
Tracking how blood moves through the brain is critical for studying neurological disease, yet accurately measuring that flow in small-scale preclinical models has seen limited progress.
To establish more reliable measures of cerebral circulation, researchers tested the accuracy of phase-contrast MRI and established reference values for major intracerebral arteries and veins in a preclinical model.
The study combined controlled flow phantom testing with in vivo measurements, using semi-automatic image segmentation to quantify blood movement and pulsatility across key vessels. Results showed strong agreement between MRI-derived measurements and reference pump values, while also confirming balanced cerebral inflow and outflow and symmetrical circulation between the left and right sides of the brain.
By strengthening the accuracy of preclinical brain-flow measurements, this work could help accelerate earlier detection and better treatment of neurological disease.
𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: link.springer.com/article/10.100…
𝗦𝘁𝘂𝗱𝘆: Characterization of Arterial and Sinus Blood Flow Dynamics Using Phase-Contrast MRI
𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Sidy Fall, Kamel Abderrahim, and Olivier Baledent
@UPJV_Univ
𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: link.springer.com/journal/10439

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