
Biology Open
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Biology Open
@BiologyOpen
Facilitating rapid review for accessible research - an online only, #OpenAccess peer reviewed journal for research across all aspects of the biological sciences









The AXL-Golgi story... has two parts, both of which are now published. 1) AXL receptor tyrosine kinase regulates Golgi organization and function via an adhesion-Arf1 signaling axis in breast and lung cancer cell lines tinyurl.com/AXLGolgi1 @BiologyOpen 2) Differential AXL expression and Arf1 regulation control stiffness-dependent Golgi organization in breast cancer cells tinyurl.com/AXLGolgi2 @J_Cell_Sci Together, they make for a comprehensive story identifying the role of AXL in controlling Golgi organization and its regulation by mechanosensory cues (matrix stiffness). Work started as a simple screen by Prachi to pick AXL as a gene of interest, taken forward by @ArnavSaha19 and @Tush96rkhane. Supported ably by many others. It's also nice to be able to use data from Vibhas's @SVibha1 studies in this paper, as she identified the adhesion-Golgi connection many years ago. Congratulations to all involved in this study, which was challenging and exciting in equal measure.




























