Miguel Rodríguez de los Santos

149 posts

Miguel Rodríguez de los Santos

Miguel Rodríguez de los Santos

@RodrigMig

Biologist with a special interest in human genetics and neurodevelopmental disorders. Postdoctoral researcher in the Breen Lab @IcahnMountSinai @SeaverAutism

New York 가입일 Haziran 2018
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Miguel Rodríguez de los Santos 리트윗함
Adriano Bolondi, PhD
Adriano Bolondi, PhD@adrianobolondi·
🚨JOB ALERT🚨PLEASE SPREAD and RT Searching for a motivated Master’s student @LabBoke @CRGenomica @the_prbb to investigate how proteostasis in oocytes influences dormancy and fertility. Reach out to me (adriano.bolondi@crg.es) to join us in sunny Barcelona! See details below👇
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Adriano Bolondi, PhD
Adriano Bolondi, PhD@adrianobolondi·
As every time a door closes, new opportunities open up! From August I have joined @LabBoke in the beautiful @CRGenomica at @the_prbb to study oocyte cell biology during development and ageing! Reach out if you are in Barcelona and want to chat embryo stuff & more!
Adriano Bolondi, PhD tweet mediaAdriano Bolondi, PhD tweet media
Adriano Bolondi, PhD@adrianobolondi

Last week, I left @MPI_MolGen after 8 years of adventures. There are places in a person's life that leave an emotional mark, and this was one of them for me. Thanks to everyone who loved me; you were my second family and taught me the beauty and joy of research. See you all soon!

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Michael S. Breen
Michael S. Breen@breenPsychGene·
Our recent work with @SeaverAutism evaluating peripheral transcriptomic effects of #ketamine in children with #ADNP syndrome. @MountSinaiPsych @SinaiGenetics @SinaiBrain nature.com/articles/s4139…
Seaver Autism Center@SeaverAutism

New study from the #SeaverTeam! Ketamine significantly alters gene expression, especially in immune and inflammatory genes, shedding light on its therapeutic effects on the peripheral immune system. #autism #ADNP nature.com/articles/s4139…

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Miguel Rodríguez de los Santos
Miguel Rodríguez de los Santos@RodrigMig·
Microglia cells adapt to the circadian rhythm by going through transcriptional, proteomic and phenotypic alterations. Mattei et al. convincingly suggest: Mind the time, when you study #Microglia!!Wonderful work @DanieleMattei4 👏
Daniele Mattei, PhD@DanieleMattei4

Mind The Time! What time do you collect #microglia from your preclinical model for downstream analyses? Microglia undergo #transcriptional, #proteomic and #functional adaptations to the wake and sleep phases🧵sciencedirect.com/science/articl…

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Michael S. Breen
Michael S. Breen@breenPsychGene·
Our new article on A-to-I editing reveals differences in editing levels between postmortem and living brain tissues. Led by @RodrigMig & the Living Brain Project team: nature.com/articles/s4146… #RNAediting #ADAR #RNA @SinaiGenetics @IcahnMountSinai @MountSinaiPsych @SinaiBrain
Miguel Rodríguez de los Santos@RodrigMig

My first first-author publication as a postdoc “Divergent landscapes of A-to-I editing in postmortem and living human” is finally out in #NatureCommunications. 🤩 Scroll down for the most important insights. (1/11) doi.org/10.1038/s41467…

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Miguel Rodríguez de los Santos
Miguel Rodríguez de los Santos@RodrigMig·
And last but not least: This study is part of the Living Brain Project at @IcahnMountSinai and would have not been possible with all the collaborators involved. I want to thank you for all the support. A special thank you goes to my supervisor and mentor @breenPsychGene
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Miguel Rodríguez de los Santos
Miguel Rodríguez de los Santos@RodrigMig·
In conclusion, we were able to reveal differences in AtoI editing between living and postmortem brain driven by hypoxia and inflammation after organismal death. Our findings do not negate but instead, provide missing context for using postmortem brain tissues to study #RNAediting
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탐색

@LabBoke @CRGenomica @the_prbb @crisprscan @CABD_UPO_CSIC @DeRubeisLab @mgarcia_forn @BiologyOpen