mephoria

Dad's workouts may shape his child's endurance capacity and metabolic health. Not by passing on mitochondria—which come from mom—but by sending tiny sperm microRNA messages that tune early embryonic gene regulation. In a new study (mice), exercising fathers produced offspring with a higher VO2 max, greater endurance, a leaner body composition, and more mitochondria. They also had superior glucose control and insulin sensitivity when challenged with a high-fat diet. Effects tracked to sperm small RNAs that suppressed a "molecular brake" on PGC-1α, the classic mitochondrial biogenesis switch. This reframes preconception health as a two-parent story: mom supplies the mitochondria, but dad’s training status can still program how those mitochondria are used.

Damn! #MyXAnniversary

Do you remember when you joined X? I do! #MyXAnniversary

I created a course that ~26,500 people took. It took me 3-months to make. That same course TODAY would take less than 1 week to make. Thanks to AI. I created a guide to show you to avoid months of pain. Want it free? - *Must follow* - Reply ‘speed’ I’ll DM you a copy.

@iamkylebalmer Speed

@Darosham_ Hook

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@ianmiles I don't know, are you suggesting that he share it with everyone on there? It's hard to be fair to that many people. Drugs are expensive

How is this fair to anyone else sitting in that carriage? twitter.com/ClownWorld_/st…

@auroraonx AI thanks, always like your content!

@auroraonx AI

US Senator Warren lied about crypto being used by Hamas and North Korea. Now she's sponsoring a bill that will effectively ban crypto in the United States. Never forget that these people hate you. We will fight back. We will win.

@gdb This company is over, strategic takedown. I've seen it many times. No matter what the reasoning for it, the outcome will be that they fall behind and it will be over.

Sam and I are shocked and saddened by what the board did today. Let us first say thank you to all the incredible people who we have worked with at OpenAI, our customers, our investors, and all of those who have been reaching out. We too are still trying to figure out exactly what happened. Here is what we know: - Last night, Sam got a text from Ilya asking to talk at noon Friday. Sam joined a Google Meet and the whole board, except Greg, was there. Ilya told Sam he was being fired and that the news was going out very soon. - At 12:19pm, Greg got a text from Ilya asking for a quick call. At 12:23pm, Ilya sent a Google Meet link. Greg was told that he was being removed from the board (but was vital to the company and would retain his role) and that Sam had been fired. Around the same time, OpenAI published a blog post. - As far as we know, the management team was made aware of this shortly after, other than Mira who found out the night prior. The outpouring of support has been really nice; thank you, but please don’t spend any time being concerned. We will be fine. Greater things coming soon.

@elonmusk Is anyone surprised that there's not a community note on this...

The way to beat hatred is friendship

@dom_lucre @Tiffany_Gomas @Delta @united @SouthwestAir Well, she is a marketing executive, so there's that.

@Tiffany_Gomas @Delta @united @SouthwestAir How does everything you do look so official already?

Give us your best rendition of the infamous plane fit 🎃👻Winner will receive two domestic first class tickets or priority passes on @delta @united or @southwestair 🎟️✈️ tag your friends to increases the chances of winning a flight for two! To enter: post your costume and use the hashtag #TMFINR by 10/31. Winner will be announced on 11/4 🏆 #happyhalloween #costumecontest #halloween #giveaway #freeflight #notrealplanewoman #TMFINR #travel #southwestairlines #unitedairlines #deltaairlines #nypost #travelhack #costumeideas

@BingIsAGoodBot @Jakeyoung841084 🤣

Oliver Sacks' experience with a massive dose of the tropane-related anti-Parkinson's drug Artane (trihexyphenidyl) is a perfect example of a "true hallucination" elicited by deliriant psychedelics -- hallucinations that, unlike those of the classic psychedelics, don't announce themselves as such: "So one Sunday morning, I counted out twenty pills, washed them down with a mouthful of water, and sat down to await the effect. Would the world be transformed, newborn, as Huxley had described it in The Doors of Perception, and as I myself had experienced with mescaline and LSD? Would there be waves of delicious, voluptuous feeling? Would there be anxiety, disorganization, paranoia? I was prepared for all of these, but none of them occurred. I had a dry mouth, large pupils, and found it difficult to read, but that was all. There were no psychic effects whatever—most disappointing. I did not know exactly what I had expected, but I had expected something. I was in the kitchen, putting on a kettle for tea, when I heard a knocking at my front door. It was my friends Jim and Kathy; they would often drop round on a Sunday morning. “Come in, door’s open,” I called out, and as they settled themselves in the living room, I asked, “How do you like your eggs?” Jim liked them sunny side up, he said. Kathy preferred them over easy. We chatted away while I sizzled their ham and eggs—there were low swinging doors between the kitchen and the living room, so we could hear each other easily. Then, five minutes later, I shouted, “Everything’s ready,” put their ham and eggs on a tray, walked into the living room—and found it completely empty. No Jim, no Kathy, no sign that they had ever been there. I was so staggered I almost dropped the tray."

@rawsalerts So they sounded the sirens this time, weren't they afraid that people would run into the fire after they hear the sirens?

🚨#BREAKING: Emergency sirens are sounding off as a Level 3 Evacuation Order has been Issued for a Approaching Brush Fire

📌#Kaanapali | #Hawaii Emergency Sirens are sounding as the Maui Emergency Management Agency has issued a Level 3 evacuation order for kaanapali in West Maui, Hawai due to a Approaching Brush Fire multiple firefighters are on the scene battling the fire officials are advising everyone to evacuate and stay clear of the area until it is safe to return officials say residents will be informed when they can return home, and the traffic is also being stopped. The brush fire is happening less than five miles north of Lahaina.

@mbateman Great advice, and all of your example vids are spot on. I was hoping you'd clarify the focal subject for those parents that leave kids be while on electronic devices.

One of the few pieces of parenting advice that I’m highly confident in and think generalizes widely across personalities, family cultures, ages: If your child is concentrating on doing something, don’t interrupt. Don’t correct, don’t compliment, don’t join in. Leave them be.

@IanCrossland Nice job, but are you holding the camera with your foot...not subbing if you stick with the drunk camera person.

Workout: Week 4 Short burst of bicep curls. The pain is starting to pinch less. Weights are increasing. Subscribe for more workout vids.

10 good reasons, why #Bitcoin is going to be parabolic in this cycle. A 🧵 by Stockmoney Lizards🦎

8,000,000,000 people and 21,000,000 Bitcoin. Of these, approximately 4,000,000 are very likely no longer accessible. 1,000,000 are owned by Satoshi. 1,500,000 Bitcoin are still destined to be mined for the next 117 years. 14,500,000 divided by 8,000,000,000. If we delete six decimal places from the dividend and divisor in this equation, we get 14.5 Bitcoin for every 8,000 people. Imagine 8000 people scrambling to drink the last 14.5 liters of liquid. 8000 people fighting for the last 14.5 units of a perfect security that exists. A bottom level based, physical/mathematical Noah's Ark available for everyone. Guys, when the last piece of fiat money is dying, 1 Bitcoin is worth so much immeasurably. No one will be able to comprehend the magnitude. 1 Bitcoin will carry an amount of value that few understand how much value even ⅒ of a Bitcoin has. Even in 20 years, when in 2044 the block subsidy will be for the first time below 10% of a Bitcoin, we will probably never understand how much value this tenth part of 100,000,000 Satoshi will be for our society and our distant descendants. The mathematics and brilliance behind Bitcoin should leave us in awe with gratitude and as time progresses more and more people are realizing this. We are so damn early, take the chance.