Silberstein Lab

This @NatureGenet study screened for somatic mutations in healthy aged individuals, identifying expanded HSC clones accessible for lineage tracing of all major blood cell lineages. 🩸 ✅ Check it out! go.nature.com/3LC2rcH

Thrilled to share our work on the role of taurine in myeloid leukemia progression in @nature today! nature.com/articles/s4158…

Thank you to the wonderfully talented Rioka Hayama riokahayama.com for blending the senior author’s two passions - classical music and biology - to capture the essence of our paper nature.com/nataging, and to Nature Aging editors for choosing it as the cover art.

@LabAgarwal Thank you very much, Anupriya!

@Silberstein_Lab Congratulations beautiful story

How do hematopoietic stem cells resist inflammatory damage and do not age prematurely? Turns out that Semaphorin 4A-producing neutrophils come to rescue, as we report in our first paper, out in Nature Aging rdcu.be/d7UvQ. Cudos to 36 coauthors, reviewers and NA editors!

@TakizawaLab Sounds like a very good reason to come, will try!

@Silberstein_Lab Why don't we discuss at ISEH meeting in Kumamoto this year?

@SanjayPatelMD Thank you, Sanjay!

@Silberstein_Lab Huge congrats, Lev!

@PapapetrouMDPhD Thank you, Eirini - took a few years....

@Silberstein_Lab Congrats @Silberstein_Lab ! Happy to see this work out!

@TakizawaLab Thank you - hope we can discuss these data in person soon!

@Silberstein_Lab Congratulations on your great work!

@DrMonicaGuzman Thanks so much, Monica! Look forward to brainstorming more about this!

@Silberstein_Lab Congrats! Very interesting work!

@RohanKhadilkarr Thank you - very glad to hear!

@Silberstein_Lab Very interesting article! Congratulations to all the authors 🎉🎊

@LabWaggoner @NatureAging thank you for spreading the word about our work!

Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells @NatureAging nature.com/articles/s4358…

Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s4158…… @MartinJLercher

We are looking for a technician and a post-doc. If you know anyone who's interested in pre-leukemia/inflammation/the niche and enjoy exploring nature, please ask to RT or email lsilbers@fredhutch.org. Thank you!

Truly wonderful to reconnect with old colleagues and meet new ones at Mol Haematopoiesis meeting in London. Thank you for the opportunity to hear tremendous speakers and present our data, and to Doug Higgs for his inspirational advice "to enjoy every day of doing science".

We are looking for a new Technician colleague to study the biology of HSC and their niches in inflammation, pre-leukemia and aging. Will fully support anyone who is interested in becoming a leader for their project. DM/email lsilbers@fredhutch.org to explore this opportunity.

We currently have two post-doctoral positions for those interested in studying how niche factors can be converted into drugs to prevent leukemic evolution and inflammation-induced HSC damage. Please DM or email lsilbers@fredhutch.org to find out more!

@CterminiPhD Thank you, Tina!

@Silberstein_Lab @EdwardPEvansFdn @edie_crosse @StanleyCLee @JShendure @SteidlUli Amazing news. Congrats, Silberstein Lab!

Grateful and honored to have our MDS work now supported by @EdwardPEvansFdn Discovery grant! Thank you to @edie_crosse and others in the @Silberstein_lab for input and preliminary data. Look forward to working with @StanleyCLee, @JShendure and @SteidlUli on this exciting project!

@Gritsman_lab Thank you, Kira!

@Silberstein_Lab @EdwardPEvansFdn @edie_crosse @StanleyCLee @JShendure @SteidlUli Congrats Lev!