/4spOmit

Cardiff University's Drs. Daniel Turnham and Richard Clarkson report that inhibition of cFLIP in combination with either TRAIL or docetaxel has the potential to be used as a therapeutic approach to provide benefits to men with #prostate cancer. 🆕 go.nature.com/4reybUq

Scientists identified that the biogenesis of circPHGDH is regulated by ESRP1 in a lactylation-dependent manner. circPHGDH accelerated the malignant progression of #ProstateCancer via the miR-149/RAP1B axis. 🆕 go.nature.com/3ONqMOf

A new paper out of the Southern University of Science and Technology demonstrated the critical role of the epigenetic regulator UHRF1 in the enzalutamide resistance development of #ProstateCancer. 📃 Give it a read in @cddpress! 📚 go.nature.com/4rP8j2u

Paneth-cell-like prostate adenocarcinoma: nests of tumor cells with abundant eosinophilic granular cytoplasm, reminiscent of intestinal Paneth cells—an uncommon morphologic variant. Recognition is key to ensuring accurate grading. #Pathology #GUPath #ProstateCancer #MedEd

The Prostate Cancer Foundation (@PCFnews) announced $6.3 million in funding for 31 exceptional Young Investigators pursuing groundbreaking discoveries in #ProstateCancer. 🗞️: bit.ly/4slksfr

Dr. Yoshimasa Saito and colleagues investigate the genomic landscape of #mCRPC and evaluate the prognostic and therapeutic impact of pathogenic BRCA1/2 variants. 🧬 🆕 Don't miss this one: go.nature.com/3N7N9NP | @Nature_NPJ

🆕 New in @cddpress! Huazhong University researchers reveal a novel role for PDHA1 in mediating #ferroptosis resistance during ECM detachment and provide a potential therapeutic target for #ProstateCancer treatment. 🔗 go.nature.com/4rDVb00