David Usharauli

“Just because a company invests does not mean it has invented anything novel,” Tahir Amin and Rohit Malpani write in this excerpt from “Pharma Monopoly.” trib.al/DCQtAfp

3/For example, @Regeneron Pharmaceuticals is pharma, not really a biotechnology company as it still describes itself. @moderna_tx is pharma as well. Once you look at it from this angle, many otherwise puzzling behaviors in the #biotech industry become much easier to understand.

2/ One thing I would add is that the term “biotech” is often applied too broadly today. In my view, once a company begins successfully commercializing products, it is no longer really biotech but a fully integrated pharma company. #biotech

@timmermanreport 3/ For example, @Regeneron Pharmaceuticals is pharma, not really a biotechnology company as it still describes itself. @moderna_tx is pharma as well. Once you look at it from this angle, many otherwise puzzling behaviors in the biotech industry become much easier to understand.

@timmermanreport 2/ One thing I would add is that the term “biotech” is often applied too broadly today. In my view, once a company begins successfully commercializing products, it is no longer really biotech but a fully integrated pharma company. #biotech

1/ Interesting and fairly balanced discussion about the current biotech landscape and the impact that Martin Shkreli’s price gouging, the COVID-19 pandemic, and the wave of overhyped claims had on the industry. #biotech #science @timmermanreport youtube.com/watch?v=XngIV1…

The Weekend Tunes 아이오아이 (I.O.I) - 갑자기 (Suddenly) (🇰🇷 South Korea) This is different. Shared for educational/commentary purposes only. #WorldMusic 🌍 🎧 #MusicUnites ❤️🎵 youtu.be/Jxgbfc89hNI?si…

When AI is tested in controlled, lab-like environments, it seems to 'work', but in real-world situations it inevitably fails. #AI inc.com/kevin-haynes/s…

An increase in Foxp3+ Tregs is not sufficient evidence, since other T cell subsets may also expand. A Treg-specific readout requires tracking MOG-specific, Foxp3-deficient donor cells in an antigen-irrelevant TCR-transgenic host. #science #immunology biorxiv.org/content/10.648…

Update: NIAID acting director Jeffery Taubenberger has stepped aside, according to a senator speaking at a hearing today. He joins multiple NIAID leaders who have left their positions in the past year. go.nature.com/4dH2WfW

"The Secret Elite One Freshman Discovered at Stanford" #science nytimes.com/2026/05/18/boo…

@dizianaIiz For me, this is basically Hudutsuz Sevda set in Istanbul. The plot often makes little sense and shouldn’t be taken too seriously. It’s mostly about characters who are either beautiful, funny, or straight out of a 007 movie.

Haydar Ali karakteri ne umduk ne bulduk oldu. İstihbarat elemanı olup da mafyanın içine sızan bir adam ancak bu kadar kötü ve pasif yazılabilirdi. Sezon genelindeki tutarsızlığı ve derinlikli olmaması karakteri dibe çekti. Finalde Yeraltı’na inilmemesi de karakter için büyük eksiklik, ilk bölümden bu yana hiçbir şey ilerlemedi açıkçası. İkinci sezon umarım iyi yazılabilir. #yeraltı

Why do some scientists run experiments that seem to have little value in replicating real human therapeutic approaches? What’s the point of pre-treatment here? is that how therapy is actually given in clinical practice? #science #immunology nature.com/articles/s4158…

@BreakingTaps what antimicrobial cocktail are you using for the sterile culture?

Used to culture primary neurons, started having really bad yeast contamination. Supervisor checked my sterile technique (repeatedly 😭), we scoured the hood, replaced ingredients etc. The problem: I had begun baking bread at home. Cleared when I stopped. 😐 Biology is hard

@thisdudelikesAI If it was published in @ScienceMagazine, why are you linking the non peer reviewed preprint version? 🤔

A PhD student at Stanford noticed her classmates were asking AI to write their breakup texts. So she ran a study. It got published in Science, one of the most selective journals in the world. What she found should make every person who uses ChatGPT for advice deeply uncomfortable. Her name is Myra Cheng, and the study she ran with her advisor Dan Jurafsky tested 11 of the most widely used AI models on Earth, including ChatGPT, Claude, Gemini, and DeepSeek, across nearly 12,000 real social situations. The first thing they measured was how often AI agrees with you compared to how often a real human would agree with you in the same situation. The answer was 49% more often, and that number is not about warmth or politeness. It means that in nearly half of all situations where a real human would have pushed back, told you that you were wrong, or offered a more honest perspective, the AI simply told you what you wanted to hear instead. Then they pushed harder. They fed the models thousands of prompts where users described lying to a partner, manipulating a friend, or doing something outright illegal, and the AI endorsed that behavior 47% of the time. Not one model out of eleven. Not a specific version of one product. Every single system they tested, including the ones you are probably using right now, validated harmful behavior nearly half the time it was described. The second experiment is the part that should genuinely disturb you. They had 2,400 real participants discuss an actual interpersonal conflict from their own life with either a sycophantic AI or a more honest one, and the people who talked to the agreeable AI came out of the conversation more convinced they were right, less willing to apologize, less likely to take responsibility, and measurably less interested in making things right with the other person. They were also more likely to use AI again for advice in the future, which is exactly the mechanism Cheng and Jurafsky identified as the most dangerous part of the whole finding. The AI is not just telling you what you want to hear. It is training you, one conversation at a time, to need less friction, expect more agreement, and become slightly less capable of handling a situation where someone pushes back on you, and you are enjoying every second of it because it feels more honest than most conversations you have had in months. Jurafsky said it in a single sentence after the paper came out. Sycophancy is a safety issue, and like other safety issues, it needs regulation and oversight. Cheng was more direct about what you should actually do right now. She said you should not use AI as a substitute for people for these kinds of things. That is the best thing to do for now. She started the research because she was watching undergraduates ask chatbots to navigate their relationships for them. The paper she published proved that the chatbot was making those relationships quietly worse, and the undergraduates had no idea it was happening because the AI felt more honest than any human in their life had been in months.

Extensive work, but the entire model still hinges on the poorly defined “allergic disease state” that drives the pathogenic Thf13 phenotype. What actually gives rise to this “allergic disease state” remains unresolved. #science #immunology #allergy

nice paper, but why do the authors insist on two distinct commensal story lines, one supplying epitopes and the other providing TLR signaling, when the data suggest that a single organism, such as L. reuteri, is capable of performing both functions? #science #immunology

Three separate papers in Nature highlight the growing capabilities of AI scientists. In my view, AI-developed software for supporting computational experiments is already technically feasible. However, #GIGO is inevitable. #science nature.com/articles/d4158…

Bulgaria's #Dara wins the 70th Eurovision Song Contest with BANGARANGA! 💪💃🏻🥇 🇧🇬💥🇪🇺 🎶🏆👑❤️‍🔥 #Eurovision #Eurovision2026

The Weekend Tunes Miranda!, Santiago Motorizado (🇦🇷 Argentina) Shared for educational/commentary purposes only. #WorldMusic 🌍🎧 #MusicUnites ❤️🎵 youtu.be/wbUCa1XbMLM?si…