Acarin Inc

I’ve always believed the No.1 application of AI should be to improve human health. That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine drug discovery and one day solve all disease! We are turbocharging that goal with $2.1B in new funding.

@PrismML It’s exciting to imagine stepping from the mainframe age into the iPhone era of intelligence! Kudos to the @PrismML team!

Today, we are emerging from stealth and launching PrismML, an AI lab with Caltech origins that is centered on building the most concentrated form of intelligence. At PrismML, we believe that the next major leaps in AI will be driven by order-of-magnitude improvements in intelligence density, not just sheer parameter count. Our first proof point is the 1-bit Bonsai 8B, a 1-bit weight model that fits into 1.15 GBs of memory and delivers over 10x the intelligence density of its full-precision counterparts. It is 14x smaller, 8x faster, and 5x more energy efficient on edge hardware while remaining competitive with other models in its parameter-class. We are open-sourcing the model under Apache 2.0 license, along with Bonsai 4B and 1.7B models. When advanced models become small, fast, and efficient enough to run locally, the design space for AI changes immediately. We believe in a future of on-device agents, real-time robotics, offline intelligence and entirely new products that were previously impossible. We are excited to share our vision with you and keep working in the future to push the frontier of intelligence to the edge.

Will start one at Columbia, MD soon.

This 40 minute lecture from Peter Thiel at Stanford will teach you more about business competition than a 2 year MBA program

🚨 CANCEL YOUR SaaS SUBSCRIPTIONS We will soon be launching agentic templates where you can install your favorite SaaS products in one click! An AI agent will spin up and vibe code a complex software system Initial launch targets - CRM for sales and leads - contract management - campaign management - bug tracker - internal wiki The best part - you can customize these apps any which way ❤️

Unsloth now has 1.8x-3.3x faster 20% less VRAM embedding finetuning! EmbeddingGemma, Qwen3 Embedding & all others work! We made 6 notebooks showing how you can customize for RAG, semantic similarity tasks & more. Transformers v5 works as well. Thanks @huggingface for the collab!

AGI House hosted a focused technical workshop at the frontier of AI × healthcare. 8 hours. Real constraints. Agentic systems aimed at enterprise-grade impact across drug discovery, biomedical data, and healthcare ops. Thank you @mithrl_ai!

@bindureddy 👋

Each passing day, I am becoming terrified that there are really very few humans on X I need my monthly reassurance that biological intelligence is still present Say hello or wave 👋, if you are human?

This would make everyone to afford to own a self-driving cars that drives safely.

Gemini 3 Flash is insane at OCR. It parses this extremely hard to read handwritten letter by Richard Feynman perfectly. It can do ~300 of these for $1. What's crazy is Feynman addresses General Donald J. Kutyna as "Katyna" which Gemini gets. There is no "Meeting Katyna", the first part of the letter, in all of Google search!

Android Emergency Live Video launched. You can now easily share vital visual information with one tap to emergency services so they can assess situations faster and guide you through life-saving steps until help arrives. blog.google/products/andro…

It is a very smart model, and we have come a long way since GPT-5.1:

Less is More. We’ve simplified the sidebar experience on Perplexity web. Great work by Pete.

We are not slowing down in December. - OpenAI to release a GPT-5.2 to challenge Gemini 3 - SOTA video model from Kling - Amazon's new Nova model just dropped! - DeepSeek will launch an agentic version of V3.2 The Party Never Stops....

“There’s a lot of context in the data enterprises have. It’s proprietary and not available to LLMs. Providing that data as context to agents is going to be the big unlock.” Databricks co-founder and CEO @alighodsi explains how combining enterprise data with OpenAI’s models can reshape what AI agents can do in the enterprise. Watch the full conversation with @OpenAI co-founder and CEO @sama. youtube.com/watch?v=gz1sOE…

@pratyusha_PS Congratulations!

📢 Some big (& slightly belated) life updates! 1. I defended my PhD at MIT this summer! 🎓 2. I'm joining NYU as an Assistant Professor starting Fall 2026, with a joint appointment in Courant CS and the Center for Data Science. 🎉 🔬 My lab will focus on empirically studying the science of deep learning and applying deep learning to accelerate the natural sciences. Very broadly interested in questions at the intersection of language, reasoning and sequential decision making. (Plus any other fun problems that catch our eye along the way!) 🚀 I am recruiting 2 PhD students for this cycle! If you're interested in joining, please apply here: cs.nyu.edu/dynamic/phd/ad… cds.nyu.edu/phd-admissions…

@calcsam Thanks for sharing and looking forward to read. Please DM me the copy. thanks.

icymi we wrote a new agents book: patterns for building ai agents it has everything you need to take your agents from prototype to production, like agent design patterns, the basics of security, etc reply to this tweet with BOOK and we'll dm you so you can get a copy

You asked for it. We built it. A library of architectural diagrams that show practical ways to build pipelines, dashboards, and AI models. Find designs for common data and AI builds across use cases and industries, including: - Data Ingestion - AI Security Framework - Next Best Action - and more! databricks.com/resources/arch…