Dave Hughes

22.3K posts

Dave Hughes

@HughesDC_Muscle

Assistant Professor | @AM_OMRF | Skeletal Muscle, Atrophy, Aging, Protein Quality Control (PQC) | Views my own | 📚💪🏼🇬🇧 #myotwitter

Oklahoma City, OK Katılım Ağustos 2011

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Dave Hughes@HughesDC_Muscle·20 Kas

Final Version of our article on UBR-box E3 ubiquitin ligases, protein synthesis and skeletal muscle size now online 🚨 | @AJPCellPhys @CraigAGoodman1 @DrAdamPSharples | journals.physiology.org/doi/full/10.11… Review in this area recently published here: journals.lww.com/acsm-essr/full… #Myotwitter

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Centre for Muscle Research@UniMelbCMR·2d

Congratulations to the CMR's Dr Alastair Saunders @AlastairSaund from the @pgregorevic Lab for his new review, "Understanding cachexia and muscle dysfunction in the context of metastatic breast cancer" @CancerCachexia #myotwitter link.springer.com/article/10.100…

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Craig A. Goodman@CraigAGoodman1·3d

Congrats to Dr Chris Karagiannis @CKaragiann11012 of the @pgregorevic Lab for his first first-authored paper "Sex-divergent skeletal muscle remodeling emerges early in cancer cachexia" in @AJPCellPhys #myotwitter journals.physiology.org/doi/abs/10.115…

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Dave Arnold@DaveArnoldLab·10 Tem

It is finally out! JCI - Neuromuscular junction failure in sarcopenia is linked to NaV1.4 loss and reversed by ClC-1 inhibition jci.org/articles/view/…

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Craig A. Goodman@CraigAGoodman1·10 Tem

Emerging Mechanisms Associated with Disuse-Induced Skeletal Muscle Atrophy sciencedirect.com/science/articl…

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Gilles Gouspillou@GGouspillou·4 Tem

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle | Nature Aging nature.com/articles/s4358…

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Christopher Fry@ChrisFryPhD·29 Haz

Here we profile senescent cells across musculoskeletal tissues at a single cell level in a preclinical ACL injury model, identifying shared and divergent senescent profiles within muscle and the knee joint itself

Alex Keeble@AlexKeeble5

Excited to share a new publication from the @ChrisFryPhD and @Allison_M_Owen labs! We identify senescent macrophages as contributors to quadriceps atrophy and PTOA following ligament injury. Proud to have contributed to this work with an amazing team. pubmed.ncbi.nlm.nih.gov/42348390/

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American Physiological Society@APSPhysiology·25 Haz

Her #Physiology career has taken her from Moscow to biotechs and many stops in between. Now, Sue Bodine is poised to lead the APS as its incoming president. Learn more about her amazing journey in this May #TPhysMag profile: ow.ly/BbT150ZcTVB #WeArePhysiology

American Physiological Society tweet media

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Centre for Muscle Research@UniMelbCMR·24 Haz

Congratulations to the CMR's @yaankitn, @BenParkerLab and Team for their new paper "Quantitative interactome mapping of skeletal muscle insulin resistance" . #myotwitter link.springer.com/article/10.103…

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Craig A. Goodman@CraigAGoodman1·22 Haz

Age-related anabolic resistance and post-absorptive muscle protein synthesis: integrative evidence from a systematic review and meta-analysis frontiersin.org/journals/physi…

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Adam Sharples Ph.D -Blue Sky🦋@profadamsharples@DrAdamPSharples·17 Haz

New preprint! doi.org/10.64898/2026.… In BMI-discordant twins we integrate multi-omics across adipose & muscle Exercise reprograms adipose, shifting heavier twins towards a leaner baseline. Muscle improves insulin sensitivity & key molecular adaptations @JHentil @MaxUllrich94

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OMRF@OMRF·3 Haz

👏 Way to go!!!

Dr. Chi Fung Lee@ChiFungLeePhD

Great work from @w_zarzycka for the young Investigator award and @HinaLateef for travel award and great talks @ISHR_NAS. we are proud mentors @ChiFungLeePhD @AnnChiaoPhD @OMRF @OUHSC_GPiBS

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Harrison Finn, PhD@HarrisonFinn·28 May

In Memoriam: V. Reggie Edgerton - Lieber - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/full/10.11…

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Craig A. Goodman@CraigAGoodman1·28 May

Multicellular senescence impairs skeletal muscle recovery following disuse in aging science.org/doi/10.1126/sc…

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OMRF@OMRF·21 May

We welcomed two new Board Directors and awarded multiple scientists for their research at yesterday's spring Board meeting. Read more: omrf.org/omrf-board-wel…

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Dave Hughes@HughesDC_Muscle·13 May

MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo | #myotwitter pubmed.ncbi.nlm.nih.gov/42120991/

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Simone Porcelli@PorcelliSimone·10 May

Finally out the data we collected in the over90 200m world record holder. Read if you are interested in knowing how aging can be modified by lifelong training #longevity #physiology journals.physiology.org/doi/abs/10.115… journals.physiology.org/doi/abs/10.115…

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Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM@agingdoc1·8 May

The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine cell.com/trends/biochem…

Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM tweet media

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Dave Hughes@HughesDC_Muscle·9 May

Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway #myotwitter pubmed.ncbi.nlm.nih.gov/42102209/

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AJP-Cell Physiology@AJPCellPhys·7 May

Brand new #ArticleinPress today! Overactive PDGFRα and PDGFRβ promote distinct phenotypes of skeletal muscle #fibrosis and stiffness, with PDGFRβ also driving #muscle growth (Mariola Gimla et al. @OMRF): ow.ly/Z3xq50YVv10

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Gilles Gouspillou@GGouspillou·1 May

The final version of our latest paper is now online: BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics. sciencedirect.com/science/articl…

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Keşfet

@AlastairSaund @pgregorevic @CancerCachexia @CKaragiann11012 @AJPCellPhys @yaankitn @BenParkerLab @JHentil