Silvia De Rubeis

📣 New paper alert! In new work led by @MossaAdele out now in @NatureComms, we find that the autism risk gene #DDX3X is a critical regulator of sexual dimorphisms in neuronal neurodevelopment 🧬 🧠 nature.com/articles/s4146…

JOB ALERT!! We have an opening of a research assistant position in our lab @SinaiBrain for cognitive circuit and behavioral investigation using mouse models. 🐭 See the details below. Looking forward the applications!

#BrainAwarenessWeek is just heating up as @icahnmountsinai's Alexandra Ramirez, @AletaMurphy, Ashley Harlock & Corinne Smith drop their latest @SinaiNeuro Blogs (edited by the amazing Emma Hays)! Have questions? MiNDS has answers. DROPPING NEXT WEEK👉mindatsinai.com/blog

@tycheleturner So sorry for your loss, Tychele.

Rest in Peace, My Friend, Gabrielle ❤️! For those of you who contributed to Gabrielle’s Go Fund Me in the past when I posted it, I want to thank you. She was an amazing person and friend to me and my family. Prayers for her husband, Greg, and daughter, Catherine, and all the extended family. We will miss you, Gabrielle! smithfamilyfuneralhomes.com/obituaries/gab…

The Trump Administration is waging war on universities by suspending their funds. N.I.H. grants to universities are down by more than 90 per cent in the current fiscal year; so far in 2026, the National Cancer Institute hasn’t made a single grant. newyorkermag.visitlink.me/oxA7Ey

@InAnOther @DrJKhokhar Congrats Gisella!

How does the brain build a memory? A common assumption is that the neurons activated during an experience collectively form the memory engram. In our new Nature Neuroscience paper (finally out!), we show that this is not the case. nature.com/articles/s4159…

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers. The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇 For @Nature: nature.com/articles/d4158…

The cover of the Lancet. It says it all.

@_CarlaQ_ Nel caso le possano interessare questi fogli da colorare da vera scienziata in erba: cell.com/pb-assets/prod…

@DeRubeisLab 😊 ne sono certa!

"Che fai, Anna?" "Una presentazione multimediale sul fantastico mondo delle cellule". Certe volte, comunque, sbaglio pure io a chiedere.

@scrippsresearch @xinjin @SloanFoundation Congrats Xin!

Congrats to Scripps Research Assoc. Prof. Xin Jin (@xinjin), named a 2026 Sloan Research Fellow by the @SloanFoundation, recognized for pioneering in vivo Perturb-seq—a gene-editing approach combining CRISPR technology and single-cell RNA analysis to uncover how genetic variation shapes brain development. More at: ow.ly/Apez50YhaBw

🚨We're hiring a new editor!🚨 We're especially looking for someone with expertise in neurodegeneration and cellular/molecular neuroscience. Must have a Ph.D. and be able to work from Madrid, Shanghai, or Pune. Deadline to apply is March 9. springernature.wd3.myworkdayjobs.com/SpringerNature…

@BenschZimmer Congratulations!

Last week Julia, yesterday Jenice – two of my Aachen first‑generation PhD students smashed their thesis defenses. So proud of these awesome scientists and everything they’ve done, and super excited to see what they’ll get up to next. 🎓🚀

@BrielleRyan Congrats Bri!!

Our next chapter, starting June 2026 💗

On Feb. 23, the @FDA will host its virtual #RareDiseaseDay event. #RareDisease patients and advocates, don’t miss it! Learn how patient engagement, real-world data, and #AI tools ensure patient voices continue to shape #FDA decisions. RSVP: bit.ly/4abBNRD

I am SO incredibly excited to announce the launch of a global list of Inspiring Black Scientists. You can use this list to connect with researchers. Please share and join us in highlighting these outstanding scientists for #BlackHistoryMonth and beyond! wiley.com/en-us/research…

Dr. Dierdorff (@DeRubeisLab) brilliantly defended her thesis “Dissecting Cortical Circuits Driving Motor Deficits in a Mouse Model of DDX3X syndrome” in Dec. The Seaver Team is grateful for this alumna & her contributions to better understand rare disorders related to autism.

@SAOscience @NikosDaskalakis @McLeanHospital @harvardmed @broadinstitute Congrats Nikos & team!

🧠🧬 @McLeanHospital, @harvardmed, and @broadinstitute scientists are advancing human‑relevant psychiatric genomics by building tools that reflect ancestral diversity, something that fundamentally can't be captured using other species. Instead of relying on the same narrow datasets, @JajooAarti and collaborators used data from the PsychENCODE Consortium and @PsychiatricGen1 to improve genetically regulated expression models and how they're used in transcriptome-wide association studies. This approach allowed them to pull out signals that would’ve been missed otherwise, and revealed new genes that may be involved in the risk of developing bipolar disorder, major depressive disorder, posttraumatic stress disorder, and schizophrenia. As corresponding author @NikosDaskalakis put it, "Genetic diversity is a key to unlock the mysteries of the brain." ✨ Read the study in @NatureComms: nature.com/articles/s4146… 👥 also @athinara23, @artemis_iat, @thebigdeli, @mikejg84 🏢 also @sunydownstate, @dgsomucla, @LieberInstitute, @JHU_PBS at @HopkinsMedicine, @PennMedicine, @CHOP_Research This work was supported by @NIMHgov.

You can re-watch the Draft Pick here 👇🏼 m.youtube.com/watch?v=fW7_HD…

What a night for #RareDisease research & community! 🦓 🏈 Congrats all draft picks and especially our very own @Jer0nimoLukin 💪 A million thank you @ddx3x, @UpliftingAth, @RobLong47, @BrettBrackett! Together #WeTackleRare!

@Taylor_Michael3 @UpliftingAth @MLB @MLBPA @Royals @KCRoyalsFdn Thanks for your advocacy for rare diseases 🦓! #WeTackleRare

Excited to be back on the field supporting the #RareDiseaseCommunity with @UpliftingAth! You can join us be pledging for each hit I have through the remainder of the @MLB season in my Hits For Rare Disease campaign! pledgeit.org/michael-taylor… .